Reactome | phospho-IFNGR1 [plasma membrane]

phospho-IFNGR1 [plasma membrane]

Stable Identifier

R-GGA-873798

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

p-Y457-IFNGR1, A0A8V0XK86

Locations in the PathwayBrowser

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Immune System (Gallus gallus)

- Cytokine Signaling in Immune system (Gallus gallus)
  - Interferon Signaling (Gallus gallus)
    - Interferon gamma signaling (Gallus gallus)
      - Binding of STAT1 to p-IFNGR1 (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
      - IFNG signaling activates MAPKs (Gallus gallus)
        
        Activated JAK1 binds RAF1 (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        JAK1-activated RAF1 phosphorylates MAPKs (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        JAK1-mediated phosphorylation of RAF1 (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
      - Phosphorylation of IFNGR1 by JAK kinases (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
      - Phosphorylation of STAT1 at Ser727 (Gallus gallus)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
      - Phosphorylation of STAT1 by JAK kinases (Gallus gallus)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
      - Release of STAT1 dimer from active receptor unit (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Gallus gallus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Gallus gallus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)
        
        phospho-IFNGR1 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0XK86

Gene Names

IFNGR1

Reference Genes

ENSEMBL:ENSGALG00010005291.1

UCSC:A0A8V0XK86 IFNGR1

Other Identifiers

421685

GO:0004896

GO:0005515

GO:0016020

GO:0019955

GT_A_87_P017945

GT_A_87_P098976

GT_A_87_P225858

GT_Sp_Chicken_CO763843_8458

Gga.9134.1.S1_at

Participates

as a component of

p-IFNGR1:p-JAK1 [plasma membrane] (Gallus gallus)

Other forms of this molecule

IFNGR1 [plasma membrane]

Inferred From

p-Y457-IFNGR1 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 457 (in Homo sapiens)

Coordinate

457

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

ENSEMBL

ENSGALT00010012544, ENSGALG00010005291, ENSGALP00010007108

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