Reactome | ADARB1 [nucleoplasm]

ADARB1 [nucleoplasm]

Stable Identifier

R-HSA-62915

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

ADAR2 protein, dsRNA adenosine deaminase, RNA editing enzyme 1, Double-stranded RNA-specific editase 1, Double-stranded RNA-specific editase 1 , RNA editing deaminase 1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P78563 ADARB1

Gene Names

ADARB1, ADAR2, DRADA2, RED1

Chain

chain:1-741

Reference Genes

BioGPS Gene:104 ADARB1

COSMIC (genes):ADARB1 ADARB1

CTD Gene:104 ADARB1

dbSNP Gene:104 ADARB1

ENSEMBL:ENSG00000197381 ADARB1

HGNC:226 ADARB1

KEGG:hsa:104 ADARB1

Monarch:104 ADARB1

NCBI Gene:104 ADARB1

OMIM:601218 ADARB1

UCSC:P78563 ADARB1

Reference Transcript

Participates

as a component of

ADAR2 homodimer [nucleoplasm] (Homo sapiens)

as an input of

Formation of ADAR2 homodimer (Homo sapiens)

Inferred To

adarb1 [nucleoplasm] (Xenopus tropicalis)

Adar [nucleoplasm] (Drosophila melanogaster)

adr-2 [nucleoplasm] (Caenorhabditis elegans)

Homologues of ADARB1 [nucleoplasm] (Xenopus tropicalis)

ADARB1 [nucleoplasm] (Bos taurus)

ADARB1 [nucleoplasm] (Canis familiaris)

ADARB1 [nucleoplasm] (Gallus gallus)

ADARB1 [nucleoplasm] (Sus scrofa)

Adarb1 [nucleoplasm] (Mus musculus)

Adarb1 [nucleoplasm] (Rattus norvegicus)

adarb1a [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_001103.1, XP_054180282.1, XP_054180281.1, XP_054180283.1, NP_001333616.1, XP_047296622.1, XP_016883738.1, XP_047296621.1, NP_001153702.1, XP_016883739.1, XP_047296623.1, NP_056648.1, NP_056649.1, XP_016883744.1, NP_001333617.1, XP_047296620.1, XP_016883737.1, XP_054180286.1, XP_054180285.1, XP_016883736.1, XP_016883740.1, XP_016883743.1

OpenTargets

ENSG00000197381

ENSEMBL

ENSG00000197381, ENST00000496664, ENSP00000015877, ENSP00000435381, ENST00000449478, ENST00000492414, ENST00000348831, ENSP00000516121, ENSP00000387480, ENST00000389861, ENST00000389863, ENSP00000353920, ENSP00000374513, ENST00000360697, ENSP00000436367

HPA

ENSG00000197381-ADARB1

GeneCards

ADARB1

PRO

P78563

Pharos - Targets

P78563

PDB

7KFN, 5ED1, 6D06, 5HP2, 8E4X, 9D5K, 8E0F, 6VFF, 9D5J, 5ED2, 5HP3, 1ZY7

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC9 N	13	SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729340) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9729341) ADPr-p-11S,2T-metR95,177-N [cytosol] (R-COV-9729275) p-11S,2T-metR95,177-N [cytosol] (R-COV-9729308) p-11S,2T-N [cytosol] (R-COV-9729264) p-8S,2T-N [cytosol] (R-COV-9729277) p-8S-N [cytosol] (R-COV-9729335) p-S188,206-N [cytosol] (R-COV-9729324) N [cytosol] (R-COV-9694300) SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol] (R-COV-9756489) N [plasma membrane] (R-COV-9694356) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus] (R-COV-9729339) SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane] (R-COV-9729325)	0.601	4
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.571	12
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.556	3
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.556	3
UniProt:O75569 PRKRA	2	p-S246,S287-PRKRA [cytosol] (R-HSA-9834791) PRKRA [cytosol] (R-HSA-2399897)	0.547	2
UniProt:O76021 RL1D1			0.547	2
UniProt:O75683 SURF6			0.547	2
UniProt:Q9H116 GZF1			0.527	2
UniProt:Q9H7E9 CH033			0.527	2
UniProt:Q6PK04 CC137			0.527	2
UniProt:Q9BRD0 BUD13	1	BUD13 [nucleoplasm] (R-HSA-9769522)	0.527	2
UniProt:Q68D10 SPT2			0.527	2

Cite Us!