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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
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Diseases
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OA [mitochondrial matrix]
Stable Identifier
R-ALL-113587
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Oxaloacetate, OAA, oxaloacetic acid, Oxalacetic acid, 2-oxobutanedioic acid, Oxosuccinic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
CS acetylates OA to citrate (Bos taurus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Bos taurus)
OA [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Bos taurus)
CSKMT methylates Citrate Synthase (Bos taurus)
OA [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
FAHD1 dimer hydrolyses OA to PYR (Bos taurus)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Bos taurus)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Bos taurus)
Respiratory electron transport (Bos taurus)
Malate-aspartate shuttle (Bos taurus)
GOT2 transaminates OA and L-Glu (Bos taurus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Bos taurus)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Bos taurus)
Aspartate and asparagine metabolism (Bos taurus)
GOT2 dimer deaminates L-Asp (Bos taurus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Bos taurus)
GOT2 transaminates OA and L-Glu (Bos taurus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Bos taurus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Bos taurus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PC carboxylates PYR to OA (Bos taurus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Bos taurus)
OA [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
CS acetylates OA to citrate (Caenorhabditis elegans)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Caenorhabditis elegans)
OA [mitochondrial matrix]
Pyruvate metabolism (Caenorhabditis elegans)
FAHD1 dimer hydrolyses OA to PYR (Caenorhabditis elegans)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Caenorhabditis elegans)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Caenorhabditis elegans)
Respiratory electron transport (Caenorhabditis elegans)
Malate-aspartate shuttle (Caenorhabditis elegans)
GOT2 transaminates OA and L-Glu (Caenorhabditis elegans)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Caenorhabditis elegans)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Aspartate and asparagine metabolism (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Caenorhabditis elegans)
GOT2 transaminates OA and L-Glu (Caenorhabditis elegans)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Caenorhabditis elegans)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Caenorhabditis elegans)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PC carboxylates PYR to OA (Caenorhabditis elegans)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Caenorhabditis elegans)
OA [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
CS acetylates OA to citrate (Canis familiaris)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Canis familiaris)
OA [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Canis familiaris)
CSKMT methylates Citrate Synthase (Canis familiaris)
OA [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Canis familiaris)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
Respiratory electron transport (Canis familiaris)
Malate-aspartate shuttle (Canis familiaris)
GOT2 transaminates OA and L-Glu (Canis familiaris)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Canis familiaris)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Canis familiaris)
Aspartate and asparagine metabolism (Canis familiaris)
GOT2 dimer deaminates L-Asp (Canis familiaris)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Canis familiaris)
GOT2 transaminates OA and L-Glu (Canis familiaris)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Canis familiaris)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Canis familiaris)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PC carboxylates PYR to OA (Canis familiaris)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Canis familiaris)
OA [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
CS acetylates OA to citrate (Danio rerio)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Danio rerio)
OA [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Danio rerio)
CSKMT methylates Citrate Synthase (Danio rerio)
OA [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
FAHD1 dimer hydrolyses OA to PYR (Danio rerio)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Danio rerio)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Danio rerio)
Respiratory electron transport (Danio rerio)
Malate-aspartate shuttle (Danio rerio)
GOT2 transaminates OA and L-Glu (Danio rerio)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Danio rerio)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Danio rerio)
Aspartate and asparagine metabolism (Danio rerio)
GOT2 dimer deaminates L-Asp (Danio rerio)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Danio rerio)
GOT2 transaminates OA and L-Glu (Danio rerio)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Danio rerio)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Danio rerio)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PC carboxylates PYR to OA (Danio rerio)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Danio rerio)
OA [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
CS acetylates OA to citrate (Dictyostelium discoideum)
