Reactome | DST [plasma membrane]

DST [plasma membrane]

Stable Identifier

R-HSA-447008

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

BP230 isoforms 1/2/3/4/5/8

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q03001 DST

Gene Names

DST, BP230, BP240, BPAG1, DMH, DT, KIAA0728

Chain

chain:1-7570

Reference Genes

BioGPS Gene:667 DST

COSMIC (genes):DST DST

CTD Gene:667 DST

dbSNP Gene:667 DST

ENSEMBL:ENSG00000151914 DST

HGNC:1090 DST

KEGG:hsa:667 DST

Monarch:667 DST

NCBI Gene:667 DST

OMIM:113810 DST

UCSC:Q03001 DST

Reference Transcript

Participates

as a candidate of

Inferred To

shot [plasma membrane] (Drosophila melanogaster)

Dst [plasma membrane] (Mus musculus)

Dst [plasma membrane] (Rattus norvegicus)

DST [plasma membrane] (Bos taurus)

DST [plasma membrane] (Canis familiaris)

DST [plasma membrane] (Gallus gallus)

DST [plasma membrane] (Sus scrofa)

vab-10 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_899236.1, NP_001714.1, NP_056363.2, NP_001361659.1, XP_016866713.1, NP_001138242.1, NP_001138241.1

OpenTargets

ENSG00000151914

ENSEMBL

ENST00000370765, ENST00000370788, ENSP00000359824, ENSP00000359801, ENSP00000244364, ENST00000244364, ENST00000439203, ENSG00000151914, ENSP00000404924

HPA

ENSG00000151914-DST

GeneCards

DST

PRO

Q03001

Pharos - Targets

Q03001

Orphanet

DST

GlyGen

Q03001

PDB

3GJO, 7OLG

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NV70 EXOC1	2	EXOC1 [cytosol] (R-HSA-5623375) EXOC1 [plasma membrane] (R-HSA-2872284)	0.553	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.483	13
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.454	3
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) OPTN [Golgi membrane] (R-HSA-2161111) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.454	2

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