Reactome | IL13RA1 binds TYK2

IL13RA1 binds TYK2

Stable Identifier

R-HSA-6785762

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

ReviewStatus

5/5

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Interleukin-13 receptor subunit alpha-1 (IL13RA1) constitutively associates with Non-receptor tyrosine-protein kinase 2 (TYK2) (Umeshita-Suyama et al. 2000, Roy et al. 2002, LaPorte et al. 2008, Bhattacharjee et al. 2013).

Literature References

PubMed ID	Title	Journal	Year
11058569	Characterization of IL-4 and IL-13 signals dependent on the human IL-13 receptor alpha chain 1: redundancy of requirement of tyrosine residue for STAT3 activation Umeshita-Suyama, R, Sugimoto, R, Akaiwa, M, Arima, K, Yu, B, Wada, M, Kuwano, M, Nakajima, K, Hamasaki, N, Izuhara, K	Int. Immunol.	2000
23124025	IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages Bhattacharjee, A, Shukla, M, Yakubenko, VP, Mulya, A, Kundu, S, Cathcart, MK	Free Radic. Biol. Med.	2013