Reactome | RNF182 [cytosol]

RNF182 [cytosol]

Stable Identifier

R-HSA-976010

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase RNF182, RN182_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N6D2 RNF182

Gene Names

RNF182

Chain

chain:1-247

Reference Genes

BioGPS Gene:221687 RNF182

COSMIC (genes):RNF182 RNF182

CTD Gene:221687 RNF182

dbSNP Gene:221687 RNF182

ENSEMBL:ENSG00000180537 RNF182

ENSEMBL_homo_sapiens_GENE:ENSG00000180537.13 RNF182

HGNC:28522 RNF182

KEGG Gene (Homo sapiens):221687 RNF182

Monarch:221687 RNF182

NCBI Gene:221687 RNF182

UCSC:Q8N6D2 RNF182

Reference Transcript

Other Identifiers

11737774_a_at

17004989

221687

230720_PM_at

230720_at

2895809

2895810

2895814

2895815

2895816

2895817

2895818

2895819

2895820

2895821

60254_at

8116980

A_14_P200162

A_23_P399255

GE504066

GO:0003824

GO:0004842

GO:0005515

GO:0005737

GO:0016020

GO:0016567

GO:0016740

GO:0036211

GO:0046872

GO:0140096

HMNXSV003017931

Hs.111164.0.A1_3p_at

PH_hs_0006106

TC06000097.hg

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

rnf182 [cytosol] (Xenopus tropicalis)

RNF182 [cytosol] (Bos taurus)

RNF182 [cytosol] (Canis familiaris)

RNF182 [cytosol] (Danio rerio)

RNF182 [cytosol] (Gallus gallus)

RNF182 [cytosol] (Sus scrofa)

Rnf182 [cytosol] (Mus musculus)

Rnf182 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

XP_016865937.1, XP_016865938.1, NP_001158505.1, NP_001158504.1, NP_001158506.1, NP_689950.1, XP_016865939.1

OpenTargets

ENSG00000180537

IntEnz

2.3.2.27

HPA

ENSG00000180537-RNF182

GeneCards

Q8N6D2

Ensembl

ENSP00000443228, ENST00000488300, ENST00000544682, ENSP00000420465, ENSP00000442021, ENSP00000441271, ENST00000537388, ENST00000537663, ENSG00000180537

PRO

Q8N6D2

Pharos - Targets

Q8N6D2

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61088 UBE2N	5	Ub-C87-UBE2N [nucleoplasm] (R-HSA-8943013) Ub-C87-UBE2N [cytosol] (R-HSA-8864210) K63polyUb-C87-UBE2N [nucleoplasm] (R-HSA-6790511) UBE2N [nucleoplasm] (R-HSA-5682541) UBE2N [cytosol] (R-HSA-206072)	0.592	2
UniProt:P51668 UBE2D1	3	UBE2D1 [cytosol] (R-HSA-174236) UBE2D1 [nucleoplasm] (R-HSA-174197) Ub-C85-UBE2D1 [cytosol] (R-HSA-8864160)	0.556	3
UniProt:P68036 UBE2L3	4	Ub-C86-UBE2L3 [nucleoplasm] (R-HSA-8864226) UBE2L3 [nucleoplasm] (R-HSA-8852056) Ub-C86-UBE2L3 [cytosol] (R-HSA-8864201) UBE2L3 [cytosol] (R-HSA-947631)	0.556	3