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phospho-p-S317,S345-CHEK1 [nucleoplasm]
Stable Identifier
R-GGA-113838
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
Q8AYC9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Gallus gallus)
Cell Cycle Checkpoints (Gallus gallus)
G1/S DNA Damage Checkpoints (Gallus gallus)
p53-Independent G1/S DNA Damage Checkpoint (Gallus gallus)
Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A (Gallus gallus)
CHEK1 phosphorylates CHEK2-phosphorylated CDC25A (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
Phosphorylation of CDC25A by CHEK1 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
G2/M Checkpoints (Gallus gallus)
Activation of ATR in response to replication stress (Gallus gallus)
Phosphorylation of CDC25A by CHEK1 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
Recruitment and activation of Chk1 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
G2/M DNA damage checkpoint (Gallus gallus)
Recruitment and activation of Chk1 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
DNA Repair (Gallus gallus)
DNA Double-Strand Break Repair (Gallus gallus)
Homology Directed Repair (Gallus gallus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Gallus gallus)
HDR through Homologous Recombination (HRR) (Gallus gallus)
Homologous DNA Pairing and Strand Exchange (Gallus gallus)
Presynaptic phase of homologous DNA pairing and strand exchange (Gallus gallus)
CHEK1 phosphorylates RAD51 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
Processing of DNA double-strand break ends (Gallus gallus)
Activation of CHEK1 at resected DNA DSBs (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by E2F6 (Gallus gallus)
CHEK1 phosphorylates E2F6 (Gallus gallus)
phospho-p-S317,S345-CHEK1 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8AYC9 CHEK1
Gene Names
CHEK1, CHK1
Chain
chain:1-476
Reference Genes
BioGPS Gene:374260 CHEK1
KEGG:gga:374260 CHEK1
Monarch:374260 CHEK1
NCBI Gene:374260 CHEK1
UCSC:Q8AYC9 CHEK1
Reference Transcript
RefSeq:NM_204345.2 CHEK1
Other Identifiers
374260
GO:0000077
GO:0000086
GO:0000166
GO:0000228
GO:0000781
GO:0000785
GO:0000794
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006281
GO:0006325
GO:0006338
GO:0006468
GO:0006915
GO:0006974
GO:0006997
GO:0006998
GO:0007077
GO:0007095
GO:0010468
GO:0010569
GO:0010971
GO:0016301
GO:0016740
GO:0018107
GO:0019904
GO:0032991
GO:0035402
GO:0042127
GO:0042770
GO:0044818
GO:0045787
GO:0045814
GO:0045839
GO:0046602
GO:0061024
GO:0071260
GO:0106310
GO:0140096
GO:1902742
GT_A_87_P016242
GT_A_87_P064741
GT_A_87_P193448
Gga.11916.1.S1_at
Gga.4288.1.S1_at
Participates
as an output of
Recruitment and activation of Chk1 (Gallus gallus)
Activation of CHEK1 at resected DNA DSBs (Gallus gallus)
Other forms of this molecule
phospho-STT3 [nucleoplasm]
STT3 [nucleoplasm]
CHEK1 [cytosol]
CHEK1 [nucleoplasm]
Inferred From
p-S317,S345-CHEK1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 317 (in Homo sapiens)
Coordinate
317
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 345
Coordinate
345
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_989676.1
ENSEMBL
ENSGALT00010058076
,
ENSGALP00010035254
,
ENSGALG00010023828
PRO
Q8AYC9
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