PTK6 binds AKT1

Stable Identifier
R-HSA-8848751
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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PTK6 binds AKT1
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PTK6 binds AKT1 and this interaction involves the SH3 domain of PTK6 and the proline rich sequence in the C-terminus of AKT1 (Zheng et al. 2010).

Literature References
PubMed ID Title Journal Year
20606012 Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor

Zheng, Y, Wang, Z, Peng, M, Tyner, AL, Asara, JM

Mol. Cell. Biol. 2010
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Orthologous Events
PTK6 binds AKT1 (Caenorhabditis elegans)
PTK6 binds AKT1 (Danio rerio)
PTK6 binds AKT1 (Mus musculus)
PTK6 binds AKT1 (Rattus norvegicus)
Authored
Orlic-Milacic, M  (2016-01-05)
Reviewed
Pires, IM  (2016-02-07)
Created
Orlic-Milacic, M  (2015-12-10)
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