Heparan(1)-GPC3 [Golgi lumen]

Stable Identifier
R-HSA-2076279
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
GPC3, Glypican-3, GPC3_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P51654 GPC3
Gene Names
GPC3, OCI5
Chain
signal peptide:1-24, chain:25-358, chain:359-554, propeptide:555-580
Reference Genes
BioGPS Gene:2719 GPC3
COSMIC (genes):GPC3 GPC3
CTD Gene:2719 GPC3
dbSNP Gene:2719 GPC3
ENSEMBL:ENSG00000147257 GPC3
ENSEMBL_homo_sapiens_GENE:ENSG00000147257.16 GPC3
HGNC:4451 GPC3
KEGG Gene (Homo sapiens):2719 GPC3
Monarch:2719 GPC3
NCBI Gene:2719 GPC3
OMIM:300037 GPC3
UCSC:P51654 GPC3
Reference Transcript
Other Identifiers
11729604_s_at
11752479_a_at
11754011_x_at
17114288
209220_PM_at
209220_at
2719
39350_at
4022458
4022459
4022460
4022461
4022462
4022463
4022479
4022499
4022506
4022508
4022517
4022518
4022567
4022568
4022583
4022584
8175234
A_33_P3230264
A_33_P3326634
GE58338
GO:0001658
GO:0001822
GO:0005515
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005794
GO:0005796
GO:0005886
GO:0007224
GO:0008285
GO:0009617
GO:0009653
GO:0009887
GO:0009948
GO:0009966
GO:0009986
GO:0010171
GO:0016020
GO:0016192
GO:0016477
GO:0023052
GO:0030154
GO:0030163
GO:0030282
GO:0030312
GO:0030316
GO:0030324
GO:0030414
GO:0030513
GO:0031012
GO:0035116
GO:0040008
GO:0042074
GO:0043202
GO:0043226
GO:0045732
GO:0045807
GO:0045879
GO:0045880
GO:0045926
GO:0046326
GO:0048856
GO:0048870
GO:0050673
GO:0050680
GO:0055085
GO:0060070
GO:0060071
GO:0060422
GO:0060828
GO:0060976
GO:0062023
GO:0072111
GO:0072138
GO:0072180
GO:0072203
GO:0090090
GO:0090263
GO:0098552
GO:0098772
GO:1905475
GO:2000050
GO:2000096
HMNXSV003050256
ILMN_2051972
L47125_s_at
PH_hs_0006599
TC0X001378.hg
Z37987_s_at
g1237180_3p_at
Participates
as a member of
Other forms of this molecule
GPC3(25-?) [lysosomal lumen]
HS(6)-GPC3 [lysosomal lumen]
HS(1)-GPC3 [Golgi lumen]
HS(2)-GPC3 [Golgi lumen]
HS(3)-GPC3 [Golgi lumen]
HS(4)-GPC3 [Golgi lumen]
HS(6)-GPC3 [Golgi lumen]
HS(5)-GPC3 [Golgi lumen]
Heparan-GPC3 [Golgi lumen]
Heparan(2)-GPC3 [Golgi lumen]
Heparan(4)-GPC3 [Golgi lumen]
Heparan(3)-GPC3 [Golgi lumen]
GPC3(25-?) [Golgi lumen]
XylS-GPC3(25-?) [Golgi lumen]
Gal-Xyl-GPC3 [Golgi lumen]
GlcA-Gal-Gal-Xyl-GPC3 [Golgi lumen]
Gal-Gal-Xyl-GPC3 [Golgi lumen]
p-GPC3 [endoplasmic reticulum lumen]
HS(4)-GPC3 [plasma membrane]
HS(6)-GPC3 [plasma membrane]
HS(2)-GPC3 [plasma membrane]
HS(1)-GPC3 [plasma membrane]
HS(3)-GPC3 [plasma membrane]
HS(5)-GPC3 [plasma membrane]
GPC3 [endoplasmic reticulum lumen]
Inferred To
GPC3 [Golgi lumen] (Bos taurus)
GPC3 [Golgi lumen] (Canis familiaris)
GPC3 [Golgi lumen] (Sus scrofa)
Gpc3 [Golgi lumen] (Mus musculus)
Gpc3 [Golgi lumen] (Rattus norvegicus)
gpc3 [Golgi lumen] (Danio rerio)
gpc3 [Golgi lumen] (Xenopus tropicalis)
Heparan(1)-GPC3 [Golgi lumen] (Gallus gallus)
dally [Golgi lumen] (Drosophila melanogaster)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63646) at unknown position
Modification
beta-D-GlcA-(1->4)-alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P32249 GPR183  1 0.527 3
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