Reactome | FCGR2B [plasma membrane]

FCGR2B [plasma membrane]

Stable Identifier

R-HSA-197854

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Low affinity immunoglobulin gamma Fc region receptor II-b precursor, FCGB_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P31994 FCGR2B

Gene Names

FCGR2B, CD32, FCG2, IGFR2

Chain

signal peptide:1-42, chain:43-310

Reference Genes

BioGPS Gene:2213 FCGR2B

COSMIC - genes:FCGR2B FCGR2B

CTD Gene:2213 FCGR2B

dbSNP Gene:2213 FCGR2B

ENSEMBL:ENSG00000072694 FCGR2B

HGNC:3618 FCGR2B

KEGG:hsa:2213 FCGR2B

Monarch:2213 FCGR2B

NCBI Gene:2213 FCGR2B

OMIM:604590 FCGR2B

UCSC:P31994 FCGR2B

Reference Transcript

Other Identifiers

11726046_s_at

11741517_s_at

11741518_x_at

11741899_s_at

16672920

210889_PM_s_at

210889_s_at

211395_PM_x_at

211395_x_at

2213

2363745

2363746

2363755

2363758

2363817

2363818

2363819

2363820

2363821

2363822

2363823

2363829

2363830

2363831

2363832

2363833

2363836

2363837

2363838

2363839

2363840

2363841

2363842

2363843

2363844

2363846

2363847

2363848

2363849

34663_at

34664_at

34665_g_at

7906767

7906777

A_23_P34644

A_24_P938284

A_33_P3327617

GE80163

GO:0001540

GO:0001788

GO:0001811

GO:0001814

GO:0001818

GO:0002252

GO:0002266

GO:0002313

GO:0002316

GO:0002376

GO:0002436

GO:0002605

GO:0002622

GO:0002638

GO:0002682

GO:0002819

GO:0002865

GO:0002922

GO:0002924

GO:0005515

GO:0005886

GO:0006898

GO:0006909

GO:0006911

GO:0006952

GO:0006954

GO:0007166

GO:0009617

GO:0009897

GO:0016020

GO:0016064

GO:0016192

GO:0019770

GO:0019772

GO:0019864

GO:0019886

GO:0021549

GO:0030889

GO:0032693

GO:0032760

GO:0038094

GO:0043031

GO:0043197

GO:0043318

GO:0044297

GO:0044877

GO:0045088

GO:0046330

GO:0048856

GO:0050765

GO:0050766

GO:0050777

GO:0050859

GO:0050869

GO:0061024

GO:0071219

GO:0090264

GO:1902564

GO:1902950

GO:1903381

GO:1904646

GO:1905898

GO:2001199

HMNXSV003048056

ILMN_1660027

ILMN_1804174

ILMN_2382403

PH_hs_0038256

TC01006338.hg

X62573_at

g182598_3p_a_at

g182598_3p_x_at

Participates

as a member of

Lymphoid-expressed Fc-gamma receptors [plasma membrane] (Homo sapiens)

Inferred To

Fcgr2 [plasma membrane] (Mus musculus)

Fcgr2 [plasma membrane] (Rattus norvegicus)

LOC110260307 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_001002275.1, NP_001177757.1, NP_003992.3, NP_001002273.1, NP_001002274.1, NP_001381406.1

ENSEMBL

ENSG00000072694, ENST00000236937, ENST00000358671, ENSP00000351497, ENST00000367961, ENSP00000356938, ENSP00000236937

OpenTargets

ENSG00000072694

GeneCards

FCGR2B

HPA

ENSG00000072694-FCGR2B

PRO

P31994

Pharos - Targets

P31994

GlyGen

P31994

Orphanet

FCGR2B

PDB

2FCB, 5OCC, 3WJJ

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92835 INPP5D	2	INPP5D [cytosol] (R-HSA-197940) p-Y-INPP5D [cytosol] (R-HSA-9680730)	0.702	3
UniProt:P29350 PTPN6	5	PTPN6 [cytosol] (R-HSA-197938) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [specific granule lumen] (R-HSA-6799641)	0.669	3
UniProt:P19174 PLCG1	6	p-4Y-PLCG1 [plasma membrane] (R-HSA-167679) PLCG1 [cytosol] (R-HSA-202320) PLCG1 [plasma membrane] (R-HSA-167682) p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-HSA-202357) p-Y771,Y783-PLCG1 [plasma membrane] (R-HSA-1169084) p-Y-PLCG1 [cytosol] (R-HSA-9029082)	0.544	2