Reactome | TFAP2C [nucleoplasm]

TFAP2C [nucleoplasm]

Stable Identifier

R-SSC-3234071

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

monoSUMO1-K10-TFAP2C, A5GFZ9

Locations in the PathwayBrowser

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Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - Generic Transcription Pathway (Sus scrofa)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Sus scrofa)
      - Negative regulation of activity of TFAP2 (AP-2) family transcription factors (Sus scrofa)
        
        SUMOylation of TFAP2C with SUMO1 (Sus scrofa)
        
        SUMO1:TFAP2C homodimer [nucleoplasm] (Sus scrofa)
        
        TFAP2C [nucleoplasm] (Sus scrofa)

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - SUMOylation (Sus scrofa)
    - SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
      - SUMOylation of transcription factors (Sus scrofa)
        
        SUMOylation of TFAP2C with SUMO1 (Sus scrofa)
        
        SUMO1:TFAP2C homodimer [nucleoplasm] (Sus scrofa)
        
        TFAP2C [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A5GFZ9

Gene Names

TFAP2C

Reference Genes

BioGPS Gene:100144525 TFAP2C

ENSEMBL:ENSSSCG00000007499.3

KEGG:ssc:100144525 TFAP2C

Monarch:100144525 TFAP2C

NCBI Gene:100144525 TFAP2C

UCSC:A5GFZ9 TFAP2C

Reference Transcript

RefSeq:NM_001123201.1 TFAP2C

Other Identifiers

100144525

GO:0000122

GO:0000977

GO:0000978

GO:0000981

GO:0001227

GO:0001228

GO:0001826

GO:0001829

GO:0001942

GO:0003334

GO:0003677

GO:0003700

GO:0005634

GO:0005654

GO:0005739

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0008584

GO:0019827

GO:0021877

GO:0021987

GO:0030154

GO:0030718

GO:0030855

GO:0035019

GO:0042127

GO:0043588

GO:0045682

GO:0045814

GO:0045944

GO:0048733

GO:0048856

GO:0048863

GO:0060598

GO:0060750

GO:0140001

GO:1990837

Ssc.1426.1.S1_at

Participates

as a component of

SUMO1:TFAP2C homodimer [nucleoplasm] (Sus scrofa)

Other forms of this molecule

TFAP2C [cytosol]

TFAP2C [nucleoplasm]

Inferred From

monoSUMO1-K10-TFAP2C [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 10 (in Homo sapiens)

Coordinate

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_001116673.1

ENSEMBL

ENSSSCG00000007499, ENSSSCT00000008209, ENSSSCP00000007991

VGNC

95540

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