Reactome | SMARCA4 [nucleoplasm]

SMARCA4 [nucleoplasm]

Stable Identifier

R-MMU-201686

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Q3TKT4

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional regulation by RUNX1 (Mus musculus)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Mus musculus)
        
        RUNX1 binds the SWI/SNF complex (Mus musculus)
        
        RUNX1:CBFB:SWI/SNF [nucleoplasm] (Mus musculus)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Mus musculus)
        
        SMARCA2,SMARCA4:SMARCB1:SMARCC1:SMARCC2 [nucleoplasm] (Mus musculus)
        
        SMARCA2,SMARCA4 [nucleoplasm] (Mus musculus)
        
        SMARCA4 [nucleoplasm] (Mus musculus)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Mus musculus)
        
        SMARCA2,SMARCA4:SMARCB1:SMARCC1:SMARCC2 [nucleoplasm] (Mus musculus)
        
        SMARCA2,SMARCA4 [nucleoplasm] (Mus musculus)
        
        SMARCA4 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q3TKT4

Reference Genes

BioGPS Gene:20586

ENSEMBL:ENSMUSG00000032187

KEGG Gene (Mus musculus):20586

Monarch:20586

NCBI Gene:20586

UCSC:Q3TKT4

Reference Transcript

Other Identifiers

10583697

1426804_at

1426805_at

17515277

20586

4418154

4479444

4486263

4504250

4506043

4524150

4622183

4623440

4630553

4640431

4661043

4680263

4685631

4729737

4748306

4833454

4943291

5057667

5057902

5077732

5099828

5127299

5212243

5218813

5232224

5253853

5277518

5303401

5309719

5326636

5335857

5379699

5383396

5384703

5408223

5425667

5479386

5500162

5539418

5575265

5598973

98463_at

A_51_P331702

A_51_P479733

A_52_P147044

A_55_P2154684

A_55_P2154690

A_65_P20042

GE1491980

GE1547270

GO:0000122

GO:0000166

GO:0000228

GO:0000278

GO:0000776

GO:0000785

GO:0000791

GO:0000792

GO:0000902

GO:0000977

GO:0000978

GO:0001164

GO:0001188

GO:0001221

GO:0001568

GO:0001570

GO:0001650

GO:0001673

GO:0001701

GO:0001832

GO:0001835

GO:0001889

GO:0002039

GO:0002376

GO:0003151

GO:0003281

GO:0003677

GO:0003682

GO:0003713

GO:0003714

GO:0003723

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005694

GO:0005726

GO:0005730

GO:0006281

GO:0006325

GO:0006334

GO:0006337

GO:0006338

GO:0006346

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0007059

GO:0007155

GO:0007399

GO:0007403

GO:0007507

GO:0008094

GO:0008284

GO:0010424

GO:0010467

GO:0012501

GO:0016363

GO:0016514

GO:0016586

GO:0016787

GO:0016887

GO:0019827

GO:0022008

GO:0023052

GO:0030071

GO:0030154

GO:0030177

GO:0030198

GO:0030216

GO:0030308

GO:0030334

GO:0030900

GO:0030902

GO:0030957

GO:0035116

GO:0035887

GO:0035904

GO:0036211

GO:0042393

GO:0043066

GO:0043226

GO:0043388

GO:0043923

GO:0043966

GO:0044877

GO:0045582

GO:0045596

GO:0045597

GO:0045663

GO:0045815

GO:0045892

GO:0045893

GO:0045944

GO:0048562

GO:0048730

GO:0048856

GO:0048870

GO:0050681

GO:0051091

GO:0060318

GO:0060319

GO:0060347

GO:0060766

GO:0060976

GO:0061626

GO:0065003

GO:0070182

GO:0070307

GO:0070316

GO:0070577

GO:0070603

GO:0071564

GO:0071565

GO:0106222

GO:0120162

GO:0140014

GO:0140092

GO:0140097

GO:0140110

GO:0140288

GO:0140657

GO:0140658

GO:1901838

GO:1902459

GO:1902661

GO:1902895

GO:2000045

GO:2000781

GO:2000819

ILMN_2735792

Msa.14584.0_s_at

Msa.18914.0_s_at

Msa.30464.0_s_at

Msa.9908.0_f_at

S68108_s_at

mMC001058

Participates

as an input of

as a component of

as a member of

SMARCA2,SMARCA4 [nucleoplasm] (Mus musculus)

Inferred From

SMARCA4 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_006510182.2, NP_001167550.1, NP_035547.2, XP_006510180.2, NP_001167549.1, XP_006510183.2