OA [mitochondrial matrix]
Pyruvate metabolism (Dictyostelium discoideum)
FAHD1 dimer hydrolyses OA to PYR (Dictyostelium discoideum)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Dictyostelium discoideum)
Respiratory electron transport (Dictyostelium discoideum)
Malate-aspartate shuttle (Dictyostelium discoideum)
GOT2 transaminates OA and L-Glu (Dictyostelium discoideum)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Aspartate and asparagine metabolism (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Dictyostelium discoideum)
GOT2 transaminates OA and L-Glu (Dictyostelium discoideum)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Dictyostelium discoideum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Dictyostelium discoideum)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
PCK2 phosphorylates OA to yield PEP (Dictyostelium discoideum)
OA [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
CS acetylates OA to citrate (Drosophila melanogaster)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Drosophila melanogaster)
OA [mitochondrial matrix]
Pyruvate metabolism (Drosophila melanogaster)
FAHD1 dimer hydrolyses OA to PYR (Drosophila melanogaster)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Drosophila melanogaster)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Drosophila melanogaster)
Respiratory electron transport (Drosophila melanogaster)
Malate-aspartate shuttle (Drosophila melanogaster)
GOT2 transaminates OA and L-Glu (Drosophila melanogaster)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Drosophila melanogaster)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Aspartate and asparagine metabolism (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Drosophila melanogaster)
GOT2 transaminates OA and L-Glu (Drosophila melanogaster)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Drosophila melanogaster)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PC carboxylates PYR to OA (Drosophila melanogaster)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Drosophila melanogaster)
OA [mitochondrial matrix]
Metabolism (Gallus gallus)
Amino acid metabolism (Gallus gallus)
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
OA [mitochondrial matrix]
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
OA [mitochondrial matrix]
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
OA [mitochondrial matrix]
Lipid metabolism (Gallus gallus)
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
OA [mitochondrial matrix]
The tricarboxylic acid cycle (Gallus gallus)
acetyl-CoA + H2O + oxaloacetate => citrate + CoA (Gallus gallus)
OA [mitochondrial matrix]
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
OA [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
CS acetylates OA to citrate (Homo sapiens)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Homo sapiens)
OA [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
CSKMT methylates Citrate Synthase (Homo sapiens)
OA [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Homo sapiens)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Homo sapiens)
Respiratory electron transport (Homo sapiens)
Malate-aspartate shuttle (Homo sapiens)
GOT2 transaminates OA and L-Glu (Homo sapiens)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Homo sapiens)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Homo sapiens)
Aspartate and asparagine metabolism (Homo sapiens)
GOT2 dimer deaminates L-Asp (Homo sapiens)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Homo sapiens)
GOT2 transaminates OA and L-Glu (Homo sapiens)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Homo sapiens)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Homo sapiens)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PC carboxylates PYR to OA (Homo sapiens)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Homo sapiens)
OA [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
CS acetylates OA to citrate (Mus musculus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Mus musculus)
OA [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
FAHD1 dimer hydrolyses OA to PYR (Mus musculus)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Mus musculus)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Mus musculus)
Respiratory electron transport (Mus musculus)
Malate-aspartate shuttle (Mus musculus)
GOT2 transaminates OA and L-Glu (Mus musculus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Mus musculus)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Mus musculus)
Aspartate and asparagine metabolism (Mus musculus)
GOT2 dimer deaminates L-Asp (Mus musculus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Mus musculus)
GOT2 transaminates OA and L-Glu (Mus musculus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Mus musculus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Mus musculus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PC carboxylates PYR to OA (Mus musculus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Mus musculus)
OA [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
CS acetylates OA to citrate (Plasmodium falciparum)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Plasmodium falciparum)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Plasmodium falciparum)
Respiratory electron transport (Plasmodium falciparum)
Malate-aspartate shuttle (Plasmodium falciparum)
MDH2 dimer dehydrogenates MAL (Plasmodium falciparum)
OA [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
