Reactome | GIPC1 [cytoplasm]

GIPC1 [cytoplasm]

Stable Identifier

R-HSA-9839329

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasm

Synonyms

PDZ domain-containing protein GIPC1, GIPC1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P06463 VE6

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External Reference Information

External Reference

UniProt:O14908 GIPC1

Gene Names

GIPC1, C19orf3, GIPC, RGS19IP1

Chain

chain:1-333

Reference Genes

BioGPS Gene:10755 GIPC1

COSMIC - genes:GIPC1 GIPC1

CTD Gene:10755 GIPC1

dbSNP Gene:10755 GIPC1

ENSEMBL:ENSG00000123159 GIPC1

HGNC:1226 GIPC1

KEGG:hsa:10755 GIPC1

Monarch:10755 GIPC1

NCBI Gene:10755 GIPC1

OMIM:605072 GIPC1

UCSC:O14908 GIPC1

Reference Transcript

Participates

as a component of

as an input of

Inferred To

Gipc1 [cytoplasm] (Mus musculus)

Gipc1 [cytoplasm] (Rattus norvegicus)

GIPC1 [cytoplasm] (Canis familiaris)

GIPC1 [cytoplasm] (Gallus gallus)

GIPC1 [cytoplasm] (Sus scrofa)

gipc1 [cytoplasm] (Danio rerio)

gipc1 [cytoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_974199.1, XP_016881637.1, NP_974198.1, XP_016881636.1, NP_974223.1, NP_005707.1, NP_974197.1, XP_054175518.1

OpenTargets

ENSG00000123159

ENSEMBL

ENSP00000376753, ENSP00000376748, ENST00000586027, ENSP00000340698, ENST00000345425, ENSP00000466747, ENST00000393028, ENST00000393033, ENST00000591349, ENSP00000467077, ENSG00000123159

HPA

ENSG00000123159-GIPC1

GeneCards

GIPC1

PRO

O14908

Pharos - Targets

O14908

GlyGen

O14908

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P0V3 SH3BP4	1	SH3BP4 [cytosol] (R-HSA-8866227)	0.736	5
UniProt:Q9NZN5 ARHGEF12	1	ARHGEF12 [cytosol] (R-HSA-416560)	0.723	8
UniProt:P06463 VE6			0.69	4
UniProt:Q9UM54 MYO6	3	MYO6 [plasma membrane] (R-HSA-3006691) MYO6 [lysosomal membrane] (R-HSA-3006694) MYO6 [cytosol] (R-HSA-3006692)	0.688	3
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.589	2
UniProt:Q9HB19 PLEKHA2	1	PLEKHA2 [plasma membrane] (R-HSA-8870329)	0.556	3
UniProt:Q03167 TGFBR3	5	TGFBR3_mem [plasma membrane] (R-HSA-9839336) TGFBR3(21-851) [extracellular region] (R-HSA-9839335) TGFBR3(784-851) [basolateral plasma membrane] (R-HSA-9839380) TGFBR3 [cytosol] (R-HSA-9839374) pT841_TGFBR3 [plasma membrane] (R-HSA-9839364)	0.508	3
UniProt:P17643 TYRP1	1	TYRP1 [melanosome membrane] (R-HSA-8878574)	0.508	3
UniProt:Q9C0C4 SEM4C			0.483	2
UniProt:Q8TF65 GIPC2			0.483	2
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.483	3
UniProt:Q8NEU8 DP13B			0.483	3
UniProt:Q9BWT7 CAR10			0.482	2

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