Reactome | Prr5 [cytosol]

Prr5 [cytosol]

Stable Identifier

R-MMU-6795323

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

PRR5, Q812A5

Locations in the PathwayBrowser

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Cellular responses to stimuli (Mus musculus)

- Cellular responses to mechanical stimuli (Mus musculus)
  - Response of endothelial cells to shear stress (Mus musculus)
    - High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Mus musculus)
      - mTORC2 phosphorylates AKT1 on serine-473 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        Prr5 [cytosol] (Mus musculus)

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - Regulation of TP53 Activity (Mus musculus)
        
        Regulation of TP53 Expression and Degradation (Mus musculus)
        
        Regulation of TP53 Degradation (Mus musculus)
        
        mTORC2 phosphorylates SGK1 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        Prr5 [cytosol] (Mus musculus)

Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Regulation of T cell activation by CD28 family (Mus musculus)
    - Co-stimulation by CD28 (Mus musculus)
      - CD28 dependent PI3K/Akt signaling (Mus musculus)
        
        mTORC2 phosphorylates AKT at S473 (Mus musculus)
        
        mTORC2:PIP3 [plasma membrane] (Mus musculus)
        
        Prr5 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q812A5

Gene Names

Prr5

Reference Genes

BioGPS Gene:109270 Prr5

ENSEMBL:ENSMUSG00000036106

KEGG:mmu:109270 Prr5

Monarch:109270 Prr5

NCBI Gene:109270 Prr5

UCSC:Q812A5 Prr5

Reference Transcript

Other Identifiers

103511_at

10425880

109270

1451463_at

17313739

4713972

4827014

5139950

5158290

5170853

5231717

5237198

5317999

5386593

5475239

5543770

5573261

5587639

A_52_P145482

A_55_P2078204

GO:0005096

GO:0007010

GO:0030036

GO:0030307

GO:0030335

GO:0031669

GO:0031932

GO:0038203

GO:0043066

GO:0043491

GO:0051897

GO:0098772

ILMN_2653275

ILMN_2723509

ILMN_2977350

c78947_rc_at

Participates

as a component of

mTORC2:PIP3 [plasma membrane] (Mus musculus)

Inferred From

PRR5 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_666173.4, XP_006520344.1, NP_001333591.1, XP_030104132.1

ENSEMBL

ENSMUSP00000127890, ENSMUST00000171460, ENSMUST00000065499, ENSMUSP00000066396, ENSMUSG00000036106

PRO

Q812A5

MGI

1924714

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