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SREBF1(1-1147) [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-1368141
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
SREBF1, Sterol regulatory element-binding protein 1, SRBP1_HUMAN, SREBP1
Locations in the PathwayBrowser
Expand all
Circadian Clock (Homo sapiens)
RORA activates gene expression (Homo sapiens)
Expression of SREBF1 (SREBP1) (Homo sapiens)
SREBF1(1-1147) [endoplasmic reticulum membrane] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
FOXO-mediated transcription (Homo sapiens)
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes (Homo sapiens)
SREBF1 gene expression is inhibited by FOXO1 (Homo sapiens)
SREBF1(1-1147) [endoplasmic reticulum membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Cholesterol biosynthesis (Homo sapiens)
DHCR24 reduces LAN to 24,25-dhLAN (Homo sapiens)
SREBP1,2 [endoplasmic reticulum membrane] (Homo sapiens)
SREBF1(1-1147) [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P36956 SREBF1
Gene Names
SREBF1, BHLHD1, SREBP1
Chain
chain:1-1147, chain:1-490
Reference Genes
COSMIC (genes):SREBF1 SREBF1
dbSNP Gene:6720 SREBF1
ENSEMBL:ENSG00000072310 SREBF1
Participates
as an output of
Expression of SREBF1 (SREBP1) (Homo sapiens)
SREBF1 gene expression is inhibited by FOXO1 (Homo sapiens)
as a member of
SREBP1,2 [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
sbp-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
SREBF1(1-1147) [endoplasmic reticulum membrane]
(Gallus gallus)
SREBF1 [endoplasmic reticulum membrane]
(Bos taurus)
SREBF1 [endoplasmic reticulum membrane]
(Canis familiaris)
SREBF1 [endoplasmic reticulum membrane]
(Sus scrofa)
Srebf1 [endoplasmic reticulum membrane]
(Mus musculus)
Srebf1 [endoplasmic reticulum membrane]
(Rattus norvegicus)
srebf1 [endoplasmic reticulum membrane]
(Danio rerio)
srebf1 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54253 ATX1
0.666
5
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
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