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DST [plasma membrane]
Stable Identifier
R-HSA-447008
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
BP230 isoforms 1/2/3/4/5/8
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Type I hemidesmosome assembly (Homo sapiens)
BP230 interacts with keretin K5/K14 (Homo sapiens)
CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Homo sapiens)
BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
Type II hemidesmosome [plasma membrane] (Homo sapiens)
CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Homo sapiens)
BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
BP230 is recruited to the hemidesmosome (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
CD151 interacts with BP180 and the integrin alpha 6 subunit (Homo sapiens)
BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
CD151:BP230:BP180:Plectin:Integrin alpha 6 beta 4: Laminin [plasma membrane] (Homo sapiens)
BP230:BP180:Plectin:integrin alpha 6 beta 4:Laminin 332 [plasma membrane] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOU GTPase cycle (Homo sapiens)
RHOU binds effectors at the plasma membrane (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RHOU:GTP:RHOU effectors [plasma membrane] (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RHOV GTPase cycle (Homo sapiens)
RHOV binds effectors at the plasma membrane (Homo sapiens)
RHOV effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RHOV:GTP:RHOV effectors [plasma membrane] (Homo sapiens)
RHOV effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND1 GTPase cycle (Homo sapiens)
RND1 binds effectors (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND1:GTP:RND1 effectors [plasma membrane] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND2 GTPase cycle (Homo sapiens)
RND2 binds effectors (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND2:GTP:RND2 effectors [plasma membrane] (Homo sapiens)
RND2 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND3 GTPase cycle (Homo sapiens)
RND3 binds effectors (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
RND3:GTP:RND3 effectors [plasma membrane] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
DST [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03001 DST
Gene Names
DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728
Chain
chain:1-7570
Reference Genes
BioGPS Gene:667 DST
COSMIC (genes):DST DST
CTD Gene:667 DST
dbSNP Gene:667 DST
ENSEMBL:ENSG00000151914.22 DST
HGNC:1090 DST
KEGG Gene (Homo sapiens):667 DST
Monarch:667 DST
NCBI Gene:667 DST
OMIM:113810 DST
UCSC:Q03001 DST
Reference Transcript
RefSeq:NM_001723.5 DST
RefSeq:XM_017011224.1 DST
RefSeq:NM_001144770.1 DST
RefSeq:NM_183380.3 DST
RefSeq:NM_001144769.2 DST
RefSeq:NM_015548.4 DST
Other Identifiers
0002060022
0002060494
0002810433
0006520451
11727655_s_at
11737993_s_at
11740833_at
11740834_s_at
11743319_a_at
11743320_x_at
11745119_a_at
1553191_PM_at
1553191_at
17020317
204455_PM_at
204455_at
212253_PM_x_at
212253_x_at
212254_PM_s_at
212254_s_at
215016_PM_x_at
215016_x_at
216918_PM_s_at
216918_s_at
220154_PM_at
220154_at
2958326
2958327
2958328
2958329
2958330
2958332
2958335
2958336
2958337
2958342
2958345
2958350
2958352
2958353
2958355
2958356
2958358
2958360
2958361
2958363
2958365
2958368
2958370
2958371
2958372
2958373
2958374
2958375
2958377
2958378
