Reactome | RBBP7 [nucleoplasm]

RBBP7 [nucleoplasm]

Stable Identifier

R-HSA-212227

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RbAp46

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q16576 RBBP7

Gene Names

RBBP7, RBAP46

Chain

initiator methionine:, chain:2-425, initiator methionine:

Reference Genes

BioGPS Gene:5931 RBBP7

COSMIC (genes):RBBP7 RBBP7

CTD Gene:5931 RBBP7

dbSNP Gene:5931 RBBP7

ENSEMBL:ENSG00000102054 RBBP7

HGNC:9890 RBBP7

KEGG:hsa:5931 RBBP7

Monarch:5931 RBBP7

NCBI Gene:5931 RBBP7

OMIM:300825 RBBP7

UCSC:Q16576 RBBP7

Reference Transcript

Other Identifiers

11715433_a_at

17109396

201092_PM_at

201092_at

3981265

4000945

4000946

4000947

4000948

4000949

4000950

4000951

4000952

4000953

4000955

4000956

4000957

4000958

4000959

4000960

4000961

4000962

4000963

4000966

4000967

4000968

4000969

4000970

4000972

4000973

4000974

4000975

4000976

4000977

4000978

4000979

41515_at

5931

8171516

A_23_P114221

GE59981

GO:0000118

GO:0000122

GO:0000781

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006260

GO:0006325

GO:0006338

GO:0006355

GO:0007420

GO:0016581

GO:0016589

GO:0030308

GO:0030336

GO:0030512

GO:0031491

GO:0035098

GO:0042393

GO:0042659

GO:0043226

GO:0045892

GO:0045893

GO:0048545

GO:0048856

GO:0070370

GO:0070822

GO:1902455

GO:1902459

GO:1904949

GO:2000736

HMNXSV003057994

ILMN_1770053

PH_hs_0019247

TC0X000886.hg

X72841_at

g13259504_3p_at

Participates

as a member of

as a component of

as an input of

Inferred To

Ghost homologue of RBBP7 [nucleoplasm] (Canis familiaris)

Rbbp7 [nucleoplasm] (Mus musculus)

Rbbp7 [nucleoplasm] (Rattus norvegicus)

RBBP7 [nucleoplasm] (Bos taurus)

RBBP7 [nucleoplasm] (Gallus gallus)

RBBP7 [nucleoplasm] (Plasmodium falciparum)

RBBP7 [nucleoplasm] (Sus scrofa)

rbbp7 [nucleoplasm] (Danio rerio)

rbbp7 [nucleoplasm] (Xenopus tropicalis)

mis16 [nucleoplasm] (Schizosaccharomyces pombe)

rbbD [nucleoplasm] (Dictyostelium discoideum)

Homologues of RBBP7 [nucleoplasm] (Plasmodium falciparum)

Caf1-55 [nucleoplasm] (Drosophila melanogaster)

HAT2 [nucleoplasm] (Saccharomyces cerevisiae)

lin-53 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_002884.1, NP_001185648.1

