Secreted NS1 binds to other cell

Stable Identifier
R-HSA-9920147
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Dengue virus type 2
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
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Secreted NS1 binds to other cell
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Soluble NS1 binds to the surface of uninfected cells, primarily via interactions with heparan sulfate and chondroitin sulfate E (Avirutnan et al., 2007).
Literature References
PubMed ID Title Journal Year
18052531 Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E

Avirutnan, P, Zhang, L, Punyadee, N, Manuyakorn, A, Puttikhunt, C, Kasinrerk, W, Malasit, P, Atkinson, JP, Diamond, MS

PLoS Pathog 2007
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
protein localization to plasma membrane (0072659)
This event is regulated
Positively by
Regulator
HSPGs [plasma membrane] (Homo sapiens)
Disease
Name Identifier Synonyms
dengue disease DOID:12205 breakbone fever, Dengue Fever, classic dengue
Cross References
Mondo
Authored
Stephan, R  (2024-08-19)
Reviewed
Roque Ascenção, F  (2025-10-29)
Mansur, DS  (2025-10-29)
Created
Stephan, R  (2024-08-29)
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