Reactome | NDUFS1 [mitochondrial matrix]

NDUFS1 [mitochondrial matrix]

Stable Identifier

R-HSA-6788513

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

NADH-ubiquinone oxidoreductase 75 kDa subunit

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P28331 NDUFS1

Gene Names

NDUFS1

Chain

transit peptide:1-23, chain:24-727

Reference Genes

COSMIC (genes):NDUFS1 NDUFS1

dbSNP Gene:4719 NDUFS1

ENSEMBL:ENSG00000023228 NDUFS1

Participates

as a member of

as a component of

NDUFS1:2x4Fe-4S [mitochondrial matrix] (Homo sapiens)

Inferred To

NDUFS1 [mitochondrial matrix] (Bos taurus)

NDUFS1 [mitochondrial matrix] (Canis familiaris)

NDUFS1 [mitochondrial matrix] (Dictyostelium discoideum)

NDUFS1 [mitochondrial matrix] (Drosophila melanogaster)

NDUFS1 [mitochondrial matrix] (Gallus gallus)

NDUFS1 [mitochondrial matrix] (Mus musculus)

NDUFS1 [mitochondrial matrix] (Rattus norvegicus)

NDUFS1 [mitochondrial matrix] (Sus scrofa)

Ghost homologue of NDUFS1 [mitochondrial matrix] (Caenorhabditis elegans)

Ghost homologue of NDUFS1 [mitochondrial matrix] (Danio rerio)

Ghost homologue of NDUFS1 [mitochondrial matrix] (Xenopus tropicalis)

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.725	7
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.643	5
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.527	2
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.527	2
UniProt:Q99650 OSMR	1	OSMR [plasma membrane] (R-HSA-448654)	0.499	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7
UniProt:Q8IWL3 HSCB	5	HSCB [mitochondrial matrix] (R-HSA-1299438) HSCB(1-30) [mitochondrial matrix] (R-HSA-8986120) HSCB(1-235) [mitochondrial inner membrane] (R-HSA-1299443) HSCB [mitochondrial inner membrane] (R-HSA-1299447) HSCB(1-235) [mitochondrial intermembrane space] (R-HSA-1299456)	0.462	6

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