CS acetylates OA to citrate (Rattus norvegicus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Rattus norvegicus)
OA [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
FAHD1 dimer hydrolyses OA to PYR (Rattus norvegicus)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Rattus norvegicus)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Rattus norvegicus)
Respiratory electron transport (Rattus norvegicus)
Malate-aspartate shuttle (Rattus norvegicus)
GOT2 transaminates OA and L-Glu (Rattus norvegicus)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Rattus norvegicus)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Aspartate and asparagine metabolism (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Rattus norvegicus)
GOT2 transaminates OA and L-Glu (Rattus norvegicus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Rattus norvegicus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PC carboxylates PYR to OA (Rattus norvegicus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Rattus norvegicus)
OA [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
CS acetylates OA to citrate (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Pyruvate metabolism (Saccharomyces cerevisiae)
FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Saccharomyces cerevisiae)
Respiratory electron transport (Saccharomyces cerevisiae)
Malate-aspartate shuttle (Saccharomyces cerevisiae)
GOT2 transaminates OA and L-Glu (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Aspartate and asparagine metabolism (Saccharomyces cerevisiae)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
GOT2 transaminates OA and L-Glu (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Saccharomyces cerevisiae)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
CS acetylates OA to citrate (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Pyruvate metabolism (Schizosaccharomyces pombe)
FAHD1 dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Schizosaccharomyces pombe)
Respiratory electron transport (Schizosaccharomyces pombe)
Malate-aspartate shuttle (Schizosaccharomyces pombe)
GOT2 transaminates OA and L-Glu (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Aspartate and asparagine metabolism (Schizosaccharomyces pombe)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
GOT2 transaminates OA and L-Glu (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Schizosaccharomyces pombe)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
CS acetylates OA to citrate (Sus scrofa)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Sus scrofa)
OA [mitochondrial matrix]
Maturation of TCA enzymes and regulation of TCA cycle (Sus scrofa)
CSKMT methylates Citrate Synthase (Sus scrofa)
OA [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Sus scrofa)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Sus scrofa)
Respiratory electron transport (Sus scrofa)
Malate-aspartate shuttle (Sus scrofa)
GOT2 transaminates OA and L-Glu (Sus scrofa)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Sus scrofa)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Sus scrofa)
Aspartate and asparagine metabolism (Sus scrofa)
GOT2 dimer deaminates L-Asp (Sus scrofa)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Sus scrofa)
GOT2 transaminates OA and L-Glu (Sus scrofa)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Sus scrofa)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Sus scrofa)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PC carboxylates PYR to OA (Sus scrofa)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Sus scrofa)
OA [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
CS acetylates OA to citrate (Xenopus tropicalis)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Xenopus tropicalis)
OA [mitochondrial matrix]
Pyruvate metabolism (Xenopus tropicalis)
FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)
OA [mitochondrial matrix]
PC carboxylates PYR to OA (Xenopus tropicalis)
OA [mitochondrial matrix]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Xenopus tropicalis)
Respiratory electron transport (Xenopus tropicalis)
Malate-aspartate shuttle (Xenopus tropicalis)
GOT2 transaminates OA and L-Glu (Xenopus tropicalis)
OA [mitochondrial matrix]
MDH2 dimer dehydrogenates MAL (Xenopus tropicalis)
OA [mitochondrial matrix]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Aspartate and asparagine metabolism (Xenopus tropicalis)
GOT2 dimer deaminates L-Asp (Xenopus tropicalis)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Xenopus tropicalis)
GOT2 transaminates OA and L-Glu (Xenopus tropicalis)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Xenopus tropicalis)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Xenopus tropicalis)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
PC carboxylates PYR to OA (Xenopus tropicalis)
OA [mitochondrial matrix]
External Reference Information
External Reference
oxaloacetate(2-) [ChEBI:16452]
Participates
as an input of
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
acetyl-CoA + H2O + oxaloacetate => citrate + CoA (Gallus gallus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Saccharomyces cerevisiae)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Schizosaccharomyces pombe)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Dictyostelium discoideum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Caenorhabditis elegans)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Drosophila melanogaster)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Gallus gallus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Xenopus tropicalis)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Danio rerio)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Sus scrofa)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Bos taurus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Canis familiaris)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Mus musculus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Homo sapiens)
