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TECR [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-548663
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Trans-2,3-enoyl-CoA reductase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Homo sapiens)
TECR,TECRL [endoplasmic reticulum membrane] (Homo sapiens)
TECR [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NZ01 TECR
Gene Names
TECR, GPSN2, SC2
Chain
chain:1-308
Reference Genes
BioGPS Gene:9524 TECR
COSMIC (genes):TECR TECR
CTD Gene:9524 TECR
dbSNP Gene:9524 TECR
ENSEMBL:ENSG00000099797 TECR
HGNC:4551 TECR
KEGG:hsa:9524 TECR
Monarch:9524 TECR
NCBI Gene:9524 TECR
OMIM:610057 TECR
UCSC:Q9NZ01 TECR
Reference Transcript
RefSeq:NM_001321170.1 TECR
RefSeq:NM_138501.5 TECR
Other Identifiers
11730198_s_at
11755502_x_at
1569392_PM_at
1569392_at
16859018
208336_PM_s_at
208336_s_at
2776902
2776903
2776904
2776905
2776906
2776907
2776908
2776909
3822806
3822811
3822812
3822813
3822814
3822815
3822816
3822818
3822819
3822820
3822822
3822823
3822824
3822825
3822827
3822828
3822829
3822830
3822831
3822832
3822833
3822834
3822835
3822836
3822837
3822838
3822839
3822840
3822841
3822842
3822843
3822844
3822845
3822846
3822847
3822848
38966_at
8026341
8101622
9524
A_14_P117499
A_14_P118805
A_23_P56339
A_33_P3372466
GE81450
GO:0003824
GO:0005515
GO:0005634
GO:0005783
GO:0005789
GO:0006629
GO:0006633
GO:0006665
GO:0006790
GO:0016020
GO:0016491
GO:0016627
GO:0017099
GO:0030497
GO:0035338
GO:0042761
GO:0043226
GO:0055086
GO:0102758
GO:1901135
HMNXSV003035748
Hs2.98153.1.S1_3p_at
ILMN_1671678
ILMN_1720799
PH_hs_0015721
PH_hs_0037993
TC04001361.hg
TC19000259.hg
TC19002003.hg
g4759061_3p_s_at
Participates
as a member of
TECR,TECRL [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
art-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
tecr [endoplasmic reticulum membrane]
(Xenopus tropicalis)
TECR [endoplasmic reticulum membrane]
(Bos taurus)
TECR [endoplasmic reticulum membrane]
(Canis familiaris)
TECR [endoplasmic reticulum membrane]
(Gallus gallus)
TECR [endoplasmic reticulum membrane]
(Plasmodium falciparum)
TECR [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
TECR [endoplasmic reticulum membrane]
(Sus scrofa)
Sc2 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
gpsn2 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Tecr [endoplasmic reticulum membrane]
(Mus musculus)
Tecr [endoplasmic reticulum membrane]
(Rattus norvegicus)
TSC13 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
Cross References
ENSEMBL
ENST00000215567
,
ENSP00000215567
OpenTargets
ENSG00000099797
HPA
ENSG00000099797-TECR
PRO
Q9NZ01
Pharos - Targets
Q9NZ01
GlyGen
Q9NZ01
Orphanet
TECR
HMDB Protein
HMDBP09218
PDB
2DZJ
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.615
18
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.569
3
UniProt:Q00059 TFAM
3
TFAM [mitochondrial matrix]
(R-HSA-163312)
TFAM(1-246) [cytosol]
(R-HSA-1592203)
p-S55,S56,S61,S160-TFAM [mitochondrial matrix]
(R-HSA-9838277)
0.556
3
UniProt:O00501 CLDN5
2
CLDN5 [cell junction]
(R-HSA-421264)
CLDN5 [plasma membrane]
(R-HSA-419991)
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
3
UniProt:Q8N4V1 MMGT1
1
MMGT1 [Golgi membrane]
(R-HSA-5216137)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:O15173 PGRMC2
4
PGRMC2 [nuclear envelope]
(R-HSA-9707674)
PGRMC2 [nucleoplasm]
(R-HSA-9707859)
PGRMC2 [endoplasmic reticulum membrane]
(R-HSA-9714349)
PGRMC2 [endosome membrane]
(R-HSA-9715090)
0.556
3
UniProt:Q86WV6 STING1
5
STING [endoplasmic reticulum membrane]
(R-HSA-1834940)
K63polyUb-STING [endoplasmic reticulum membrane]
(R-HSA-3134805)
K63polyUb-STING [cytoplasmic vesicle membrane]
(R-HSA-3248021)
TMEM173 [secretory granule membrane]
(R-HSA-6804798)
TMEM173 [plasma membrane]
(R-HSA-6804815)
0.556
3
UniProt:Q13418 ILK
1
ILK [cytosol]
(R-HSA-432864)
0.527
2
UniProt:P31152 MAPK4
4
MAPK4 [nucleoplasm]
(R-HSA-5686975)
MAPK4 [cytosol]
(R-HSA-5686973)
p-S186 MAPK4 [cytosol]
(R-HSA-5687023)
p-S186 MAPK4 [nucleoplasm]
(R-HSA-5687022)
0.527
2
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