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COPG2 [cytosol]
Stable Identifier
R-HSA-6807747
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
Active ARF recruits coatomer (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
Active ARF recruits coatomer (Homo sapiens)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
COPI vesicle uncoating (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
Active ARF recruits coatomer to the Golgi (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
COPI vesicle uncoating at the ER (Homo sapiens)
coatomer [cytosol] (Homo sapiens)
tetrameric coatomer complex [cytosol] (Homo sapiens)
COPG1,2 [cytosol] (Homo sapiens)
COPG2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UBF2 COPG2
Gene Names
COPG2
Chain
chain:1-871
Reference Genes
BioGPS Gene:26958 COPG2
COSMIC (genes):COPG2 COPG2
CTD Gene:26958 COPG2
dbSNP Gene:26958 COPG2
ENSEMBL:ENSG00000158623 COPG2
HGNC:2237 COPG2
KEGG:hsa:26958 COPG2
Monarch:26958 COPG2
NCBI Gene:26958 COPG2
OMIM:604355 COPG2
UCSC:Q9UBF2 COPG2
Reference Transcript
RefSeq:NM_001290033.1 COPG2
RefSeq:NM_012133.5 COPG2
Other Identifiers
11728705_at
11747220_a_at
17062906
223457_PM_at
223457_at
233569_PM_at
233569_at
26958
3072631
3072632
3072633
3072634
3072635
3072637
3072639
3072641
3072650
3072651
3072652
3072653
3072668
3072669
3072670
3072671
3072675
3072676
77933_at
8142945
A_23_P61280
GE80515
GO:0000139
GO:0005198
GO:0005737
GO:0005783
GO:0005789
GO:0005793
GO:0005794
GO:0005829
GO:0006886
GO:0006888
GO:0006890
GO:0006891
GO:0007018
GO:0009306
GO:0015031
GO:0016020
GO:0016192
GO:0030117
GO:0030126
GO:0030133
GO:0030137
GO:0030426
GO:0030663
GO:0031090
GO:0031410
GO:0043226
GO:0072384
HMNXSV003012213
HMNXSV003019568
Hs.6421.1.A1_3p_at
Hs2.145223.1.S1_3p_s_at
ILMN_1809496
PH_hs_0013578
TC07003379.hg
g11094284_3p_at
Participates
as a member of
COPG1,2 [cytosol] (Homo sapiens)
Other forms of this molecule
COPG2 [endoplasmic reticulum membrane]
COPG2 [Golgi membrane]
COPG2 [transport vesicle]
Inferred To
copg2 [cytosol]
(Danio rerio)
copg2 [cytosol]
(Xenopus tropicalis)
Copg2 [cytosol]
(Mus musculus)
Copg2 [cytosol]
(Rattus norvegicus)
SEC21 [cytosol]
(Saccharomyces cerevisiae)
COPG2 [cytosol]
(Bos taurus)
COPG2 [cytosol]
(Canis familiaris)
COPG2 [cytosol]
(Gallus gallus)
COPG2 [cytosol]
(Plasmodium falciparum)
COPG2 [cytosol]
(Sus scrofa)
gammaCOP [cytosol]
(Drosophila melanogaster)
copg-1 [cytosol]
(Caenorhabditis elegans)
sec21 [cytosol]
(Schizosaccharomyces pombe)
copG [cytosol]
(Dictyostelium discoideum)
Cross References
ENSEMBL
ENST00000330992
,
ENSG00000158623
,
ENSP00000402346
,
ENST00000425248
,
ENSP00000331218
OpenTargets
ENSG00000158623
GeneCards
COPG2
HPA
ENSG00000158623-COPG2
PRO
Q9UBF2
Pharos - Targets
Q9UBF2
GlyGen
Q9UBF2
HMDB Protein
HMDBP08334
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.569
3
UniProt:P04233 CD74
13
CD74 [plasma membrane]
(R-HSA-2130666)
CD74 [lysosomal membrane]
(R-HSA-2130320)
CD74(1-176) [lysosomal membrane]
(R-HSA-2130602)
CD74 [endocytic vesicle membrane]
(R-HSA-2130460)
CD74 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130522)
CD74 [transport vesicle membrane]
(R-HSA-2130624)
CD74 [trans-Golgi network membrane]
(R-HSA-2130493)
CD74 [Golgi membrane]
(R-HSA-2214388)
CD74 [ER to Golgi transport vesicle membrane]
(R-HSA-2130456)
CD74 [lumenal side of endoplasmic reticulum membrane]
(R-HSA-1181241)
CD74(1-117) [lysosomal membrane]
(R-HSA-2130632)
CD74(81-104) [lysosomal membrane]
(R-HSA-2130446)
CD74(81-104) [lysosomal lumen]
(R-HSA-2213220)
0.527
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.527
3
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
7
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