Reactome | ABLIM1 [cytosol]

ABLIM1 [cytosol]

Stable Identifier

R-HSA-416771

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Actin-binding LIM protein 1, ABLM1_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - Netrin-1 signaling (Homo sapiens)
      - DCC mediated attractive signaling (Homo sapiens)
        
        Recruitment of ABLIM to the plasma membrane (Homo sapiens)
        
        ABLIM [cytosol] (Homo sapiens)
        
        ABLIM1 [cytosol] (Homo sapiens)
        
        NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP:ABLIM [plasma membrane] (Homo sapiens)
        
        ABLIM [cytosol] (Homo sapiens)
        
        ABLIM1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:O14639 ABLIM1

Gene Names

ABLIM1, ABLIM, KIAA0059, LIMAB1

Chain

chain:1-778

Reference Genes

BioGPS Gene:3983 ABLIM1

COSMIC (genes):ABLIM1 ABLIM1

CTD Gene:3983 ABLIM1

dbSNP Gene:3983 ABLIM1

ENSEMBL:ENSG00000099204 ABLIM1

HGNC:78 ABLIM1

KEGG:hsa:3983 ABLIM1

Monarch:3983 ABLIM1

NCBI Gene:3983 ABLIM1

OMIM:602330 ABLIM1

UCSC:O14639 ABLIM1

Reference Transcript

Participates

as a member of

ABLIM [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_002304.3, NP_001003407.1, NP_001309821.1, NP_006711.3, NP_001309811.1, NP_001309822.1, NP_001309825.1

OpenTargets

ENSG00000099204

ENSEMBL

ENSP00000376679, ENST00000392952, ENSG00000099204, ENST00000533213, ENSP00000376682, ENST00000369256, ENSP00000358260, ENST00000392955, ENSP00000358257, ENSP00000433629, ENST00000369253

HPA

ENSG00000099204-ABLIM1

GeneCards

ABLIM1

PRO

O14639

Pharos - Targets

O14639

GlyGen

O14639

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.802	7
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.786	6
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.745	7
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.649	7
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.628	5
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) CARD9 [plasma membrane] (R-HSA-5607662) p-T231-CARD9 [plasma membrane] (R-HSA-5607623)	0.556	3

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