Reactome | HAT1 [nucleoplasm]

HAT1 [nucleoplasm]

Stable Identifier

R-HSA-3662337

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KAT1, Histone acetyltransferase type B catalytic subunit ecNumber2.3.1.48/ecNumber, HAT1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O14929 HAT1

Gene Names

HAT1, KAT1

Chain

initiator methionine:1, chain:2-419

Reference Genes

BioGPS Gene:8520 HAT1

COSMIC (genes):HAT1 HAT1

CTD Gene:8520 HAT1

dbSNP Gene:8520 HAT1

ENSEMBL:ENSG00000128708 HAT1

ENSEMBL:ENSG00000128708.13 HAT1

HGNC:4821 HAT1

KEGG Gene (Homo sapiens):8520 HAT1

Monarch:8520 HAT1

NCBI Gene:8520 HAT1

OMIM:603053 HAT1

UCSC:O14929 HAT1

Reference Transcript

RefSeq:NM_003642.3 HAT1

Other Identifiers

11723254_a_at

11723255_x_at

16887635

203138_PM_at

203138_at

2515370

2515374

2515375

2515377

2515378

2515383

2515384

2515388

2515390

2515392

2515394

2515397

2515398

2515399

3098233

41855_at

8046346

8520

A_14_P130151

A_23_P339480

GE54236

GO:0000781

GO:0000785

GO:0003824

GO:0004402

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005739

GO:0006325

GO:0006334

GO:0006475

GO:0010485

GO:0016363

GO:0016573

GO:0016740

GO:0016746

GO:0031509

GO:0032200

GO:0032991

GO:0036211

GO:0042393

GO:0043226

GO:0043997

GO:0051276

GO:0065003

GO:0140096

HMNXSV003008227

ILMN_1693905

ILMN_1725244

PH_hs_0001286

TC02003690.hg

g4504340_3p_at

Participates

as a component of

HAT1:RBBP7 [nucleoplasm] (Homo sapiens)

Inferred To

hat-1 [nucleoplasm] (Caenorhabditis elegans)

HAT1 [nucleoplasm] (Bos taurus)

HAT1 [nucleoplasm] (Canis familiaris)

HAT1 [nucleoplasm] (Dictyostelium discoideum)

HAT1 [nucleoplasm] (Gallus gallus)

HAT1 [nucleoplasm] (Mus musculus)

HAT1 [nucleoplasm] (Plasmodium falciparum)

HAT1 [nucleoplasm] (Rattus norvegicus)

HAT1 [nucleoplasm] (Saccharomyces cerevisiae)

HAT1 [nucleoplasm] (Schizosaccharomyces pombe)

HAT1 [nucleoplasm] (Sus scrofa)

hat1 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_003633.1

Guide to Pharmacology - Targets

2657

OpenTargets

ENSG00000128708

HPA

ENSG00000128708-HAT1

GeneCards

O14929

Ensembl

ENSG00000128708, ENST00000264108, ENSP00000264108

PRO

O14929

Pharos - Targets

O14929

HMDB Protein

HMDBP09986

PDB

6VO5, 2P0W

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62805 H4C1	17	polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) HIST1H4A [extracellular region] (R-HSA-977569) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.704	7
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.666	4
UniProt:Q9H5V9 STEEP1	1	STEEP1 [nucleoplasm] (R-HSA-9769596)	0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:Q8NAM6 ZSCAN4	1	ZSCAN4 [nucleoplasm] (R-HSA-9816447)	0.556	3
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.527	2
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm] (R-HSA-417169)	0.527	2

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