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FURIN [Golgi membrane]
Stable Identifier
R-MMU-157049
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
Golgi membrane
Synonyms
P23188
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Mus musculus)
Degradation of the extracellular matrix (Mus musculus)
Activation of Matrix Metalloproteinases (Mus musculus)
Activation of MT-MMPs by FURIN (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Activation of proMMP11 by FURIN (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Mus musculus)
FURIN translocates to the plasma membrane (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Mus musculus)
Removal of aminoterminal propeptides from gamma-carboxylated proteins (Mus musculus)
Furin cleaves pro-BGLAP to BGLAP (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-GAS6 to GAS6 (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-factor IX to factor IX (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-factor VII to factor VII (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-factor X to factor X (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-protein C to protein C (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-protein S to protein S (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-protein Z to protein Z (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Furin cleaves pro-prothrombin to prothrombin (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by NOTCH (Mus musculus)
Pre-NOTCH Expression and Processing (Mus musculus)
Pre-NOTCH Processing in Golgi (Mus musculus)
Fringe-modified Pre-NOTCH is cleaved by FURIN (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
NOTCH precursor cleaved to form mature NOTCH (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by PDGF (Mus musculus)
PDGF-AA clevage by Furin (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
PDGF-AB clevage by Furin (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
PDGF-BB clevage by Furin (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Signaling by TGFB family members (Mus musculus)
Signaling by TGF-beta Receptor Complex (Mus musculus)
TGF-beta receptor signaling activates SMADs (Mus musculus)
Latent TGF-beta-1 is cleaved by FURIN (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Mus musculus)
FURIN translocates to the plasma membrane (Mus musculus)
FURIN [Golgi membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:P23188 Furin
Gene Names
Furin, Fur, Pcsk3
Chain
signal peptide:1-24, propeptide:25-107, chain:108-793
Reference Genes
BioGPS Gene:18550 Furin
ENSEMBL:ENSMUSG00000030530.16 Furin
KEGG Gene (Mus musculus):18550 Furin
Monarch:18550 Furin
NCBI Gene:18550 Furin
UCSC:P23188 Furin
Reference Transcript
RefSeq:NM_001081454.2 Furin
RefSeq:NM_011046.3 Furin
Other Identifiers
100515_at
10564960
1418518_at
17492598
18550
4443431
4480172
4514634
4520742
4526462
4537838
4538134
4610732
4662118
4750277
4761202
4779682
4924448
4952833
5065598
5067649
5151119
5166293
5203420
5231241
5243063
5341997
5409546
5473901
5485031
5541039
A_51_P400107
A_55_P2064557
GE42653
GO:0000139
GO:0001825
GO:0002020
GO:0003824
GO:0004175
GO:0004252
GO:0004867
GO:0005515
GO:0005576
GO:0005768
GO:0005769
GO:0005783
GO:0005788
GO:0005789
GO:0005794
GO:0005802
GO:0005886
GO:0006465
GO:0006508
GO:0008201
GO:0008233
GO:0008236
GO:0009966
GO:0009986
GO:0010008
GO:0012510
GO:0016020
GO:0016485
GO:0016486
GO:0016787
GO:0019058
GO:0023052
GO:0030140
GO:0030163
GO:0030335
GO:0030511
GO:0031410
GO:0031638
GO:0031985
GO:0032374
GO:0032804
GO:0032902
GO:0032911
GO:0032940
GO:0042176
GO:0042277
GO:0043043
GO:0043226
GO:0045121
GO:0046598
GO:0046872
GO:0048406
GO:0048856
GO:0048870
GO:0051604
GO:0090472
GO:0097341
GO:0098772
GO:0140096
GO:0140447
GO:1904399
ILMN_1252364
ILMN_3069914
ILMN_3148489
l26489_s_at
mMC023954
Participates
as an input of
FURIN translocates to the plasma membrane (Mus musculus)
Other forms of this molecule
FURIN [Golgi lumen]
FURIN [plasma membrane]
Furin [extracellular region]
FURIN [extracellular region]
Furin [endoplasmic reticulum lumen]
Inferred From
FURIN [Golgi membrane]
(Homo sapiens)
Cross References
RefSeq
NP_035176.1
,
NP_001074923.1
Ensembl
ENSMUST00000120753
,
ENSMUSP00000113793
,
ENSMUSP00000102985
,
ENSMUSG00000030530
,
ENSMUST00000122232
,
ENSMUSP00000113370
,
ENSMUST00000107362
PRO
P23188
MGI
97513
PDB
1P8J
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