Reactome | IMP3 [nucleoplasm]

IMP3 [nucleoplasm]

Stable Identifier

R-HSA-6790664

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U3 small nucleolar ribonucleoprotein protein IMP3, IMP3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NV31 IMP3

Gene Names

IMP3, C15orf12, MRPS4

Chain

chain:1-184

Reference Genes

BioGPS Gene:55272 IMP3

COSMIC (genes):IMP3 IMP3

CTD Gene:55272 IMP3

dbSNP Gene:55272 IMP3

ENSEMBL:ENSG00000177971 IMP3

ENSEMBL_homo_sapiens_GENE:ENSG00000177971.9 IMP3

HGNC:14497 IMP3

KEGG Gene (Homo sapiens):55272 IMP3

Monarch:55272 IMP3

NCBI Gene:55272 IMP3

OMIM:612980 IMP3

UCSC:Q9NV31 IMP3

Reference Transcript

RefSeq:NM_018285.3 IMP3

Other Identifiers

11715773_a_at

11715774_s_at

16811847

221688_PM_s_at

221688_s_at

3633552

3633553

3633554

3633555

3633556

3633557

3633560

3633561

3633562

55272

57201_at

7990540

A_23_P33809

GE55927

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005840

GO:0006364

GO:0015935

GO:0019843

GO:0030490

GO:0030515

GO:0030684

GO:0032040

GO:0034457

GO:0042254

GO:0042274

GO:0043226

GO:1990904

HMNXSV003037277

ILMN_1733696

PH_hs_0026912

PH_hs_0030727

TC15001669.hg

g12053320_3p_s_at

Participates

as a component of

MPP10 complex [nucleoplasm] (Homo sapiens)

Inferred To

Imp3 [nucleoplasm] (Mus musculus)

mRpS4 [nucleoplasm] (Drosophila melanogaster)

IMP3 [nucleoplasm] (Caenorhabditis elegans)

IMP3 [nucleoplasm] (Canis familiaris)

IMP3 [nucleoplasm] (Gallus gallus)

IMP3 [nucleoplasm] (Plasmodium falciparum)

IMP3 [nucleoplasm] (Saccharomyces cerevisiae)

IMP3 [nucleoplasm] (Sus scrofa)

imp3 [nucleoplasm] (Dictyostelium discoideum)

imp3 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of IMP3 [nucleoplasm] (Bos taurus)

Ghost homologue of IMP3 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_060755.1

OpenTargets

ENSG00000177971

GeneCards

Q9NV31

HPA

ENSG00000177971-IMP3

Ensembl

ENSP00000326981, ENSG00000177971, ENSP00000385217, ENST00000314852, ENST00000403490

PRO

Q9NV31

Pharos - Targets

Q9NV31

PDB

7MQ9, 7MQA, 2CQJ, 7MQ8

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.666	4
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) N [plasma membrane] (R-COV-9694356) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [cytosol] (R-COV-9694300) p-S188,206-N [cytosol] (R-COV-9729324) p-8S-N [cytosol] (R-COV-9729335) p-8S,2T-N [cytosol] (R-COV-9729277) p-11S,2T-N [cytosol] (R-COV-9729264) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:P62753 RPS6	4	RPS6 [nucleoplasm] (R-HSA-6790606) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [cytosol] (R-HSA-72381)	0.483	2