Reactome | RPN2 [endoplasmic reticulum membrane]

RPN2 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-264937

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P04844 RPN2

Gene Names

RPN2

Chain

signal peptide:1-22, chain:23-631

Reference Genes

BioGPS Gene:6185 RPN2

COSMIC (genes):RPN2 RPN2

CTD Gene:6185 RPN2

dbSNP Gene:6185 RPN2

ENSEMBL:ENSG00000118705 RPN2

HGNC:10382 RPN2

KEGG Gene (Homo sapiens):6185 RPN2

Monarch:6185 RPN2

NCBI Gene:6185 RPN2

OMIM:180490 RPN2

UCSC:P04844 RPN2

Reference Transcript

Other Identifiers

0002480706

11715660_a_at

16913378

208689_s_at

213399_x_at

213491_x_at

36676_at

3884102

3884103

3884105

3884108

3884110

3884117

3884118

3884119

3884120

3884121

3884123

3884124

3884129

3884130

3884134

3884136

3884137

3884138

3884143

3884146

3884147

3884148

3884149

6185

69127_at

8062349

A_23_P108994

A_33_P3240258

A_33_P3332145

GE81214

GO:0000421

GO:0003674

GO:0004579

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005773

GO:0005783

GO:0005789

GO:0005791

GO:0006464

GO:0006486

GO:0006487

GO:0007568

GO:0008150

GO:0008250

GO:0009058

GO:0016020

GO:0016021

GO:0016604

GO:0016757

GO:0018279

GO:0019082

GO:0032991

GO:0042493

GO:0043022

GO:0043226

GO:0044403

HMNXSV003027642

ILMN_1693421

TC20000271.hg

Y00282_at

g13097707_3p_a_at

Participates

as a component of

Cross References

RefSeq

NP_002942.2, NP_001129243.1, NP_001311234.1, NP_001311233.1, NP_001311232.1, NP_001311228.1, NP_001311231.1, NP_001311230.1, NP_001311235.1

OpenTargets

ENSG00000118705

GeneCards

P04844

HPA

ENSG00000118705-RPN2

Ensembl

ENSP00000362724, ENST00000373622, ENSP00000237530, ENST00000237530, ENSG00000118705

PRO

P04844

Pharos - Targets

P04844

GlyGen

P04844

PDB

6S7O, 6S7T

HMDB Protein

HMDBP01592

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27824 CANX	2	CANX [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.569	3
UniProt:Q14165 MLEC	3	MLEC [specific granule membrane] (R-HSA-6799618) MLEC [plasma membrane] (R-HSA-6806292) MLEC [endoplasmic reticulum membrane] (R-HSA-901082)	0.564	2
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.462	2