Reactome | BBS7 [cytosol]

BBS7 [cytosol]

Stable Identifier

R-HSA-5617632

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

BBS2L1

GO Cellular Component

ciliary basal body (0036064)

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8IWZ6 BBS7

Gene Names

BBS7, BBS2L1

Chain

chain:1-715

Reference Genes

BioGPS Gene:55212 Q8IWZ62

COSMIC (genes):BBS7 BBS7

CTD Gene:55212 Q8IWZ62

dbSNP Gene:55212 Q8IWZ62

ENSEMBL:ENSG00000138686 BBS7

HGNC:18758 Q8IWZ62

KEGG:hsa:55212 Q8IWZ62

Monarch:55212 Q8IWZ62

NCBI Gene:55212 Q8IWZ62

OMIM:607590 Q8IWZ62

UCSC:Q8IWZ6 Q8IWZ62

Reference Transcript

Participates

as an input of

Formation of the BBSome (Homo sapiens)

as a component of

BBSome [cytosol] (Homo sapiens)

Inferred To

osm-12 [cytosol] (Caenorhabditis elegans)

BBS7 [cytosol] (Bos taurus)

BBS7 [cytosol] (Canis familiaris)

BBS7 [cytosol] (Gallus gallus)

BBS7 [cytosol] (Sus scrofa)

bbs7 [cytosol] (Xenopus tropicalis)

Bbs7 [cytosol] (Mus musculus)

Bbs7 [cytosol] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000138686

ENSEMBL

ENSG00000138686, ENST00000506636, ENSP00000264499, ENST00000264499, ENSP00000423626

HPA

ENSG00000138686-BBS7

GeneCards

BBS7

PRO

Q8IWZ6

Pharos - Targets

Q8IWZ6

Orphanet

BBS7

Interactors (32)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BXC9 BBS2	1	BBS2 [cytosol] (R-HSA-5617637)	0.918	17
UniProt:Q8NFJ9 BBS1	1	BBS1 [cytosol] (R-HSA-5617640)	0.883	11
UniProt:Q96RK4 BBS4	1	BBS4 [cytosol] (R-HSA-5617635)	0.879	8
UniProt:Q3SYG4 BBS9	1	BBS9 [cytosol] (R-HSA-5617630)	0.814	9
UniProt:Q8N3I7 BBS5	1	BBS5 [cytosol] (R-HSA-5617633)	0.789	9
UniProt:Q9NQ48 LZTFL1	1	LZTFL1 [cytosol] (R-HSA-5617789)	0.789	6
UniProt:Q6ZW61 BBS12	1	BBS12 [cytosol] (R-HSA-5624082)	0.784	8
UniProt:Q8TAM1 BBS10	1	BBS10 [cytosol] (R-HSA-5624080)	0.748	5
UniProt:Q8TAM2 TTC8	1	TTC8 [cytosol] (R-HSA-5617600)	0.725	5
UniProt:Q9NPJ1 MKKS	1	MKKS [cytosol] (R-HSA-5624086)	0.662	7
UniProt:P78371 CCT2	3	CCT2 [azurophil granule lumen] (R-HSA-6799356) CCT2 [extracellular region] (R-HSA-6806220) CCT2 [cytosol] (R-HSA-390464)	0.597	3
UniProt:P05062 ALDOB	3	ALDOB A174D [cytosol] (R-HSA-5656456) ALDOB A149P [cytosol] (R-HSA-5656457) ALDOB [cytosol] (R-HSA-70339)	0.543	4
UniProt:Q9NXC5 MIOS	1	MIOS [lysosomal membrane] (R-HSA-9638223)	0.527	2
UniProt:Q8TAM2-4 TTC8			0.527	2
UniProt:Q15269 PWP2	1	PWP2 [nucleoplasm] (R-HSA-6790680)	0.527	2
UniProt:Q6P9H4 CNKR3			0.527	2
UniProt:Q9Y4P8 WIPI2	1	WIPI2 [cytosol] (R-HSA-5678305)	0.527	2
UniProt:O76038 SEGN			0.527	3
UniProt:Q6AHZ1 Z518A			0.527	2
UniProt:Q96MH7 CE034			0.527	2
UniProt:Q13232 NME3	1	NME3 [cytosol] (R-HSA-6806883)	0.527	2
UniProt:P54277 PMS1			0.527	2
UniProt:Q8NDZ2 SIMC1			0.527	2
UniProt:Q9H792 PEAK1	1	PEAK1 [cytosol] (R-HSA-9715162)	0.527	2
UniProt:P16402 H1-3	1	HIST1H1D [nucleoplasm] (R-HSA-211241)	0.527	2
UniProt:Q6PCD5 RFWD3			0.527	2
UniProt:Q9H992 MARH7			0.527	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.524	3
UniProt:Q15051 IQCB1	1	IQCB1 [cytosol] (R-HSA-5626648)	0.518	5
UniProt:Q8NDW8 TT21A			0.508	2
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.462	2
UniProt:P49368 CCT3	1	CCT3 [cytosol] (R-HSA-390463)	0.462	2

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