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DSG1 [cornified envelope]
Stable Identifier
R-HSA-8847719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cornified envelope
Synonyms
Desmoglein 1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
Desmosome [cornified envelope] (Homo sapiens)
Desmogelins [cornified envelope] (Homo sapiens)
DSG1 [cornified envelope] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02413 DSG1
Gene Names
DSG1, CDHF4
Chain
signal peptide:1-23, propeptide:24-49, chain:50-1049
Reference Genes
BioGPS Gene:1828 DSG1
COSMIC (genes):DSG1 DSG1
CTD Gene:1828 DSG1
dbSNP Gene:1828 DSG1
ENSEMBL:ENSG00000134760 DSG1
ENSEMBL_homo_sapiens_GENE:ENSG00000134760.6 DSG1
HGNC:3048 DSG1
KEGG Gene (Homo sapiens):1828 DSG1
Monarch:1828 DSG1
NCBI Gene:1828 DSG1
OMIM:125670 DSG1
UCSC:Q02413 DSG1
Reference Transcript
RefSeq:NM_001942.3 DSG1
Other Identifiers
11739886_at
11739887_at
11747872_a_at
16851708
1828
206642_PM_at
206642_at
3783401
3783402
3783403
3783404
3783405
3783406
3783407
3783408
3783410
3783412
3783413
3783414
3783415
3783416
3783417
3783418
3783420
3783421
3783422
3783423
3783424
3783425
3783426
3783427
3783428
3783429
3783430
3783432
3783434
39586_at
8020724
A_14_P119744
A_33_P3265189
GE79749
GO:0001533
GO:0005509
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005911
GO:0007043
GO:0007155
GO:0007156
GO:0009898
GO:0015643
GO:0016020
GO:0016324
GO:0016328
GO:0016339
GO:0022414
GO:0030057
GO:0031410
GO:0032570
GO:0034330
GO:0043226
GO:0045295
GO:0046872
GO:0050821
GO:0060135
GO:0070161
GO:0098609
GO:0101003
HMNXSV003019326
ILMN_1794662
ILMN_1830761
PH_hs_0000347
TC18000124.hg
X56654_at
g4503400_3p_at
Participates
as a member of
Desmogelins [cornified envelope] (Homo sapiens)
Other forms of this molecule
DSG1 [ficolin-1-rich granule membrane]
DSG1(889-1049) [cytosol]
DSG1(50-888) [plasma membrane]
DSG1 [plasma membrane]
Inferred To
Dsg1a [cornified envelope]
(Mus musculus)
Dsg1 [cornified envelope]
(Rattus norvegicus)
DSG1 [cornified envelope]
(Bos taurus)
DSG1 [cornified envelope]
(Canis familiaris)
DSG1 [cornified envelope]
(Sus scrofa)
Homologues of DSG1 [cornified envelope]
(Sus scrofa)
Cross References
RefSeq
NP_001933.2
OpenTargets
ENSG00000134760
GeneCards
Q02413
HPA
ENSG00000134760-DSG1
Ensembl
ENST00000257192
,
ENSP00000257192
,
ENSG00000134760
PRO
Q02413
Pharos - Targets
Q02413
Orphanet
15893
HMDB Protein
HMDBP07658
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NU19 TB22B
0.527
2
UniProt:Q96ER9 MITOK
0.527
2
UniProt:P57076 CF298
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
5
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