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AKR1C1 [cytosol]
Stable Identifier
R-RNO-2855253-7
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P51652
Locations in the PathwayBrowser
Expand all
Drug ADME (Rattus norvegicus)
Prednisone ADME (Rattus norvegicus)
AKR1C1 hydrogenates PREDN,PREDL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Rattus norvegicus)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Rattus norvegicus)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Rattus norvegicus)
Aldo-keto reductase family [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of fat-soluble vitamins (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
Retinoid metabolism and transport (Rattus norvegicus)
AKRs reduce RBP2:atRAL to RBP2:atROL (Rattus norvegicus)
AKRs [cytosol] (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
RA biosynthesis pathway (Rattus norvegicus)
AKR1C3 reduces atRAL to atROL (Rattus norvegicus)
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
AKR1C1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P51652
Reference Genes
BioGPS Gene:171516
ENSEMBL:ENSRNOG00000017531
ENSEMBL:ENSRNOG00055018391
ENSEMBL:ENSRNOG00060015960
ENSEMBL:ENSRNOG00065003624
KEGG:rno:171516
Monarch:171516
NCBI Gene:171516
UCSC:P51652
Reference Transcript
RefSeq:NM_138510.1
Other Identifiers
10796061
1387958_at
171516
17716754
5618343
5718701
5745943
5785576
5821866
5882905
5955853
5960085
5967896
6196271
6259066
6526017
6619961
6652474
A_43_P13282
A_64_P042127
E06822cds_s_at
GE19651
GO:0006629
GO:0006709
GO:0007567
GO:0016491
GO:0022414
GO:0047006
L32601_s_at
Participates
as a member of
Homologues of AKR1C1 [cytosol] (Rattus norvegicus)
Inferred From
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_612519.1
ENSEMBL
ENSRNOT00000023739
,
ENSRNOG00000017531
,
ENSRNOP00000023739
IntEnz
1.1.1.149
PRO
P51652
RGD
708428
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