Reactome | SPATA2 [cytosol]

SPATA2 [cytosol]

Stable Identifier

R-HSA-9796351

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Spermatogenesis-associated protein 2, KIAA0757, PD1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UM82 SPATA2

Gene Names

SPATA2, KIAA0757, PD1

Chain

chain:1-520

Reference Genes

BioGPS Gene:9825 SPATA2

COSMIC (genes):SPATA2 SPATA2

CTD Gene:9825 SPATA2

dbSNP Gene:9825 SPATA2

ENSEMBL:ENSG00000158480 SPATA2

ENSEMBL_homo_sapiens_GENE:ENSG00000158480.11 SPATA2

HGNC:14681 SPATA2

KEGG Gene (Homo sapiens):9825 SPATA2

Monarch:9825 SPATA2

NCBI Gene:9825 SPATA2

OMIM:607662 SPATA2

UCSC:Q9UM82 SPATA2

Reference Transcript

Other Identifiers

11725591_a_at

11725592_a_at

11725593_s_at

11725594_x_at

11727024_a_at

11751072_a_at

11758471_s_at

16920180

204433_PM_s_at

204433_s_at

204434_PM_at

204434_at

36050_at

3909036

3909037

3909038

3909039

3909040

3909041

3909042

3909043

3909044

3909046

3909047

8066953

9825

A_23_P210554

A_24_P164838

GE53466

GO:0001650

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0006954

GO:0007283

GO:0010803

GO:0012501

GO:0022414

GO:0023052

GO:0030159

GO:0036211

GO:0043226

GO:0044877

GO:0048856

GO:0050727

GO:0060090

GO:0060544

GO:0070266

GO:0070536

GO:0072520

GO:1990108

GO:1990381

HMNXSV003045891

ILMN_1681135

PH_hs_0028894

TC20000929.hg

g4730926_3p_a_at

g5174486_3p_at

Participates

as an input of

SPATA2 links CYLD to LUBAC (Homo sapiens)

as a component of

CYLD:SPATA2:LUBAC [cytosol] (Homo sapiens)

Inferred To

Spata2 [cytosol] (Mus musculus)

Spata2 [cytosol] (Rattus norvegicus)

SPATA2 [cytosol] (Bos taurus)

SPATA2 [cytosol] (Canis familiaris)

SPATA2 [cytosol] (Gallus gallus)

SPATA2 [cytosol] (Sus scrofa)

tamo [cytosol] (Drosophila melanogaster)

spata2 [cytosol] (Danio rerio)

spata2 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001129245.1, XP_006723957.1, NP_006029.1, XP_011527418.1

OpenTargets

ENSG00000158480

HPA

ENSG00000158480-SPATA2

GeneCards

Q9UM82

Ensembl

ENSG00000158480, ENST00000422556, ENSP00000416799, ENST00000289431, ENSP00000289431

PRO

Q9UM82

Pharos - Targets

Q9UM82

Orphanet

24941

PDB

5LJM, 5LJN

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.666	4
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.666	4
UniProt:Q9NQC7 CYLD	3	p-S418-CYLD [cytosol] (R-HSA-5212667) K48polyUb-K338, K530-CYLD [cytosol] (R-HSA-9818664) CYLD [cytosol] (R-HSA-741420)	0.589	3
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q9NU19 TB22B			0.556	3
UniProt:Q5JVL4 EFHC1			0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q9UI12 ATP6V1H	2	ATP6V1H [cytosol] (R-HSA-167578) ATP6V1H [plasma membrane] (R-HSA-167602)	0.556	3
UniProt:Q53TS8 CTSRT			0.556	3
UniProt:Q15025 TNIP1	1	TNIP1 [cytosol] (R-HSA-5690853)	0.556	3
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
UniProt:X5D778 X5D778			0.556	3
UniProt:Q9Y2P0 ZN835			0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:O95872 GPAN1			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.553	2
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	2