Reactome | TARBP2 [cytosol]

TARBP2 [cytosol]

Stable Identifier

R-HSA-203864

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

TRBP

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15633 TARBP2

Gene Names

TARBP2, TRBP

Chain

chain:1-366

Reference Genes

BioGPS Gene:6895 TARBP2

COSMIC (genes):TARBP2 TARBP2

CTD Gene:6895 TARBP2

dbSNP Gene:6895 TARBP2

ENSEMBL:ENSG00000139546 TARBP2

ENSEMBL_homo_sapiens_GENE:ENSG00000139546.12 TARBP2

HGNC:11569 TARBP2

KEGG Gene (Homo sapiens):6895 TARBP2

Monarch:6895 TARBP2

NCBI Gene:6895 TARBP2

OMIM:605053 TARBP2

UCSC:Q15633 TARBP2

Reference Transcript

Other Identifiers

11721160_a_at

16751857

203677_PM_s_at

203677_s_at

3110430

3416115

3416116

3416117

3416118

3416119

3416120

3416121

3416123

3416126

3416127

3416130

3416133

3416134

3416136

3416139

3416141

3416142

3416143

3416144

3416145

35657_at

6895

7955829

A_14_P116744

A_23_P87603

GE58899

GO:0002376

GO:0003723

GO:0003725

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006417

GO:0006469

GO:0016442

GO:0016604

GO:0019899

GO:0023052

GO:0030422

GO:0031047

GO:0031054

GO:0035196

GO:0035197

GO:0035198

GO:0036002

GO:0036211

GO:0039532

GO:0042802

GO:0042803

GO:0043226

GO:0045070

GO:0046782

GO:0048471

GO:0050689

GO:0065003

GO:0070578

GO:0070883

GO:0070920

GO:0070921

GO:0070922

GO:0098542

GO:0098795

GO:0140311

GO:0140313

GO:1903798

HMNXSV003034599

ILMN_1729767

PH_hs_0000039

PH_hs_0035310

TC12000440.hg

U08998_at

g7427525_3p_s_at

Participates

as a component of

Other forms of this molecule

p-TARBP2 [cytosol]

Inferred To

r2d2 [cytosol] (Drosophila melanogaster)

DIP1 [cytosol] (Drosophila melanogaster)

Tarbp2 [cytosol] (Mus musculus)

Tarbp2 [cytosol] (Rattus norvegicus)

TARBP2 [cytosol] (Bos taurus)

TARBP2 [cytosol] (Canis familiaris)

TARBP2 [cytosol] (Gallus gallus)

TARBP2 [cytosol] (Sus scrofa)

rde-4 [cytosol] (Caenorhabditis elegans)

loqs [cytosol] (Drosophila melanogaster)

blanks [cytosol] (Drosophila melanogaster)

Homologues of TARBP2 [cytosol] (Drosophila melanogaster)

tarbp2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

XP_005269172.1, NP_004169.3, XP_005269171.1, NP_599151.2, NP_599150.1

OpenTargets

ENSG00000139546

HPA

ENSG00000139546-TARBP2

GeneCards

Q15633

Ensembl

ENST00000266987, ENSP00000377885, ENSG00000139546, ENST00000456234, ENSP00000416077, ENSP00000266987, ENST00000394357

PRO

Q15633

Pharos - Targets

Q15633

PDB

5ZAL, 3LLH, 4WYQ, 5N8L, 5ZAM, 2CPN, 3ADL, 5ZAK, 6ZBK, 5N8M

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UPY3 DICER1	1	DICER1 [cytosol] (R-HSA-203820)	0.956	25
UniProt:Q9UKV8 AGO2	2	AGO2 [nucleoplasm] (R-HSA-5578701) AGO2 [cytosol] (R-HSA-209723)	0.932	12
UniProt:O75569 PRKRA	2	p-S246,S287-PRKRA [cytosol] (R-HSA-9834791) PRKRA [cytosol] (R-HSA-2399897)	0.919	15
UniProt:Q9UPY3-1 DICER1			0.778	5
UniProt:Q15633 TARBP2	2	TARBP2 [cytosol] (R-HSA-203864) p-TARBP2 [cytosol] (R-HSA-9835348)	0.742	5
UniProt:Q9UL40 ZN346			0.718	6
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.697	5
UniProt:Q96SI9 STRBP			0.666	4
UniProt:Q9UL18 AGO1	2	EIF2C1 [nucleoplasm] (R-HSA-5578686) EIF2C1 [cytosol] (R-HSA-210616)	0.643	5
UniProt:Q8N8B7 TEANC			0.556	3
UniProt:Q9H898-2 ZMAT4			0.556	3
UniProt:Q15560 TCEA2			0.556	3
UniProt:Q96T60 PNKP	1	PNKP [nucleoplasm] (R-HSA-5649651)	0.556	3
UniProt:Q8N8B7-2 TCEANC			0.556	3
UniProt:Q9HA38 ZMAT3			0.556	3
UniProt:P78563-4 ADARB1			0.556	3
UniProt:P03496 NS	2	NS1 [nucleoplasm] (R-FLU-169113) NS1 [cytosol] (R-FLU-169118)	0.553	2
IntAct:EBI-11167928 DS			0.544	2
UniProt:Q9Y6A4 CFA20			0.508	2
UniProt:P55265-5 ADAR			0.499	3
UniProt:P19525 EIF2AK2	5	p-EIF2AK2 [nucleoplasm] (R-HSA-9836332) SUMO-EIF2AK2 [cytosol] (R-HSA-9834829) ISG15-EIF2AK2 [cytosol] (R-HSA-9833968) p-EIF2AK2 [cytosol] (R-HSA-9833834) EIF2AK2 [cytosol] (R-HSA-168699)	0.499	2
UniProt:Q6ZVK8 NUDT18			0.488	2
UniProt:Q12906 ILF3	3	p-T188,T315-ILF3 [cytosol] (R-HSA-9836381) ILF3 [cytosol] (R-HSA-450564) ILF3 [nucleoplasm] (R-HSA-9760401)	0.483	2

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