Reactome | NFYB [nucleoplasm]

NFYB [nucleoplasm]

Stable Identifier

R-HSA-381067

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

NF-YB

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P25208 NFYB

Gene Names

NFYB, HAP3

Chain

chain:1-207

Reference Genes

BioGPS Gene:4801 NFYB

COSMIC (genes):NFYB NFYB

CTD Gene:4801 NFYB

dbSNP Gene:4801 NFYB

ENSEMBL:ENSG00000120837 NFYB

ENSEMBL_homo_sapiens_GENE:ENSG00000120837.8 NFYB

HGNC:7805 NFYB

KEGG Gene (Homo sapiens):4801 NFYB

Monarch:4801 NFYB

NCBI Gene:4801 NFYB

OMIM:189904 NFYB

UCSC:P25208 NFYB

Reference Transcript

RefSeq:NM_006166.3 NFYB

Other Identifiers

11733065_a_at

11733066_at

11733067_at

16769443

218127_PM_at

218127_at

218128_PM_at

218128_at

218129_PM_s_at

218129_s_at

244704_PM_at

244704_at

2688281

3468927

3468928

3468929

3468930

3468931

3468932

3468933

3468934

3468936

3468937

3468940

3468941

3468944

3468947

3468948

3468949

3468950

37928_at

4801

52749_at

64685_at

72474_at

7965956

A_23_P314591

A_23_P53668

GE59848

GO:0000785

GO:0000976

GO:0000978

GO:0000981

GO:0001228

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0016602

GO:0032993

GO:0035065

GO:0036211

GO:0043226

GO:0043565

GO:0045893

GO:0045944

GO:0046982

GO:0090575

GO:0140110

GO:0140297

GO:1990830

HMNXSV003021742

Hs.225706.0.A1_3p_at

Hs.84928.0.S3_3p_at

Hs.84928.0.S4_3p_at

Hs.84928.0.S4_3p_x_at

ILMN_1668726

PH_hs_0031375

TC12001906.hg

X59710_at

g11496976_3p_a_at

Participates

as a component of

NF-Y [nucleoplasm] (Homo sapiens)

Inferred To

Nf-YB [nucleoplasm] (Drosophila melanogaster)

nfyB [nucleoplasm] (Dictyostelium discoideum)

Nfyb [nucleoplasm] (Mus musculus)

Nfyb [nucleoplasm] (Rattus norvegicus)

HAP3 [nucleoplasm] (Saccharomyces cerevisiae)

NFYB [nucleoplasm] (Bos taurus)

NFYB [nucleoplasm] (Canis familiaris)

NFYB [nucleoplasm] (Gallus gallus)

NFYB [nucleoplasm] (Sus scrofa)

Homologues of NFYB [nucleoplasm] (Bos taurus)

nfyb-1 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006157.1

OpenTargets

ENSG00000120837

GeneCards

P25208

HPA

ENSG00000120837-NFYB

Ensembl

ENST00000551727, ENST00000240055, ENSP00000447486, ENSG00000120837, ENSP00000240055

PRO

P25208

Pharos - Targets

P25208

PDB

4CSR, 8QU3, 7AH8, 1N1J, 6QMS, 6QMP, 6QMQ, 4AWL, 8QU4, 8QU2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.564	6
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3

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