Reactome | phospho-Ifngr1 [plasma membrane]

phospho-Ifngr1 [plasma membrane]

Stable Identifier

R-RNO-873798

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

p-Y457-IFNGR1, F7FHZ1

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Interferon Signaling (Rattus norvegicus)
    - Interferon gamma signaling (Rattus norvegicus)
      - Binding of STAT1 to p-IFNGR1 (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
      - IFNG signaling activates MAPKs (Rattus norvegicus)
        
        Activated JAK1 binds RAF1 (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:RAF1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2:p-Y-RAF1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
      - Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
      - Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
      - Phosphorylation of STAT1 by JAK kinases (Rattus norvegicus)
        
        STAT1 bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        p-STAT1(Y701) bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
      - Release of STAT1 dimer from active receptor unit (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)
        
        p-STAT1 dimer bound to p-IFNGR1 [plasma membrane] (Rattus norvegicus)
        
        IFNG:p-IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:pJAK1:IFNGR2:p-JAK2 [plasma membrane] (Rattus norvegicus)
        
        p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)
        
        phospho-Ifngr1 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:F7FHZ1

Gene Names

Ifngr1

Reference Genes

BioGPS Gene:116465 Ifngr1

ENSEMBL:ENSRNOG00000012074

KEGG:rno:116465 Ifngr1

Monarch:116465 Ifngr1

NCBI Gene:116465 Ifngr1

UCSC:F7FHZ1 Ifngr1

Reference Transcript

RefSeq:NM_053783.3 Ifngr1

Other Identifiers

10701924

116465

1369956_at

17610659

5643664

5929487

6453274

6473667

6546019

6603782

6646183

6661519

6704499

A_42_P658552

A_44_P245530

GE21481

GO:0004896

GO:0005515

GO:0016020

GO:0019955

GO:0060333

ILMN_1366851

PH_rn_0014801

U68272_at

rc_AI233970_at

Participates

as a component of

p-IFNGR1:p-JAK1 [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

Ifngr1 [plasma membrane]

Inferred From

p-Y457-IFNGR1 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 457 (in Homo sapiens)

Coordinate

457

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_446235.3

ENSEMBL

ENSRNOP00000016286, ENSRNOG00000012074, ENSRNOT00000016286

RGD

620570

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