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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
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Analysis Gene Expression
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Diseases
Cytomics
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Ca2+ [Golgi lumen]
Stable Identifier
R-ALL-167012
Type
Chemical Compound [SimpleEntity]
Compartment
Golgi lumen
Synonyms
Calcium, calcium(2+)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide catabolism (Bos taurus)
Phosphate bond hydrolysis by NTPDase proteins (Bos taurus)
NTPDase4 hydrolyzes nucleoside diphosphates (Bos taurus)
NTPDase4:Ca2+ [Golgi membrane] (Bos taurus)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Bos taurus)
NTPDase4:Ca2+ [Golgi membrane] (Bos taurus)
Ca2+ [Golgi lumen]
Metabolism of proteins (Bos taurus)
Peptide hormone metabolism (Bos taurus)
Insulin processing (Bos taurus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Bos taurus)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Bos taurus)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Bos taurus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Bos taurus)
Ca2+ [Golgi lumen]
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by NTRKs (Bos taurus)
Expression and Processing of Neurotrophins (Bos taurus)
NGF processing (Bos taurus)
Part of pro-beta-NGF is processed to mature beta-NGF (Bos taurus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Bos taurus)
Ca2+ [Golgi lumen]
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Ion transport by P-type ATPases (Bos taurus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Bos taurus)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Bos taurus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Sodium/Calcium exchangers (Bos taurus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Bos taurus)
Ca2+ [Golgi lumen]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide catabolism (Caenorhabditis elegans)
Phosphate bond hydrolysis by NTPDase proteins (Caenorhabditis elegans)
NTPDase4 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)
NTPDase4:Ca2+ [Golgi membrane] (Caenorhabditis elegans)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Caenorhabditis elegans)
NTPDase4:Ca2+ [Golgi membrane] (Caenorhabditis elegans)
Ca2+ [Golgi lumen]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Ion transport by P-type ATPases (Caenorhabditis elegans)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Caenorhabditis elegans)
Ca2+ [Golgi lumen]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide catabolism (Canis familiaris)
Phosphate bond hydrolysis by NTPDase proteins (Canis familiaris)
NTPDase4 hydrolyzes nucleoside diphosphates (Canis familiaris)
NTPDase4:Ca2+ [Golgi membrane] (Canis familiaris)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Canis familiaris)
NTPDase4:Ca2+ [Golgi membrane] (Canis familiaris)
Ca2+ [Golgi lumen]
Metabolism of proteins (Canis familiaris)
Peptide hormone metabolism (Canis familiaris)
Insulin processing (Canis familiaris)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Canis familiaris)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Canis familiaris)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Canis familiaris)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Canis familiaris)
Ca2+ [Golgi lumen]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Expression and Processing of Neurotrophins (Canis familiaris)
NGF processing (Canis familiaris)
Part of pro-beta-NGF is processed to mature beta-NGF (Canis familiaris)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Canis familiaris)
Ca2+ [Golgi lumen]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Ion transport by P-type ATPases (Canis familiaris)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Canis familiaris)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Sodium/Calcium exchangers (Canis familiaris)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Canis familiaris)
Ca2+ [Golgi lumen]
Metabolism of proteins (Danio rerio)
Peptide hormone metabolism (Danio rerio)
Insulin processing (Danio rerio)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Danio rerio)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Danio rerio)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Danio rerio)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Danio rerio)
Ca2+ [Golgi lumen]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by NTRKs (Danio rerio)
Expression and Processing of Neurotrophins (Danio rerio)
NGF processing (Danio rerio)
Part of pro-beta-NGF is processed to mature beta-NGF (Danio rerio)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Danio rerio)
Ca2+ [Golgi lumen]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Ion transport by P-type ATPases (Drosophila melanogaster)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Drosophila melanogaster)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Sodium/Calcium exchangers (Drosophila melanogaster)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Drosophila melanogaster)
