Cytosolic PLK1 translocates to the nucleus

Stable Identifier
R-HSA-3002798
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
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Cytosolic PLK1 translocates to the nucleus
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PLK1 is induced in S phase and can be find in both cytosol and nucleus in S and G2 phases of the cell cycle. PLK1 possesses a bipartite nuclear localization signal (NLS) that enables it to enter the nucleus (Taniguchi et al. 2002).

Literature References
PubMed ID Title Journal Year
12364337 Nuclear translocation of plk1 mediated by its bipartite nuclear localization signal

Taniguchi, E, Toyoshima-Morimoto, F, Nishida, E

J. Biol. Chem. 2002
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Orthologous Events
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Cytosolic PLK1 translocates to the nucleus (Drosophila melanogaster)
Cytosolic PLK1 translocates to the nucleus (Gallus gallus)
Cytosolic PLK1 translocates to the nucleus (Mus musculus)
Cytosolic PLK1 translocates to the nucleus (Plasmodium falciparum)
Cytosolic PLK1 translocates to the nucleus (Rattus norvegicus)
Cytosolic PLK1 translocates to the nucleus (Saccharomyces cerevisiae)
Cytosolic PLK1 translocates to the nucleus (Schizosaccharomyces pombe)
Cytosolic PLK1 translocates to the nucleus (Sus scrofa)
Cytosolic PLK1 translocates to the nucleus (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2013-01-29)
Reviewed
Weil, R  (2013-02-07)
Created
Orlic-Milacic, M  (2013-01-28)
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