Reactome | Dok2 [cytosol]

Dok2 [cytosol]

Stable Identifier

R-MMU-204823

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

DOK2, O70469

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O70469

Gene Names

Dok2

Reference Genes

BioGPS Gene:13449 Dok2

ENSEMBL:ENSMUSG00000022102

KEGG:mmu:13449 Dok2

Monarch:13449 Dok2

NCBI Gene:13449 Dok2

UCSC:O70469 Dok2

Reference Transcript

RefSeq:NM_010071.2 Dok2

Other Identifiers

102334_at

10416334

13449

1416333_at

17301802

4325934

4327326

4439473

4503584

4509353

4702090

4807368

4863525

4896367

4926567

4939752

4954626

5090494

5090998

5091960

5163368

5326003

5407135

5543234

5612064

A_51_P446469

A_66_P110829

GO:0005068

GO:0005515

GO:0005737

GO:0007169

GO:0007265

GO:0043409

GO:0043410

GO:0060090

ILMN_3160659

mMC024314

Participates

as a member of

DOK1,DOK2,DOK4,DOK5,DOK6 [cytosol] (Mus musculus)

as an input of

Interaction of Tie2 and Dok-2 (Mus musculus)

as a component of

Tie2 and Dok-2 complex [plasma membrane] (Mus musculus)

Inferred From

DOK2 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSMUST00000022698, ENSMUSP00000022698

PRO

O70469

MGI

1332623

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q91YX7 Q91YX7			0.641	4
UniProt:O55033 Nck2	2	Nck2 [cytosol] (R-MMU-8985827) Nck2 [cytosol] (R-MMU-204885)	0.564	2
UniProt:P41241	2	CSK [plasma membrane] (R-MMU-180499) CSK [cytosol] (R-MMU-203776)	0.524	2
UniProt:P05480 Src	13	SRC-2 [cytosol] (R-MMU-191648) phospho-MyrG-p-Y419-SRC [plasma membrane] (R-MMU-1810408) SRC-1 [plasma membrane] (R-MMU-65043) phospho-MyrG,p-Y530-SRC [plasma membrane] (R-MMU-377598) phospho-p-Y419-SRC [cytosol] (R-MMU-377592) Src [cytosol] (R-MMU-418782) phospho-p-Y419-SRC-1 [plasma membrane] (R-MMU-112331) MyrG-SRC [plasma membrane] (R-MMU-8876922) phospho-p-Y419-SRC [cytosol] (R-MMU-8964276) SRC [cytosol] (R-MMU-9628701) MyrG-p-Y424-Src [plasma membrane] (R-MMU-9011258) Activated Src [nucleoplasm] (R-MMU-8937700) p-Y416-Src [cytosol] (R-MMU-8964306)	0.524	3
UniProt:P00520 Abl1	7	phospho-p-S456-ABL1 [nucleoplasm] (R-MMU-5686576) ABL1 [nucleoplasm] (R-MMU-5686579) p-Y226,Y393-ABL1 [cytosol] (R-MMU-8942610) ABL1 [cytosol] (R-MMU-375987) p-Y226,Y393-ABL1 [nucleoplasm] (R-MMU-8985251) phospho-p-Y393-ABL1 [cytosol] (R-MMU-9865161) Abl1 [cytosol] (R-MMU-449189)	0.524	5

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