Ca2+ [Golgi lumen]
Metabolism (Gallus gallus)
Metabolism of nucleotides (Gallus gallus)
Nucleotide catabolism (Gallus gallus)
Phosphate bond hydrolysis by NTPDase proteins (Gallus gallus)
NTPDase4 hydrolyzes nucleoside diphosphates (Gallus gallus)
NTPDase4:Ca2+ [Golgi membrane] (Gallus gallus)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Gallus gallus)
NTPDase4:Ca2+ [Golgi membrane] (Gallus gallus)
Ca2+ [Golgi lumen]
Metabolism of proteins (Gallus gallus)
Peptide hormone metabolism (Gallus gallus)
Insulin processing (Gallus gallus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Gallus gallus)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Gallus gallus)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Gallus gallus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Gallus gallus)
Ca2+ [Golgi lumen]
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by NTRKs (Gallus gallus)
Expression and Processing of Neurotrophins (Gallus gallus)
NGF processing (Gallus gallus)
Part of pro-beta-NGF is processed to mature beta-NGF (Gallus gallus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Gallus gallus)
Ca2+ [Golgi lumen]
Transport of small molecules (Gallus gallus)
Ion channel transport (Gallus gallus)
Ion transport by P-type ATPases (Gallus gallus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Sodium/Calcium exchangers (Gallus gallus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Gallus gallus)
Ca2+ [Golgi lumen]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6) (Homo sapiens)
Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)
Ca2+ [Golgi lumen]
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
SARS-CoV-2 E pentamer transports Ca2+ (Homo sapiens)
Ca2+ [Golgi lumen]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Phosphate bond hydrolysis by NTPDase proteins (Homo sapiens)
NTPDase4 hydrolyzes nucleoside diphosphates (Homo sapiens)
NTPDase4:Ca2+ [Golgi membrane] (Homo sapiens)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Homo sapiens)
NTPDase4:Ca2+ [Golgi membrane] (Homo sapiens)
Ca2+ [Golgi lumen]
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Insulin processing (Homo sapiens)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Homo sapiens)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Homo sapiens)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Homo sapiens)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Homo sapiens)
Ca2+ [Golgi lumen]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Expression and Processing of Neurotrophins (Homo sapiens)
NGF processing (Homo sapiens)
Part of pro-beta-NGF is processed to mature beta-NGF (Homo sapiens)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Homo sapiens)
Ca2+ [Golgi lumen]
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Sodium/Calcium exchangers (Homo sapiens)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)
Ca2+ [Golgi lumen]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide catabolism (Mus musculus)
Phosphate bond hydrolysis by NTPDase proteins (Mus musculus)
NTPDase4 hydrolyzes nucleoside diphosphates (Mus musculus)
NTPDase4:Ca2+ [Golgi membrane] (Mus musculus)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Mus musculus)
NTPDase4:Ca2+ [Golgi membrane] (Mus musculus)
Ca2+ [Golgi lumen]
Metabolism of proteins (Mus musculus)
Peptide hormone metabolism (Mus musculus)
Insulin processing (Mus musculus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Mus musculus)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Mus musculus)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Mus musculus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Mus musculus)
Ca2+ [Golgi lumen]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by NTRKs (Mus musculus)
Expression and Processing of Neurotrophins (Mus musculus)
NGF processing (Mus musculus)
Part of pro-beta-NGF is processed to mature beta-NGF (Mus musculus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Mus musculus)
Ca2+ [Golgi lumen]
Transport of small molecules (Mus musculus)
Ion channel transport (Mus musculus)
Ion transport by P-type ATPases (Mus musculus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Mus musculus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Sodium/Calcium exchangers (Mus musculus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Mus musculus)
Ca2+ [Golgi lumen]
Transport of small molecules (Plasmodium falciparum)
Ion channel transport (Plasmodium falciparum)
Ion transport by P-type ATPases (Plasmodium falciparum)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Plasmodium falciparum)
Ca2+ [Golgi lumen]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide catabolism (Rattus norvegicus)
Phosphate bond hydrolysis by NTPDase proteins (Rattus norvegicus)
NTPDase4 hydrolyzes nucleoside diphosphates (Rattus norvegicus)
NTPDase4:Ca2+ [Golgi membrane] (Rattus norvegicus)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Rattus norvegicus)
NTPDase4:Ca2+ [Golgi membrane] (Rattus norvegicus)
