Reactome | TARS2(1-?) [mitochondrial matrix]

TARS2(1-?) [mitochondrial matrix]

Stable Identifier

R-HSA-379590

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

TARS2, Threonyl-tRNA synthetase 2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BW92 TARS2

Gene Names

TARS2, TARSL1

Chain

transit peptide:1-, chain:-718

Reference Genes

BioGPS Gene:80222 TARS2

COSMIC (genes):TARS2 TARS2

CTD Gene:80222 TARS2

dbSNP Gene:80222 TARS2

ENSEMBL:ENSG00000143374 TARS2

HGNC:30740 TARS2

Monarch:80222 TARS2

NCBI Gene:80222 TARS2

OMIM:612805 TARS2

UCSC:Q9BW92 TARS2

Reference Transcript

Other Identifiers

11726587_a_at

11747080_a_at

11752407_x_at

11753815_a_at

11753816_x_at

11753835_x_at

16670547

221189_PM_s_at

221189_s_at

2358321

2358322

2358323

2358324

2358325

2358326

2358327

2358328

2358329

2358330

2358331

2358332

2358333

2358334

2358335

2358339

2358340

2358341

2358343

2358344

2358345

2358346

2358347

2358348

2358349

2358350

2358351

2358352

2358353

2358354

2358356

2358357

2358358

2358361

2358362

2358363

3435889

70937_at

77221_s_at

77595_at

7895165

7905198

80222

A_14_P103598

A_14_P111509

A_23_P553

A_33_P3227275

GE83106

GO:0000166

GO:0002161

GO:0003824

GO:0004812

GO:0004829

GO:0005515

GO:0005524

GO:0005575

GO:0005737

GO:0005739

GO:0005759

GO:0006399

GO:0006412

GO:0006418

GO:0006435

GO:0006520

GO:0016787

GO:0016874

GO:0042802

GO:0042803

GO:0043039

GO:0043226

GO:0070159

GO:0106074

GO:0140098

HMNXSV003007541

HMNXSV003033889

HMNXSV003046106

ILMN_1778187

PH_hs_0015020

TC01001187.hg

g13376742_3p_a_at

Cross References

ENSEMBL

ENST00000369064, ENST00000369054, ENSP00000358060, ENSP00000358050

OpenTargets

ENSG00000143374

HPA

ENSG00000143374-TARS2

PRO

Q9BW92

Pharos - Targets

Q9BW92

GlyGen

Q9BW92

Orphanet

TARS2

HMDB Protein

HMDBP09249

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15041 AR6P1			0.556	3
UniProt:Q16563 SYPL1			0.556	3
UniProt:Q9NWX5 ASB6	1	ASB6 [cytosol] (R-HSA-975412)	0.556	3
UniProt:Q9BYT1 S17A9			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
IntAct:EBI-16436244 CCSB ORF ID			0.556	3
UniProt:Q969L2 MAL2			0.556	3
UniProt:O60664 PLIN3	7	p-PLIN3 [lysosomal lumen] (R-HSA-9639396) p-PLIN3 [cytosol] (R-HSA-9613664) p-PLIN3 [lipid droplet] (R-HSA-9613539) PLIN3 [lipid droplet] (R-HSA-9613337) p-PLIN3 [late endosome lumen] (R-HSA-9639393) PLIN3 [cytosol] (R-HSA-6814628) PLIN3 [transport vesicle] (R-HSA-6813900)	0.556	3
UniProt:A2RTX5 SYTC2			0.556	3
UniProt:Q9UBN6 TNFRSF10D	1	TNFRSF10D [plasma membrane] (R-HSA-5633374)	0.556	3
UniProt:Q9Y680 FKBP7			0.556	3
UniProt:Q8WV19 SFT2A			0.556	3
UniProt:Q9BYC2 OXCT2	1	OXCT2 [mitochondrial matrix] (R-HSA-8955625)	0.527	2
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	5

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