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SCP2 [cytosol]
Stable Identifier
R-HSA-9033130
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Non-specific lipid-transfer protein, NLTP_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
SCP2 [cytosol] (Homo sapiens)
PEX5S,L binds cargo proteins containing PTS1 (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
SCP2 [cytosol] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
SCP2 [cytosol] (Homo sapiens)
PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
SCP2 [cytosol] (Homo sapiens)
PEX5S,L:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)
PEX5S,L:Cargo protein [cytosol] (Homo sapiens)
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
SCP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22307 SCP2
Gene Names
SCP2
Chain
chain:1-547
Reference Genes
BioGPS Gene:6342 P223073
COSMIC (genes):SCP2 CTDSP2
CTD Gene:6342 P223073
dbSNP Gene:6342 P223073
ENSEMBL:ENSG00000116171 SCP2
HGNC:10606 P223073
KEGG:hsa:6342 P223073
Monarch:6342 P223073
NCBI Gene:6342 P223073
OMIM:184755 P223073
UCSC:P22307 P223073
Reference Transcript
RefSeq:NM_001007250.2 P223073
RefSeq:NM_001193599.1 P223073
RefSeq:NM_001007100.2 P223073
RefSeq:NM_001007098.2 P223073
RefSeq:NM_002979.4 P223073
RefSeq:NM_001007099.2 P223073
RefSeq:NM_001193617.1 P223073
RefSeq:XM_017002046.1 P223073
Participates
as a member of
Cargo proteins containing PTS1 [cytosol] (Homo sapiens)
Other forms of this molecule
SCP2 [peroxisomal matrix]
SCP2(1-424) [peroxisomal matrix]
SCP2(425-547) [peroxisomal matrix]
Inferred To
ScpX [cytosol]
(Drosophila melanogaster)
SCP2 [cytosol]
(Bos taurus)
SCP2 [cytosol]
(Canis familiaris)
SCP2 [cytosol]
(Gallus gallus)
Scp2 [cytosol]
(Mus musculus)
Scp2 [cytosol]
(Rattus norvegicus)
Cross References
OpenTargets
ENSG00000116171
ENSEMBL
ENST00000371514
,
ENST00000371513
,
ENST00000430330
,
ENSP00000406636
,
ENSP00000386214
,
ENST00000435345
,
ENST00000528311
,
ENSP00000360568
,
ENSP00000434132
,
ENSP00000384569
,
ENSP00000360564
,
ENSP00000396413
,
ENSP00000435783
,
ENST00000371509
,
ENSG00000116171
,
ENST00000408941
,
ENST00000488965
,
ENST00000407246
,
ENSP00000360569
ZINC - Substances
NLTP_HUMAN
ZINC target
P22307
PRO
P22307
PDB
2C0L
,
1QND
IntEnz
2.3.1.176
,
2.3.1.16
HPA
ENSG00000116171-SCP2
GeneCards
SCP2
Pharos - Targets
P22307
Orphanet
SCP2
ZINC - Predictions - Purchasable
NLTP_HUMAN
HMDB Protein
HMDBP00440
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15645 PCH2
0.666
4
UniProt:P49817 Cav1
6
caveolin-1 [lipid droplet]
(R-MMU-163603)
Cav1 [endocytic vesicle membrane]
(R-MMU-535009)
Cav1 [lipid droplet]
(R-MMU-163510)
Cav1 [early endosome membrane]
(R-MMU-5368451)
Cav1 [plasma membrane]
(R-MMU-534994)
Cav1 [Golgi membrane]
(R-MMU-204504)
0.463
3
UniProt:Q03135 CAV1
5
CAV1 [Golgi membrane]
(R-HSA-204504)
CAV1 [plasma membrane]
(R-HSA-534994)
CAV1 [early endosome membrane]
(R-HSA-5368451)
CAV1 [lipid droplet]
(R-HSA-163510)
CAV1 [endocytic vesicle membrane]
(R-HSA-535009)
0.454
3
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