Reactome | RBBP7 [nucleoplasm]

RBBP7 [nucleoplasm]

Stable Identifier

R-HSA-212227

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RbAp46

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q16576 RBBP7

Gene Names

RBBP7, RBAP46

Chain

initiator methionine:1, initiator methionine:, chain:2-425

Reference Genes

BioGPS Gene:5931 RBBP7

COSMIC (genes):RBBP7 RBBP7

CTD Gene:5931 RBBP7

dbSNP Gene:5931 RBBP7

ENSEMBL:ENSG00000102054 RBBP7

ENSEMBL:ENSG00000102054.18 RBBP7

HGNC:9890 RBBP7

KEGG Gene (Homo sapiens):5931 RBBP7

Monarch:5931 RBBP7

NCBI Gene:5931 RBBP7

OMIM:300825 RBBP7

UCSC:Q16576 RBBP7

Reference Transcript

Other Identifiers

11715433_a_at

17109396

201092_PM_at

201092_at

3981265

4000946

4000947

4000948

4000949

4000951

4000953

4000955

4000958

4000960

4000963

4000966

4000967

4000968

4000970

4000973

4000975

4000976

4000977

4000978

4000979

41515_at

5931

8171516

A_23_P114221

GE59981

GO:0000118

GO:0000122

GO:0000228

GO:0000781

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006260

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0007420

GO:0016575

GO:0016580

GO:0016581

GO:0016589

GO:0023052

GO:0030154

GO:0030308

GO:0030336

GO:0030512

GO:0035098

GO:0036211

GO:0042393

GO:0042659

GO:0043226

GO:0045892

GO:0045893

GO:0048545

GO:0048856

GO:0048870

GO:0070370

GO:1902455

GO:1902459

GO:1904949

GO:2000736

HMNXSV003057994

ILMN_1770053

PH_hs_0019247

TC0X000886.hg

X72841_at

g13259504_3p_at

Participates

as a member of

as a component of

as an input of

Inferred To

Rbbp7 [nucleoplasm] (Mus musculus)

Rbbp7 [nucleoplasm] (Rattus norvegicus)

RBBP7 [nucleoplasm] (Bos taurus)

RBBP7 [nucleoplasm] (Canis familiaris)

RBBP7 [nucleoplasm] (Gallus gallus)

RBBP7 [nucleoplasm] (Plasmodium falciparum)

RBBP7 [nucleoplasm] (Sus scrofa)

rbbp7 [nucleoplasm] (Danio rerio)

rbbp7 [nucleoplasm] (Xenopus tropicalis)

mis16 [nucleoplasm] (Schizosaccharomyces pombe)

rbbD [nucleoplasm] (Dictyostelium discoideum)

Caf1-55 [nucleoplasm] (Drosophila melanogaster)

HAT2 [nucleoplasm] (Saccharomyces cerevisiae)

lin-53 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_002884.1, NP_001185648.1