OpenTargets

ENSG00000102054

ENSEMBL

ENSP00000369424, ENST00000380084, ENSP00000369427, ENST00000380087

HPA

ENSG00000102054-RBBP7

PRO

Q16576

Pharos - Targets

Q16576

GlyGen

Q16576

PDB

7M3X, 3CFV, 3CFS

Interactors (71)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O94776 MTA2	1	MTA2 [nucleoplasm] (R-HSA-4657009)	0.911	14
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.909	12
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.837	8
UniProt:Q15022 SUZ12	2	SUZ12 [nucleoplasm] (R-HSA-212217) monoSUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932)	0.837	10
UniProt:P62805 H4C1	17	HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) HIST1H4A [extracellular region] (R-HSA-977569) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531)	0.793	9
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm] (R-HSA-417169)	0.788	6
UniProt:O14519 CDKA1			0.788	7
UniProt:O95983 MBD3	1	MBD3 [nucleoplasm] (R-HSA-4657010)	0.758	7
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.725	7
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) monoSUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.725	6
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.725	6
UniProt:Q8WXI9 GATAD2B	1	GATAD2B [nucleoplasm] (R-HSA-3702079)	0.725	7
UniProt:Q9NVP2 ASF1B			0.725	5
UniProt:O75446 SAP30	1	SAP30 [nucleoplasm] (R-HSA-351693)	0.725	6
UniProt:Q9BTC8 MTA3	1	MTA3 [nucleoplasm] (R-HSA-4657013)	0.725	6
UniProt:P68431 HIST1H3G	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Me1K5-H3C1 [nucleoplasm] (R-HSA-9677683) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135)	0.725	4
UniProt:Q9Y483 MTF2	1	MTF2 [nucleoplasm] (R-HSA-5084119)	0.725	7
UniProt:Q12873 CHD3	2	CHD3 [nucleoplasm] (R-HSA-4657012) monoSUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372)	0.677	8
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.643	6
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.643	7
UniProt:Q9UBB5 MBD2	1	MBD2 [nucleoplasm] (R-HSA-427367)	0.643	5
UniProt:Q6ZN18 AEBP2	1	AEBP2 [nucleoplasm] (R-HSA-5082342)	0.643	5
UniProt:Q5PSV4 BRM1L			0.643	5
UniProt:Q96QT6 PHF12			0.643	5
UniProt:O43189 PHF1	1	PHF1 [nucleoplasm] (R-HSA-5084105)	0.643	4
UniProt:Q9NP50 SHCAF			0.643	5
UniProt:Q86YP4 GATAD2A	1	GATAD2A [nucleoplasm] (R-HSA-3702077)	0.643	5
UniProt:O75182 SIN3B	1	SIN3B [nucleoplasm] (R-HSA-3006450)	0.643	5
UniProt:Q8WUU5 GATD1			0.643	5
UniProt:Q9HAJ7 SAP30L	1	SAP30L [nucleoplasm] (R-HSA-351698)	0.643	5
UniProt:O14929 HAT1	1	HAT1 [nucleoplasm] (R-HSA-3662337)	0.643	5
UniProt:Q9HCU9 BRMS1	1	BRMS1 [nucleoplasm] (R-HSA-4650034)	0.643	5
UniProt:Q92800 EZH1			0.643	3
IntAct:EBI-15650351 H3TAIL			0.591	3
UniProt:Q14839 CHD4	1	CHD4 [nucleoplasm] (R-HSA-3702078)	0.577	7
UniProt:Q9UBU8 MORF4L1	1	MORF4L1 [nucleoplasm] (R-HSA-3321982)	0.527	2
UniProt:Q5T6S3 PHF19	1	PHF19 [nucleoplasm] (R-HSA-5084115)	0.527	3
UniProt:Q8IV32 CCD71			0.527	3
UniProt:Q6ZSJ8 CA122			0.527	3
UniProt:P85037 FOXK1	1	FOXK1 [nucleoplasm] (R-HSA-5689673)	0.527	3
UniProt:Q9H165 BCL11A	2	BCL11A(1-219)insDHPPA-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713447) BCL11A(1-219)insDHPPA-ALK(1058-1620) fusion [cytosol] (R-HSA-9713444)	0.527	3
UniProt:Q01167 FOXK2	1	FOXK2 [nucleoplasm] (R-HSA-5689655)	0.527	3
UniProt:Q8WWY6 MB3L1			0.527	2
UniProt:Q9P2Y4 ZN219			0.527	5
UniProt:A6NHQ4 EPOP			0.527	3
UniProt:Q9P281 BAHC1			0.527	4
UniProt:Q96JN0 LCOR			0.527	2
UniProt:Q8TDI0 CHD5			0.527	4
UniProt:P28370 SMCA1			0.527	3
UniProt:Q14207 NPAT			0.527	3
UniProt:Q9H0E3 SAP130	1	SAP130 [nucleoplasm] (R-HSA-3006732)	0.527	4
UniProt:Q9R190 Mta2	1	Mta2 [nucleoplasm] (R-MMU-5096453)	0.527	2
UniProt:P84243 H3-3A	18	H3F3A [nucleoplasm] (R-HSA-212295) Me2K5-H3F3A [nucleoplasm] (R-HSA-1214206) Me3K-28-H3F3A [nucleoplasm] (R-HSA-212282) Me3K-10-H3F3A [nucleoplasm] (R-HSA-5625747) p-T12,Me3K-10-H3F3A [nucleoplasm] (R-HSA-5625758) p-T12, Me2K-10-H3F3A [nucleoplasm] (R-HSA-5625800) p-T12,MeK-H3F3A [nucleoplasm] (R-HSA-5625858) p-T12-H3F3A [nucleoplasm] (R-HSA-5625878) Me2K-10-H3F3A [nucleoplasm] (R-HSA-427324) Me3K5-H3F3A [nucleoplasm] (R-HSA-1214216) H3F3A [extracellular region] (R-HSA-977567) AcK10-H3F3A [nucleoplasm] (R-HSA-5250654) Me2K5,Me2aR2-H3F3A [nucleoplasm] (R-HSA-8936573) H3R17me2a [nucleoplasm] (R-HSA-9822613) MeK28-H3-3A [nucleoplasm] (R-HSA-9822942) Me1K5-H3-3A [nucleoplasm] (R-HSA-9864864) 2xAcK-H3F3A [nucleoplasm] (R-HSA-427504) MeK-H3F3A [nucleoplasm] (R-HSA-427369)	0.527	2
UniProt:Q8N680 ZBTB2			0.527	3
UniProt:Q96KM6 ZNF512B	1	ZNF512B [cytosol] (R-HSA-9715175)	0.527	3
UniProt:Q9H0W5 CCDC8	1	CCDC8 [cytosol] (R-HSA-8955915)	0.527	3
UniProt:P29375 KDM5A	1	KDM5A [nucleoplasm] (R-HSA-3215029)	0.527	3
UniProt:O60264 SMARCA5	1	SMARCA5 [nucleoplasm] (R-HSA-417140)	0.527	3
UniProt:Q2M1K9 ZNF423	1	ZNF423 [nucleoplasm] (R-HSA-3222318)	0.527	3
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:Q9H160 ING2	2	monoSUMO1-K195-ING2 [nucleoplasm] (R-HSA-4086075) ING2 [nucleoplasm] (R-HSA-3215167)	0.527	4
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	3
UniProt:Q96K83 ZNF521	1	ZNF521 [nucleoplasm] (R-HSA-3222324)	0.527	3
UniProt:Q12830 BPTF			0.527	4
UniProt:Q9H7L9 SUDS3	2	K63polyUb-SUDS3 [nucleoplasm] (R-HSA-6782790) SUDS3 [nucleoplasm] (R-HSA-351696)	0.527	4
UniProt:Q96N64 PWP2A			0.527	2
UniProt:P62799 H4			0.524	2
UniProt:Q17R98 ZN827			0.499	2
UniProt:P12520 VPR			0.462	4
UniProt:Q8N5A5 ZGPAT			0.462	2
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.462	3

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