Reactome | phospho-p-Y419-SRC [cytosol]

phospho-p-Y419-SRC [cytosol]

Stable Identifier

R-GGA-8964276

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

P00523

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P00523 SRC

Gene Names

SRC

Chain

initiator methionine:, chain:2-533

Reference Genes

BioGPS Gene:396442 SRC

KEGG:gga:396442 SRC

Monarch:396442 SRC

NCBI Gene:396442 SRC

UCSC:P00523 SRC

Reference Transcript

Participates

as an output of

G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Gallus gallus)

as a component of

G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] (Gallus gallus)

Other forms of this molecule

SRC-2 [cytosol]

phospho-MyrG-p-Y419-SRC [plasma membrane]

SRC-1 [plasma membrane]

phospho-MyrG,p-Y530-SRC [plasma membrane]

phospho-p-Y419-SRC [cytosol]

MyrG-SRC [plasma membrane]

Src [cytosol]

SRC [cytosol]

Inferred From

p-Y419-SRC [cytosol] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 420 (in Homo sapiens)

Coordinate

420

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_015151834.1, NP_990788.2

ZINC - Investigational

SRC_CHICK

ZINC - World Drugs

SRC_CHICK

ZINC - FDA approved

SRC_CHICK

ZINC - Substances

SRC_CHICK

ZINC target

P00523

PRO

P00523

ZINC - Predictions - Purchasable

SRC_CHICK

PDB

4HVV, 1P13, 2QLQ, 7A3A, 7A36, 4JZ4, 4RTY, 3EL8, 3OF0, 3F3T, 3FJ5, 7A37, 4AGW, 6HVE, 3D7U, 2HWO, 1PRL, 5D11, 3LOK, 6XVO, 1RLQ, 3EN4, 5XP5, 7NES, 3U51, 3QLG, 5K9I, 6L8L, 2OIQ, 4OMM, 7A31, 7PW0, 7PVY, 3DQX, 1F2F, 2QQ7, 4OMQ, 7D57, 7A35, 7A34, 7A39, 3OEZ, 7AH3, 5TEH, 3TZ7, 4FIC, 4YBK, 6XX2, 7A3D, 6HVF, 3F3U, 4JZ3, 2QI8, 6XVN, 4U5J, 5SWH, 1RLP, 5T0P, 3EN5, 5XP7, 3QLF, 5OB1, 4RTU, 4LGH, 5OAV, 3G6H, 4QT7, 5SYS, 4OMN, 7PVZ, 3GEQ, 7A30, 5I11, 4RTW, 7A33, 4HVW, 4YBJ, 5J5S, 4O2P, 3TZ8, 4LE9, 7A3C, 4RTZ, 6WIW, 2HWP, 5EC7, 3F3V, 6XX5, 3UQG, 5D10, 1NLP, 3UQF, 3F6X, 3EN6, 7NET, 3TZ9, 5OB0, 4LGG, 3SVV, 7PVX, 4OMO, 2PTK, 1SRM, 4RTV, 7A3B, 4HVU, 4OMP, 3G5D, 4MCV, 3EL7, 7A3E, 3DQW, 4RTX, 7WF5, 7A38, 6XX3, 3D7T, 6XX4, 3U4W, 3F3W, 5D12, 1F1W, 1PRM, 5BMM, 5ECA, 6XVM, 1NLO, 3EN7, 7NER, 4DGG, 7D5O, 5OB2, 7PVW, 7A32, 4OML, 3G6G, 1SRL

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P41240 CSK	2	CSK [cytosol] (R-HSA-203776) CSK [plasma membrane] (R-HSA-180499)	0.719	7
UniProt:P18433 PTPRA	1	PTPRA [plasma membrane] (R-HSA-388755)	0.59	4
UniProt:Q00944	11	phospho-p-6Y-PTK2 [cytosol] (R-GGA-354128) phospho-p-Y397-PTK2 [cytosol] (R-GGA-354068) PTK2 [cytosol] (R-GGA-201621) PTK2(1-772) [cytosol] (R-GGA-202827) PTK2(773-1052) [cytosol] (R-GGA-202829) phospho-p-5Y-PTK2 [cytosol] (R-GGA-5218711) phospho-p-5Y,S732-PTK2 [cytosol] (R-GGA-5229006) phospho-p-6Y,S732-PTK2 [cytosol] (R-GGA-5218694) phospho-pY-PTK2 [cytosol] (R-GGA-9632393) phospho-p-Y194,Y397-PTK2 [cytosol] (R-GGA-8874600) phospho-p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-GGA-8874613)	0.589	3
UniProt:Q9QWY8-1 ASAP1			0.581	3
UniProt:O88703	1	HCN2 [plasma membrane] (R-MMU-977502)	0.581	5
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.564	2
UniProt:Q90738 AFAP1			0.564	3
UniProt:Q9Y4D1 DAAM1	1	DAAM1 [cytosol] (R-HSA-351052)	0.556	3
UniProt:Q9QWY8-2 ASAP1			0.544	2
UniProt:P61980	2	Hnrnpk [nucleoplasm] (R-RNO-4570532) Hnrnpk [nucleoplasm] (R-RNO-71945)	0.544	2
UniProt:P18052	1	PTPRA [plasma membrane] (R-MMU-388755)	0.525	2

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