Reactome | SYT1 [clathrin-coated endocytic vesicle membrane]

SYT1 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-CEL-8869113

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

P34693

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - Clathrin-mediated endocytosis (Caenorhabditis elegans)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
    - RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        STON2,1:SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT dimers [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        SYT1 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P34693

Reference Genes

BioGPS Gene:174120

CTD Gene:174120

ENSEMBL:WBGene00004921

KEGG:cel:CELE_F31E8.2

Monarch:174120

NCBI Gene:174120

UCSC:P34693

Wormbase:WBGene00004921

Reference Transcript

RefSeq:NM_001026958.6

Other Identifiers

174120

GO:0000149

GO:0005509

GO:0005544

GO:0005886

GO:0007626

GO:0008021

GO:0012501

GO:0016020

GO:0016079

GO:0016192

GO:0017158

GO:0022600

GO:0030421

GO:0030424

GO:0030672

GO:0031045

GO:0031410

GO:0043051

GO:0045202

GO:0046872

GO:0046928

GO:0048488

GO:0061891

GO:0070266

GO:0070382

GO:0099502

GO:2000300

Participates

as a component of

SYT1 dimer [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

Other forms of this molecule

SYT2 [clathrin-coated endocytic vesicle membrane]

SYT8 [clathrin-coated endocytic vesicle membrane]

SYT8 [plasma membrane]

SYT2 [plasma membrane]

SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane]

SYT1 [clathrin-sculpted glutamate transport vesicle membrane]

SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]

SYT1 [plasma membrane]

SYT1 [clathrin-sculpted monoamine transport vesicle membrane]

Inferred From

SYT1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001022129.1

ENSEMBL

F31E8.2a.1, WBGene00004921, F31E8.2a.1

PRO

P34693