Reactome | LONRF1 [cytosol]

LONRF1 [cytosol]

Stable Identifier

R-HSA-8850905

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

LON peptidase N-terminal domain and RING finger protein 1, LONF1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q17RB8 LONRF1

Gene Names

LONRF1, RNF191

Chain

chain:1-773

Reference Genes

BioGPS Gene:91694 LONRF1

COSMIC (genes):LONRF1 LONRF1

CTD Gene:91694 LONRF1

dbSNP Gene:91694 LONRF1

ENSEMBL:ENSG00000154359 LONRF1

ENSEMBL_homo_sapiens_GENE:ENSG00000154359.13 LONRF1

HGNC:26302 LONRF1

KEGG Gene (Homo sapiens):91694 LONRF1

Monarch:91694 LONRF1

NCBI Gene:91694 LONRF1

UCSC:Q17RB8 LONRF1

Reference Transcript

Other Identifiers

11731076_a_at

11731077_a_at

11757558_s_at

17074815

226038_PM_at

226038_at

3125005

3125006

3125010

3125013

3125014

3125015

3125018

3125020

3125022

3125023

3125024

3125025

3125026

3125027

3125028

3125029

3125030

3125031

3125032

3125038

3125039

3125040

3125041

3125042

3125043

3125044

3125045

54826_at

8149399

91694

A_23_P94216

A_24_P406480

A_24_P934202

A_32_P194032

GE79015

GO:0003824

GO:0005515

GO:0005737

GO:0005829

GO:0016740

GO:0046872

GO:0061630

GO:0140096

HMNXSV003003529

Hs.180178.0.S1_3p_at

ILMN_1705953

PH_hs_0010665

TC08000997.hg

Participates

as a member of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

lonrf1 [cytosol] (Danio rerio)

Lonrf1 [cytosol] (Mus musculus)

Lonrf1 [cytosol] (Rattus norvegicus)

CG7388 [cytosol] (Drosophila melanogaster)

LONRF1 [cytosol] (Bos taurus)

LONRF1 [cytosol] (Canis familiaris)

LONRF1 [cytosol] (Gallus gallus)

LONRF1 [cytosol] (Plasmodium falciparum)

LONRF1 [cytosol] (Schizosaccharomyces pombe)

LONRF1 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_689484.3, NP_001316905.1

OpenTargets

ENSG00000154359

HPA

ENSG00000154359-LONRF1

GeneCards

Q17RB8

Ensembl

ENSG00000154359, ENST00000398246, ENSP00000381298

PRO

Q17RB8

Pharos - Targets

Q17RB8

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14933 UBE2L6	2	UBE2L6 [cytosol] (R-HSA-936014) UBE2L6 [nucleoplasm] (R-HSA-5653666)	0.781	7
UniProt:P98170 XIAP	3	XIAP [nucleoplasm] (R-HSA-3322366) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [cytosol] (R-HSA-50849)	0.781	7
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.718	6
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.718	8
UniProt:Q7Z3C6 ATG9A	1	ATG9A [phagophore assembly site membrane] (R-HSA-5671732)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [nucleoplasm] (R-HSA-174333) PSMA1 [cytosol] (R-HSA-68724)	0.556	3
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:P50458 LHX2	1	LHX2 [nucleoplasm] (R-HSA-9011100)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.556	3
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.556	3
UniProt:O43597 SPRY2	8	p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55-SPRY2 [cytosol] (R-HSA-182950) SPRY2 [plasma membrane] (R-HSA-182924) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595)	0.556	3
UniProt:O95391 SLU7	1	hSLU7 [nucleoplasm] (R-HSA-72073)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q06710 PAX8	1	PAX8 [nucleoplasm] (R-HSA-3968418)	0.556	3
UniProt:P22736 NR4A1	2	p-S351-NR4A1 [nucleoplasm] (R-HSA-199846) NR4A1 [nucleoplasm] (R-HSA-199831)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.556	3
UniProt:Q9UQK1 PPP1R3C	2	K48polyUb-PPP1R3C [cytosol] (R-HSA-3781005) PPP1R3C [cytosol] (R-HSA-3777102)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3

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