Ca2+ [Golgi lumen]
Metabolism of proteins (Rattus norvegicus)
Peptide hormone metabolism (Rattus norvegicus)
Insulin processing (Rattus norvegicus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Rattus norvegicus)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Rattus norvegicus)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Rattus norvegicus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Rattus norvegicus)
Ca2+ [Golgi lumen]
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by NTRKs (Rattus norvegicus)
Expression and Processing of Neurotrophins (Rattus norvegicus)
NGF processing (Rattus norvegicus)
Part of pro-beta-NGF is processed to mature beta-NGF (Rattus norvegicus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Rattus norvegicus)
Ca2+ [Golgi lumen]
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Ion transport by P-type ATPases (Rattus norvegicus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Rattus norvegicus)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Sodium/Calcium exchangers (Rattus norvegicus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Rattus norvegicus)
Ca2+ [Golgi lumen]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide catabolism (Saccharomyces cerevisiae)
Phosphate bond hydrolysis by NTPDase proteins (Saccharomyces cerevisiae)
NTPDase4 hydrolyzes nucleoside diphosphates (Saccharomyces cerevisiae)
NTPDase4:Ca2+ [Golgi membrane] (Saccharomyces cerevisiae)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Saccharomyces cerevisiae)
NTPDase4:Ca2+ [Golgi membrane] (Saccharomyces cerevisiae)
Ca2+ [Golgi lumen]
Transport of small molecules (Saccharomyces cerevisiae)
Ion channel transport (Saccharomyces cerevisiae)
Ion transport by P-type ATPases (Saccharomyces cerevisiae)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Saccharomyces cerevisiae)
Ca2+ [Golgi lumen]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide catabolism (Schizosaccharomyces pombe)
Phosphate bond hydrolysis by NTPDase proteins (Schizosaccharomyces pombe)
NTPDase4 hydrolyzes nucleoside diphosphates (Schizosaccharomyces pombe)
NTPDase4:Ca2+ [Golgi membrane] (Schizosaccharomyces pombe)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Schizosaccharomyces pombe)
NTPDase4:Ca2+ [Golgi membrane] (Schizosaccharomyces pombe)
Ca2+ [Golgi lumen]
Transport of small molecules (Schizosaccharomyces pombe)
Ion channel transport (Schizosaccharomyces pombe)
Ion transport by P-type ATPases (Schizosaccharomyces pombe)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)
Ca2+ [Golgi lumen]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide catabolism (Sus scrofa)
Phosphate bond hydrolysis by NTPDase proteins (Sus scrofa)
NTPDase4 hydrolyzes nucleoside diphosphates (Sus scrofa)
NTPDase4:Ca2+ [Golgi membrane] (Sus scrofa)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Sus scrofa)
NTPDase4:Ca2+ [Golgi membrane] (Sus scrofa)
Ca2+ [Golgi lumen]
Metabolism of proteins (Sus scrofa)
Peptide hormone metabolism (Sus scrofa)
Insulin processing (Sus scrofa)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Sus scrofa)
Ca2+ [Golgi lumen]
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Sus scrofa)
Ca2+ [Golgi lumen]
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Sus scrofa)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Sus scrofa)
Ca2+ [Golgi lumen]
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Expression and Processing of Neurotrophins (Sus scrofa)
NGF processing (Sus scrofa)
Part of pro-beta-NGF is processed to mature beta-NGF (Sus scrofa)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Sus scrofa)
Ca2+ [Golgi lumen]
Transport of small molecules (Sus scrofa)
Ion channel transport (Sus scrofa)
Ion transport by P-type ATPases (Sus scrofa)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Sus scrofa)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of inorganic cations/anions and amino acids/oligopeptides (Sus scrofa)
Sodium/Calcium exchangers (Sus scrofa)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Sus scrofa)
Ca2+ [Golgi lumen]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide catabolism (Xenopus tropicalis)
Phosphate bond hydrolysis by NTPDase proteins (Xenopus tropicalis)
NTPDase4 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)
NTPDase4:Ca2+ [Golgi membrane] (Xenopus tropicalis)
Ca2+ [Golgi lumen]
NTPDase4 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)
NTPDase4:Ca2+ [Golgi membrane] (Xenopus tropicalis)
Ca2+ [Golgi lumen]
Metabolism of proteins (Xenopus tropicalis)
Peptide hormone metabolism (Xenopus tropicalis)
Insulin processing (Xenopus tropicalis)
Proinsulin:Zinc:Calcium complex translocates to immature secretory granule (Xenopus tropicalis)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Xenopus tropicalis)
Ca2+ [Golgi lumen]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by NTRKs (Xenopus tropicalis)
Expression and Processing of Neurotrophins (Xenopus tropicalis)
NGF processing (Xenopus tropicalis)
Part of pro-beta-NGF is processed to mature beta-NGF (Xenopus tropicalis)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Xenopus tropicalis)
