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AKR1C1 [cytosol]
Stable Identifier
R-RNO-2855253-3
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
A0A8J8YPV6
Locations in the PathwayBrowser
Expand all
Drug ADME (Rattus norvegicus)
Prednisone ADME (Rattus norvegicus)
AKR1C1 hydrogenates PREDN,PREDL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of fat-soluble vitamins (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
AKR1C3 reduces atRAL to atROL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A8J8YPV6
Reference Genes
ENSEMBL:ENSRNOG00000063788
UCSC:A0A8J8YPV6
Other Identifiers
10796043
1398612_at
17716731
361266
5645077
5649136
5684520
5692828
5695132
5770115
5914963
5921195
5945349
5955395
5961616
6012693
6067989
6092655
6167094
6266440
6300047
6337344
6354352
6396943
6422265
6513727
6630867
6652521
6679490
6705583
6716276
A_44_P447957
A_64_P006593
GE1223565
GO:0004032
GO:0005829
GO:0006629
GO:0006693
GO:0016491
GO:0032052
GO:0042448
GO:0044597
GO:0044598
GO:0047023
GO:0047086
GO:1901135
ILMN_1370818
PH_rn_0024100
rc_AI639479_at
Participates
as a member of
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Inferred From
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSRNOT00000041925
,
ENSRNOP00000042421
,
ENSRNOG00000062679
RGD
1308232
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