GPR183 [plasma membrane]

Stable Identifier
R-HSA-8851676
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
G-protein coupled receptor 183, GP183_HUMAN
Locations in the PathwayBrowser
General
GPR183 (originally called EBI2) binds the oxysterol 7alpha,25-dihydroxycholesterol (7a,25-OHC) (Hannedouche et al. 2011, Liu et al. 2011). GPR183 is believed to played a key role in regulating B cell migration and responses (Gatto et al. 2009, Pereira et al. 2009, Yi et al. 2012, Sun & Liu 2015). It signals via Gi (Rosenkilde et al. 2006).
External Reference Information
External Reference
Gene Names
GPR183, EBI2
Chain
chain:1-361
Other Identifiers
11727428_at
11758555_s_at
16780592
1880
205419_PM_at
205419_at
3522663
3522664
3522665
3522669
7972557
931_at
A_23_P25566
GE57589
GO:0002250
GO:0002312
GO:0002313
GO:0002376
GO:0002407
GO:0004930
GO:0005886
GO:0006955
GO:0006959
GO:0007165
GO:0007186
GO:0008142
GO:0008289
GO:0010818
GO:0016020
GO:0023052
GO:0030154
GO:0030316
GO:0030595
GO:0030890
GO:0036145
GO:0048856
GO:0048870
GO:0060089
GO:0060326
GO:0061470
GO:0070374
GO:2000458
HMNXSV003030157
ILMN_1798706
ILMN_2168217
L08177_at
PH_hs_0000092
PH_hs_0040414
TC13000829.hg
g4826705_3p_at
g4826705_3p_x_at
Participates
Inferred To
Cross References
Guide to Pharmacology - Targets
81
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
Interactors (18)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P31431 SDC4  20 0.527 2
 UniProt:Q63HK5 TSH3      0.527 3
 UniProt:Q9HCG8 CWC22  1 0.527 2
 UniProt:P34741 SDC2  20 0.527 3
 UniProt:O14786 NRP1  1 0.527 3
 UniProt:Q8WVM7 STAG1  4 0.527 3
 UniProt:P35052 GPC1  20 0.527 4
 UniProt:Q13144 EIF2B5  1 0.527 4
 UniProt:Q14232 EIF2B1  1 0.527 4
 UniProt:Q8IYR6 TEFF1      0.527 2
 UniProt:Q9Y625 GPC6  20 0.527 3
 UniProt:Q9NR50 EIF2B3  1 0.527 4
 UniProt:P51654 GPC3  20 0.527 3
 UniProt:Q52LW3 ARHGAP29  1 0.527 2
 UniProt:O75487 GPC4  20 0.527 3
 UniProt:P49770 EIF2B2  1 0.527 4
 UniProt:Q6PL24 TMED8      0.527 2
 UniProt:Q53FV1 ORMDL2  1 0.527 2
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