Reactome | HLA-H [recycling endosome membrane]

HLA-H [recycling endosome membrane]

Stable Identifier

R-HSA-8863855

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

recycling endosome membrane

Synonyms

Putative HLA class I histocompatibility antigen, alpha chain H, HLAH_HUMAN

Locations in the PathwayBrowser

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Immune System (Homo sapiens)

- Adaptive Immune System (Homo sapiens)
  - Class I MHC mediated antigen processing & presentation (Homo sapiens)
    - Antigen processing-Cross presentation (Homo sapiens)
      - ER-Phagosome pathway (Homo sapiens)
        
        Fusion of ERC and phagosome (Homo sapiens)
        
        Class I MHC HC:B2M:Erp57 [recycling endosome membrane] (Homo sapiens)
        
        Class I MHC heavy chain (MHC HC) [recycling endosome membrane] (Homo sapiens)
        
        HLA-H [recycling endosome membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P01893 HLA-H

Gene Names

HLA-H, HLAH

Chain

signal peptide:1-24, chain:25-362

Reference Genes

HGNC:4965 HLA-H

OMIM:142800 HLA-H

UCSC:P01893 HLA-H

Participates

as a member of

Class I MHC heavy chain (MHC HC) [recycling endosome membrane] (Homo sapiens)

Other forms of this molecule

HLA-H [phagocytic vesicle membrane]

HLA-H [early endosome membrane]

HLA-H [ER to Golgi transport vesicle membrane]

HLA-H [Golgi membrane]

HLA-H [plasma membrane]

HLA-H [azurophil granule membrane]

HLA-H [lumenal side of endoplasmic reticulum membrane]

Inferred To

RT1-M1-5 [recycling endosome membrane] (Rattus norvegicus)

RT1-M2 [recycling endosome membrane] (Rattus norvegicus)

mhc1zfa [recycling endosome membrane] (Danio rerio)

RT1-M1-2 [recycling endosome membrane] (Rattus norvegicus)

BF1 [recycling endosome membrane] (Gallus gallus)

H2-T3 [recycling endosome membrane] (Mus musculus)

H2-D1 [recycling endosome membrane] (Mus musculus)

mhc1zca [recycling endosome membrane] (Danio rerio)

H2-M2 [recycling endosome membrane] (Mus musculus)

H2-M10.1 [recycling endosome membrane] (Mus musculus)

RT1-M3-1 [recycling endosome membrane] (Rattus norvegicus)

H2-Q10 [recycling endosome membrane] (Mus musculus)

H2-M10.4 [recycling endosome membrane] (Mus musculus)

H2-M5 [recycling endosome membrane] (Mus musculus)

Homologues of class I MHC B7 [recycling endosome membrane] (Bos taurus)

Homologues of class I MHC B7 [recycling endosome membrane] (Canis familiaris)

Homologues of class I MHC B7 [recycling endosome membrane] (Danio rerio)

Homologues of class I MHC B7 [recycling endosome membrane] (Gallus gallus)

Homologues of class I MHC B7 [recycling endosome membrane] (Mus musculus)

Homologues of class I MHC B7 [recycling endosome membrane] (Rattus norvegicus)

Homologues of class I MHC B7 [recycling endosome membrane] (Sus scrofa)

mhc1uba [recycling endosome membrane] (Danio rerio)

RT1-M10-1 [recycling endosome membrane] (Rattus norvegicus)

H2-T23 [recycling endosome membrane] (Mus musculus)

RT1-O1l1 [recycling endosome membrane] (Rattus norvegicus)

H2-Q7 [recycling endosome membrane] (Mus musculus)

RT1-CE2 [recycling endosome membrane] (Rattus norvegicus)

H2-Q4 [recycling endosome membrane] (Mus musculus)

H2-Q1 [recycling endosome membrane] (Mus musculus)

H2-M10.5 [recycling endosome membrane] (Mus musculus)

RT1-S3 [recycling endosome membrane] (Rattus norvegicus)

H2-M10.6l [recycling endosome membrane] (Rattus norvegicus)

LOC100513601 [recycling endosome membrane] (Sus scrofa)

ENSRNOG00000069480 [recycling endosome membrane] (Rattus norvegicus)

mhc1uma [recycling endosome membrane] (Danio rerio)

BFIV21 [recycling endosome membrane] (Gallus gallus)

SLA-3 [recycling endosome membrane] (Sus scrofa)

H2-M9 [recycling endosome membrane] (Mus musculus)

RT1-M5 [recycling endosome membrane] (Rattus norvegicus)

SLA-6 [recycling endosome membrane] (Sus scrofa)

DLA88 [recycling endosome membrane] (Canis familiaris)

mhc1zba [recycling endosome membrane] (Danio rerio)

class I MHC B7 [recycling endosome membrane] (Bos taurus)

class I MHC B7 [recycling endosome membrane] (Canis familiaris)

class I MHC B7 [recycling endosome membrane] (Gallus gallus)

class I MHC B7 [recycling endosome membrane] (Mus musculus)

class I MHC B7 [recycling endosome membrane] (Sus scrofa)

RT1-CE10 [recycling endosome membrane] (Rattus norvegicus)

H2-M3 [recycling endosome membrane] (Mus musculus)

AABR07044308.2 [recycling endosome membrane] (Rattus norvegicus)

H2-K1 [recycling endosome membrane] (Mus musculus)

H2-M10.2 [recycling endosome membrane] (Mus musculus)

H2-T22 [recycling endosome membrane] (Mus musculus)

RT1-M1-4 [recycling endosome membrane] (Rattus norvegicus)

SLA-8 [recycling endosome membrane] (Sus scrofa)

H2-Q2 [recycling endosome membrane] (Mus musculus)

RT1-CE14 [recycling endosome membrane] (Rattus norvegicus)

SLA-2 [recycling endosome membrane] (Sus scrofa)

H2-M10.3 [recycling endosome membrane] (Mus musculus)

H2-M11 [recycling endosome membrane] (Mus musculus)

ENSRNOG00000064836 [recycling endosome membrane] (Rattus norvegicus)

mhc1zda [recycling endosome membrane] (Danio rerio)

DLA-12 [recycling endosome membrane] (Canis familiaris)

H2-M10.6 [recycling endosome membrane] (Mus musculus)

DLA-79 [recycling endosome membrane] (Canis familiaris)

H2-M1 [recycling endosome membrane] (Mus musculus)

RT1-CE16 [recycling endosome membrane] (Rattus norvegicus)

LOC119876868 [recycling endosome membrane] (Canis familiaris)

SLA-7 [recycling endosome membrane] (Sus scrofa)

RT1-CE1 [recycling endosome membrane] (Rattus norvegicus)

mhc1laa [recycling endosome membrane] (Danio rerio)

mhc1zea [recycling endosome membrane] (Danio rerio)

RT1-N3 [recycling endosome membrane] (Rattus norvegicus)

AABR07044362.1 [recycling endosome membrane] (Rattus norvegicus)

H2-Q6 [recycling endosome membrane] (Mus musculus)

Cross References

OpenTargets

ENSG00000206341

PRO

P01893

Pharos - Targets

P01893

GlyGen

P01893

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.558	2

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