Ca2+ [Golgi lumen]
Transport of small molecules (Xenopus tropicalis)
Ion channel transport (Xenopus tropicalis)
Ion transport by P-type ATPases (Xenopus tropicalis)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Xenopus tropicalis)
Ca2+ [Golgi lumen]
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Sodium/Calcium exchangers (Xenopus tropicalis)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Xenopus tropicalis)
Ca2+ [Golgi lumen]
External Reference Information
External Reference
calcium(2+) [ChEBI:29108]
Participates
as a component of
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Rattus norvegicus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Mus musculus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Canis familiaris)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Sus scrofa)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Xenopus tropicalis)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Danio rerio)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Gallus gallus)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Bos taurus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Bos taurus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Homo sapiens)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Rattus norvegicus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Canis familiaris)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Sus scrofa)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Gallus gallus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Mus musculus)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Xenopus tropicalis)
Subtilisin/kexin convertase (Calcium dependant) [Golgi lumen] (Danio rerio)
NTPDase4:Ca2+ [Golgi membrane] (Schizosaccharomyces pombe)
NTPDase4:Ca2+ [Golgi membrane] (Homo sapiens)
NTPDase4:Ca2+ [Golgi membrane] (Rattus norvegicus)
NTPDase4:Ca2+ [Golgi membrane] (Gallus gallus)
NTPDase4:Ca2+ [Golgi membrane] (Mus musculus)
NTPDase4:Ca2+ [Golgi membrane] (Xenopus tropicalis)
NTPDase4:Ca2+ [Golgi membrane] (Caenorhabditis elegans)
NTPDase4:Ca2+ [Golgi membrane] (Saccharomyces cerevisiae)
NTPDase4:Ca2+ [Golgi membrane] (Sus scrofa)
NTPDase4:Ca2+ [Golgi membrane] (Bos taurus)
NTPDase4:Ca2+ [Golgi membrane] (Canis familiaris)
6xProinsulin:2xZn2+:1xCa2+ [Golgi lumen] (Homo sapiens)
as an input of
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Gallus gallus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Danio rerio)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Sus scrofa)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Bos taurus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Canis familiaris)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Rattus norvegicus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Mus musculus)
Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Homo sapiens)
SARS-CoV-2 E pentamer transports Ca2+ (Homo sapiens)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Mus musculus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Rattus norvegicus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Canis familiaris)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Bos taurus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Sus scrofa)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Xenopus tropicalis)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Gallus gallus)
SLC24A5 exchanges cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Drosophila melanogaster)
Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)
as an output of
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Rattus norvegicus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Canis familiaris)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Bos taurus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Sus scrofa)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Xenopus tropicalis)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Drosophila melanogaster)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Caenorhabditis elegans)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Saccharomyces cerevisiae)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Plasmodium falciparum)
Other forms of this molecule
Ca2+ [platelet dense granule lumen]
Ca2+ [endosome membrane]
Ca2+ [sarcoplasmic reticulum lumen]
Ca2+ [mitochondrial intermembrane space]
Ca2+ [lysosomal lumen]
Ca2+ [endocytic vesicle lumen]
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
Ca2+ [platelet dense tubular network lumen]
Ca2+ [platelet dense tubular network membrane]
Ca2+ [plasma membrane]
Ca2+ [secretory granule lumen]
Ca2+ [nuclear envelope]
Ca2+ [nucleoplasm]
Ca2+ [mitochondrial matrix]
Ca2+ [mitochondrial inner membrane]
Ca2+ [endoplasmic reticulum membrane]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Ca2+ [endoplasmic reticulum lumen]
Cross References
COMPOUND
C00076
PubChem Substance
8145461
HMDB Metabolite
HMDB0000464
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