2958379
2958380
2958382
2958383
2958385
2958386
2958387
2958388
2958389
2958390
2958392
2958395
2958396
2958397
2958398
2958399
2958400
2958401
2958402
2958403
2958404
2958405
2958407
2958423
2958424
2958425
2958426
2958427
2958428
2958430
2958432
2958434
2958435
2958436
2958437
2958440
2958445
2958446
2958447
2958448
2958449
2958451
2958452
2958453
2958454
2958455
2958456
2958457
2958458
2958459
2958460
2958461
2958462
2958463
2958464
2958465
2958466
2958467
2958468
2958469
2958470
2958471
2958473
2958474
2958475
2958476
2958477
2958478
2958479
2958480
2958482
2958486
2958487
2958488
2958489
2958490
2958491
2958493
2958494
2958496
2958497
2958498
2958500
2958501
2958502
2958505
2958506
2958507
2958508
2958509
2958510
2958511
2958512
2958513
2958514
2958515
2958516
2958517
2958519
2958520
2958527
2958538
2958541
2958542
2958547
2958563
2958564
32780_at
32781_f_at
32782_r_at
40304_at
55058_at
667
66826_at
8127234
A_23_P303718
A_23_P348159
A_23_P42530
A_23_P59388
A_33_P3339650
GE61369
GE81063
GO:0003779
GO:0005178
GO:0005198
GO:0005509
GO:0005515
GO:0005604
GO:0005622
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005856
GO:0005874
GO:0005882
GO:0005886
GO:0005925
GO:0005938
GO:0007010
GO:0007018
GO:0007155
GO:0007163
GO:0007229
GO:0008017
GO:0008022
GO:0008090
GO:0008092
GO:0009611
GO:0009925
GO:0015630
GO:0016020
GO:0016021
GO:0023052
GO:0030011
GO:0030018
GO:0030056
GO:0030312
GO:0030424
GO:0031012
GO:0031122
GO:0031252
GO:0031410
GO:0031581
GO:0031673
GO:0034330
GO:0035371
GO:0042060
GO:0042995
GO:0043226
GO:0045104
GO:0046872
GO:0048870
GO:0051010
GO:0070161
GO:0110165
GO:1904115
HMNXSV003002239
HMNXSV003037901
HMNXSV003047239
Hs.198689.0.S1_3p_a_at
Hs.198689.0.S2_3p_a_at
Hs.620.1.S1_3p_a_at
Hs2.198689.2.S1_3p_at
ILMN_1665873
ILMN_1666490
ILMN_1675992
ILMN_1703913
ILMN_2238302
ILMN_2287157
ILMN_2394276
M69225_at
PH_hs_0041091
TC06001828.hg
TC06003695.hg
g4502442_3p_at
Participates
as a candidate of
RND2 effectors [cytosol] (Homo sapiens)
RND3 effectors [cytosol] (Homo sapiens)
RHOV effectors [cytosol] (Homo sapiens)
RHOU effectors [cytosol] (Homo sapiens)
RND1 effectors [cytosol] (Homo sapiens)
BP230 [plasma membrane] (Homo sapiens)
Inferred To
shot [plasma membrane]
(Drosophila melanogaster)
dst [plasma membrane]
(Xenopus tropicalis)
Dst [plasma membrane]
(Rattus norvegicus)
DST [plasma membrane]
(Bos taurus)
DST [plasma membrane]
(Canis familiaris)
DST [plasma membrane]
(Danio rerio)
DST [plasma membrane]
(Gallus gallus)
DST [plasma membrane]
(Mus musculus)
DST [plasma membrane]
(Sus scrofa)
vab-10 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_899236.1
,
NP_001714.1
,
NP_056363.2
,
NP_001138241.1
,
NP_001138242.1
,
XP_016866713.1
OpenTargets
ENSG00000151914
GeneCards
Q03001
HPA
ENSG00000151914-DST
Ensembl
ENST00000370788
,
ENSP00000359824
,
ENSP00000359801
,
ENSG00000151914
,
ENST00000439203
,
ENST00000244364
,
ENSP00000404924
,
ENSP00000244364
,
ENST00000370765
PRO
Q03001
Pharos - Targets
Q03001
Orphanet
20829
PDB
3GJO
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NV70 EXOC1
2
EXOC1 [plasma membrane]
(R-HSA-2872284)
EXOC1 [cytosol]
(R-HSA-5623375)
0.553
2
UniProt:Q9UKG1 APPL1
1
APPL1 [endosome membrane]
(R-HSA-373630)
0.454
3
UniProt:Q96CV9 OPTN
5
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
0.454
2
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