Reactome | rnf185 [endoplasmic reticulum membrane]

rnf185 [endoplasmic reticulum membrane]

Stable Identifier

R-DRE-8861819

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

endoplasmic reticulum membrane

Synonyms

RNF185, Q6PC78

Locations in the PathwayBrowser

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Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - Regulation of T cell activation by CD28 family (Danio rerio)
    - Co-inhibition by PD-1 (Danio rerio)
      - Regulation of PD-L1(CD274) expression (Danio rerio)
        
        Regulation of PD-L1(CD274) Post-translational modification (Danio rerio)
        
        AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Danio rerio)
        
        Ubiquitination of CD274 by ERAD complex (Danio rerio)
        
        ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        rnf185 [endoplasmic reticulum membrane] (Danio rerio)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        rnf185 [endoplasmic reticulum membrane] (Danio rerio)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
        
        rnf185 [endoplasmic reticulum membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6PC78

Gene Names

rnf185

Reference Genes

BioGPS Gene:406310 rnf185

ENSEMBL:ENSDARG00000032997

KEGG:dre:406310 rnf185

Monarch:406310 rnf185

NCBI Gene:406310 rnf185

UCSC:Q6PC78 rnf185

Reference Transcript

RefSeq:NM_213037.1 rnf185

Other Identifiers

13201137

406310

A_15_P461210

A_15_P630096

BC059445.1

DRER05685

Dr.11136.1.S1_at

ENSDART00000046781

ENSDART00000046781_1

ENSDART00000046781_2

GO:0003824

GO:0005783

GO:0006511

GO:0016740

GO:0046872

GO:0061630

GO:0140096

LOLS11807

MADDr01001973

NM_213037

Participates

as a component of

ERAD complex [endoplasmic reticulum membrane] (Danio rerio)

Inferred From

RNF5,RNF185 [endoplasmic reticulum membrane] (Homo sapiens)

RNF185 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_998202.1

ENSEMBL

ENSDARG00000032997, ENSDARP00000046780, ENSDART00000046781

IntEnz

2.3.2.27

ZFIN

ZDB-GENE-040426-1977

PRO

Q6PC78