OpenTargets

ENSG00000102054

HPA

ENSG00000102054-RBBP7

GeneCards

Q16576

Ensembl

ENSG00000102054, ENST00000380084, ENST00000380087, ENSP00000369427, ENSP00000369424

PRO

Q16576

Pharos - Targets

Q16576

PDB

3CFV, 7M3X, 3CFS

Interactors (42)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.886	7
UniProt:O94776 MTA2	1	MTA2 [nucleoplasm] (R-HSA-4657009)	0.88	11
UniProt:P62805 H4C1	17	polySUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) monoSUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) HIST1H4A [extracellular region] (R-HSA-977569) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.793	9
UniProt:Q15022 SUZ12	2	SUZ12 [nucleoplasm] (R-HSA-212217) monoSUMO1-K75-SUZ12 [nucleoplasm] (R-HSA-4615932)	0.788	6
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm] (R-HSA-417169)	0.725	4
UniProt:Q92769 HDAC2	2	monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958) HDAC2 [nucleoplasm] (R-HSA-205135)	0.725	4
UniProt:O14519 CDKA1			0.725	4
UniProt:O95983 MBD3	1	MBD3 [nucleoplasm] (R-HSA-4657010)	0.69	4
UniProt:Q9Y483 MTF2	1	MTF2 [nucleoplasm] (R-HSA-5084119)	0.643	4
UniProt:Q9BTC8 MTA3	1	MTA3 [nucleoplasm] (R-HSA-4657013)	0.643	3
UniProt:O75446 SAP30	1	SAP30 [nucleoplasm] (R-HSA-351693)	0.643	3
UniProt:Q9NVP2 ASF1B			0.643	3
UniProt:P68431 H3C1	20	2xAcK-HIST1H3A [nucleoplasm] (R-HSA-427507) Ack-Me3K5-HIST1H3A [nucleoplasm] (R-HSA-4551293) AcK-Me3K10-HIST1H3A [nucleoplasm] (R-HSA-4551291) AcK-Me3K28-HIST1H3A [nucleoplasm] (R-HSA-4551292) Me2aR27-HIST1H3A [nucleoplasm] (R-HSA-5229052) Me2aR18-HIST1H3A [nucleoplasm] (R-HSA-5229062) Me2sR9-HIST1H3A [nucleoplasm] (R-HSA-5211328) Me2sR3-HIST1H3A [nucleoplasm] (R-HSA-5218935) AcK9,14-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8870893) AcK14,18,79-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871271) AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871306) AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871294) AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8865596) AcK14,18-p-S10-HIST1H3A [nucleoplasm] (R-HSA-8871295) AcK14,18,79-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871288) AcK14,18-p-T11-HIST1H3A [nucleoplasm] (R-HSA-8871299) AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm] (R-HSA-8871286) Me2K28-HIST1H3A [nucleoplasm] (R-HSA-4754193) MeK37-HIST1H3A [nucleoplasm] (R-HSA-4722135) MeK80-HIST1H3A [nucleoplasm] (R-HSA-5649791)	0.643	3
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) monoSUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.643	3
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.643	3
UniProt:Q15910 EZH2	1	EZH2 [nucleoplasm] (R-HSA-212298)	0.643	4
UniProt:Q8WXI9 GATAD2B	1	GATAD2B [nucleoplasm] (R-HSA-3702079)	0.643	3
IntAct:EBI-15650351 H3TAIL			0.591	3
UniProt:Q12873 CHD3	2	CHD3 [nucleoplasm] (R-HSA-4657012) monoSUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372)	0.577	5
UniProt:Q96QT6 PHF12			0.527	2
UniProt:Q5PSV4 BRM1L			0.527	2
UniProt:Q6ZN18 AEBP2	1	AEBP2 [nucleoplasm] (R-HSA-5082342)	0.527	2
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.527	3
UniProt:Q9R190 Mta2	1	Mta2 [nucleoplasm] (R-MMU-5096453)	0.527	2
UniProt:Q92800 EZH1			0.527	2
UniProt:Q9HCU9 BRMS1	1	BRMS1 [nucleoplasm] (R-HSA-4650034)	0.527	2
UniProt:O14929 HAT1	1	HAT1 [nucleoplasm] (R-HSA-3662337)	0.527	2
UniProt:Q9HAJ7 SAP30L	1	SAP30L [nucleoplasm] (R-HSA-351698)	0.527	2
UniProt:Q8WUU5 GATD1			0.527	2
UniProt:O75182 SIN3B	1	SIN3B [nucleoplasm] (R-HSA-3006450)	0.527	2
UniProt:Q86YP4 GATAD2A	1	GATAD2A [nucleoplasm] (R-HSA-3702077)	0.527	2
UniProt:Q9NP50 SHCAF			0.527	2
UniProt:O43189 PHF1	1	PHF1 [nucleoplasm] (R-HSA-5084105)	0.527	2
UniProt:Q9UBB5 MBD2	1	MBD2 [nucleoplasm] (R-HSA-427367)	0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.527	3
UniProt:O75530 EED	1	EED [nucleoplasm] (R-HSA-212278)	0.527	3
UniProt:P62799 H4			0.524	2
UniProt:Q17R98 ZN827			0.499	2
UniProt:P12520 VPR			0.462	4
UniProt:Q8N5A5 ZGPAT			0.462	2
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.462	3

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