GOT2 transaminates OA and L-Glu (Schizosaccharomyces pombe)
CS acetylates OA to citrate (Plasmodium falciparum)
PCK2 phosphorylates OA to yield PEP (Dictyostelium discoideum)
PCK2 phosphorylates OA to yield PEP (Caenorhabditis elegans)
PCK2 phosphorylates OA to yield PEP (Drosophila melanogaster)
PCK2 phosphorylates OA to yield PEP (Gallus gallus)
PCK2 phosphorylates OA to yield PEP (Danio rerio)
PCK2 phosphorylates OA to yield PEP (Sus scrofa)
PCK2 phosphorylates OA to yield PEP (Bos taurus)
PCK2 phosphorylates OA to yield PEP (Canis familiaris)
PCK2 phosphorylates OA to yield PEP (Rattus norvegicus)
PCK2 phosphorylates OA to yield PEP (Homo sapiens)
CS acetylates OA to citrate (Gallus gallus)
CS acetylates OA to citrate (Xenopus tropicalis)
CS acetylates OA to citrate (Danio rerio)
CS acetylates OA to citrate (Dictyostelium discoideum)
CS acetylates OA to citrate (Schizosaccharomyces pombe)
FAHD1 dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
FAHD1 dimer hydrolyses OA to PYR (Dictyostelium discoideum)
FAHD1 dimer hydrolyses OA to PYR (Gallus gallus)
CS acetylates OA to citrate (Saccharomyces cerevisiae)
FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
GOT2 transaminates OA and L-Glu (Saccharomyces cerevisiae)
GOT2 transaminates OA and L-Glu (Dictyostelium discoideum)
CS acetylates OA to citrate (Caenorhabditis elegans)
FAHD1 dimer hydrolyses OA to PYR (Caenorhabditis elegans)
GOT2 transaminates OA and L-Glu (Caenorhabditis elegans)
GOT2 transaminates OA and L-Glu (Gallus gallus)
FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)
GOT2 transaminates OA and L-Glu (Xenopus tropicalis)
GOT2 transaminates OA and L-Glu (Bos taurus)
GOT2 transaminates OA and L-Glu (Drosophila melanogaster)
FAHD1 dimer hydrolyses OA to PYR (Drosophila melanogaster)
CS acetylates OA to citrate (Drosophila melanogaster)
GOT2 transaminates OA and L-Glu (Danio rerio)
PCK2 phosphorylates OA to yield PEP (Mus musculus)
CS acetylates OA to citrate (Mus musculus)
GOT2 transaminates OA and L-Glu (Mus musculus)
GOT2 transaminates OA and L-Glu (Homo sapiens)
GOT2 transaminates OA and L-Glu (Rattus norvegicus)
CS acetylates OA to citrate (Rattus norvegicus)
CS acetylates OA to citrate (Homo sapiens)
GOT2 transaminates OA and L-Glu (Canis familiaris)
CS acetylates OA to citrate (Canis familiaris)
CS acetylates OA to citrate (Bos taurus)
FAHD1 dimer hydrolyses OA to PYR (Bos taurus)
CS acetylates OA to citrate (Sus scrofa)
GOT2 transaminates OA and L-Glu (Sus scrofa)
FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)
FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)
FAHD1 dimer hydrolyses OA to PYR (Mus musculus)
FAHD1 dimer hydrolyses OA to PYR (Rattus norvegicus)
FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)
FAHD1 dimer hydrolyses OA to PYR (Danio rerio)
as an output of
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
MDH2 dimer dehydrogenates MAL (Plasmodium falciparum)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
MDH2 dimer dehydrogenates MAL (Schizosaccharomyces pombe)
MDH2 dimer dehydrogenates MAL (Saccharomyces cerevisiae)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
MDH2 dimer dehydrogenates MAL (Caenorhabditis elegans)
PC carboxylates PYR to OA (Caenorhabditis elegans)
MDH2 dimer dehydrogenates MAL (Gallus gallus)
PC carboxylates PYR to OA (Xenopus tropicalis)
MDH2 dimer dehydrogenates MAL (Xenopus tropicalis)
MDH2 dimer dehydrogenates MAL (Drosophila melanogaster)
PC carboxylates PYR to OA (Drosophila melanogaster)
PC carboxylates PYR to OA (Danio rerio)
MDH2 dimer dehydrogenates MAL (Danio rerio)
PC carboxylates PYR to OA (Mus musculus)
MDH2 dimer dehydrogenates MAL (Mus musculus)
GOT2 dimer deaminates L-Asp (Homo sapiens)
GOT2 dimer deaminates L-Asp (Mus musculus)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Canis familiaris)
GOT2 dimer deaminates L-Asp (Bos taurus)
GOT2 dimer deaminates L-Asp (Sus scrofa)
GOT2 dimer deaminates L-Asp (Danio rerio)
GOT2 dimer deaminates L-Asp (Xenopus tropicalis)
GOT2 dimer deaminates L-Asp (Gallus gallus)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
MDH2 dimer dehydrogenates MAL (Homo sapiens)
PC carboxylates PYR to OA (Rattus norvegicus)
MDH2 dimer dehydrogenates MAL (Rattus norvegicus)
PC carboxylates PYR to OA (Homo sapiens)
MDH2 dimer dehydrogenates MAL (Canis familiaris)
PC carboxylates PYR to OA (Canis familiaris)
PC carboxylates PYR to OA (Bos taurus)
MDH2 dimer dehydrogenates MAL (Bos taurus)
MDH2 dimer dehydrogenates MAL (Sus scrofa)
PC carboxylates PYR to OA (Sus scrofa)
This entity regulates
Negatively
CSKMT methylates Citrate Synthase
(Homo sapiens)
CSKMT methylates Citrate Synthase
(Danio rerio)
CSKMT methylates Citrate Synthase
(Bos taurus)
CSKMT methylates Citrate Synthase
(Canis familiaris)
CSKMT methylates Citrate Synthase
(Sus scrofa)
Other forms of this molecule
OA [peroxisomal matrix]
OA [cytosol]
Cross References
AraCyc
OXALACETIC_ACID
CAS
328-42-7
COMPOUND
C00036
PubChem Compound
164550
,
164550
ZINC
000001532521
KEGG Gene
C00036
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