Ensembl

ENSMUSP00000133922, ENSMUST00000174008, ENSMUSP00000034707, ENSMUSG00000032187, ENSMUST00000034707

PRO

Q3TKT4

MGI

88192

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P97496	1	Smarcc1 [nucleoplasm] (R-MMU-389257)	0.769	7
UniProt:A2BH40	1	Arid1a [nucleoplasm] (R-MMU-389259)	0.662	7
UniProt:O54941	1	Smarce1 [nucleoplasm] (R-MMU-389258)	0.643	5
UniProt:E9Q4N7	1	Arid1b [nucleoplasm] (R-MMU-5225635)	0.623	5
UniProt:Q62908 CSRP2			0.591	3
UniProt:Q6P9Z1	1	Smarcd3 [nucleoplasm] (R-MMU-400141)	0.576	3
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.573	4
UniProt:Q9Z2D6 Mecp2			0.564	2
UniProt:Q62280 SSXT			0.527	4
UniProt:Q9Z0H3	1	Smarcb1 [nucleoplasm] (R-MMU-389261)	0.527	4
UniProt:P20263 Pou5f1	2	Pou5f1 [nucleoplasm] (R-MMU-3245981) POU5F1 [nucleoplasm] (R-MMU-452472)	0.527	3
UniProt:O70372	1	TERT [nucleoplasm] (R-MMU-163076)	0.524	2
UniProt:Q8VEK3	1	HNRNPU [nucleoplasm] (R-MMU-71953)	0.518	3
UniProt:P13405 Rb1	18	Rb1 [nucleoplasm] (R-MMU-68642) phospho-Rb1 [nucleoplasm] (R-MMU-9687347) phospho-Rb1 [nucleoplasm] (R-MMU-9687351) phospho-Rb1 [nucleoplasm] (R-MMU-9687355) phospho-Rb1 [nucleoplasm] (R-MMU-9687354) phospho-Rb1 [nucleoplasm] (R-MMU-9687353) phospho-Rb1 [nucleoplasm] (R-MMU-9687352) phospho-Rb1 [nucleoplasm] (R-MMU-69226) phospho-Rb1 [nucleoplasm] (R-MMU-9687357) phospho-Rb1 [nucleoplasm] (R-MMU-9687356) phospho-Rb1 [nucleoplasm] (R-MMU-9687335) phospho-Rb1 [nucleoplasm] (R-MMU-9687334) phospho-Rb1 [nucleoplasm] (R-MMU-9687339) phospho-Rb1 [nucleoplasm] (R-MMU-9687336) phospho-Rb1 [nucleoplasm] (R-MMU-9687343) Rb1 [cytosol] (R-MMU-9660621) phospho-Rb1 [nucleoplasm] (R-MMU-188389) Rb1 [nucleoplasm] (R-MMU-1227910)	0.508	3
UniProt:Q99N13 HDAC9			0.499	3
UniProt:P70288 Hdac2	2	Hdac2 [nucleoplasm] (R-MMU-4615958) Hdac2 [nucleoplasm] (R-MMU-573366)	0.499	4
UniProt:P11103	4	polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-MMU-4551617) monoSUMO1-K203,K486-PARP1 [nucleoplasm] (R-MMU-4551686) PAR-PARP1 [nucleoplasm] (R-MMU-5651713) PARP1 [nucleoplasm] (R-MMU-201568)	0.499	2
UniProt:Q01320 Top2a	5	monoSumo1-Top2a [nucleoplasm] (R-MMU-5228510) Top2a [nucleoplasm] (R-MMU-5228506) monoSUMO1-K-TOP2A [nucleoplasm] (R-MMU-4641367) polySUMO2,3-TOP2A [nucleoplasm] (R-MMU-4641298) TOP2A [nucleoplasm] (R-MMU-1362276)	0.499	3
UniProt:Q8CIG8	3	phospho-p-Y297,304,307-PRMT5 [nucleoplasm] (R-MMU-5211300) PRMT5 [nucleoplasm] (R-MMU-5205609) PRMT5 [cytosol] (R-MMU-191876)	0.499	2
UniProt:Q01705 Notch1	20	Notch1 [endosome membrane] (R-MMU-9793910) p-NICD1 [nucleoplasm] (R-MMU-2064842) NICD1 [cytosol] (R-MMU-205738) N1' [plasma membrane] (R-MMU-206107) NTM' [extracellular region] (R-MMU-206219) NEXT1 [plasma membrane] (R-MMU-205889) NdeltaE [plasma membrane] (R-MMU-2063913) Fringe-modified NECD1 [plasma membrane] (R-MMU-2053928) Glc,GlcNAc-Fuc-Pre-Notch1 [Golgi membrane] (R-MMU-2023154) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane] (R-MMU-1911503) FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [Golgi membrane] (R-MMU-1911511) NTM [plasma membrane] (R-MMU-206117) Notch1 Extracellular Domain (NECD1) [extracellular region] (R-MMU-2032285) Glc,Fuc-Pre-Notch1 [Golgi membrane] (R-MMU-2023160) Glc,Fuc-Pre-Notch1 [endoplasmic reticulum membrane] (R-MMU-2023167) Fuc-Pre-Notch1 [endoplasmic reticulum membrane] (R-MMU-1985704) Pre-Notch1 [endoplasmic reticulum membrane] (R-MMU-1984030) nicd1 [nucleoplasm] (R-MMU-189582) 17xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [Golgi membrane] (R-MMU-1472872) NOTCH1(1665-2555) [Golgi membrane] (R-MMU-157092)	0.499	2