Reactome | phospho-ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

Stable Identifier

R-DRE-873798-5

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

p-Y457-IFNGR1, D9IL84

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Interferon Signaling (Danio rerio)
    - Interferon gamma signaling (Danio rerio)
      - Binding of STAT1 to p-IFNGR1 (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
      - IFNG signaling activates MAPKs (Danio rerio)
        
        Activated JAK1 binds RAF1 (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        JAK1-activated RAF1 phosphorylates MAPKs (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        JAK1-mediated phosphorylation of RAF1 (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
      - Phosphorylation of IFNGR1 by JAK kinases (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
      - Phosphorylation of STAT1 at Ser727 (Danio rerio)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
      - Phosphorylation of STAT1 by JAK kinases (Danio rerio)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
      - Release of STAT1 dimer from active receptor unit (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Danio rerio)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Danio rerio)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Danio rerio)
        
        Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)
        
        phospho-ifnlr1 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:D9IL84

Gene Names

ifnlr1

Reference Genes

BioGPS Gene:100332149 ifnlr1

ENSEMBL:ENSDARG00000087131

Monarch:100332149 ifnlr1

NCBI Gene:100332149 ifnlr1

UCSC:D9IL84 ifnlr1

Reference Transcript

RefSeq:NM_001197202.2 ifnlr1

Participates

as a member of

Homologues of p-Y457-IFNGR1 [plasma membrane] (Danio rerio)

Other forms of this molecule

ifnlr1 [extracellular region]

ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

ifnlr1 [plasma membrane]

phospho-ifnlr1 [plasma membrane]

ifnlr1 [plasma membrane]

Inferred From

p-Y457-IFNGR1 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 457 (in Homo sapiens)

Coordinate

457

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001184131.1

ZFIN

ZDB-GENE-071120-5

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