Reactome | ATP5PO [mitochondrial inner membrane]

ATP5PO [mitochondrial inner membrane]

Stable Identifier

R-HSA-164533

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

OSCP, ATP5O, ATP synthase oligomycin sensitivity conferral protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P48047 ATP5PO

Gene Names

ATP5PO, ATP5O, ATPO

Chain

transit peptide:1-23, chain:24-213

Reference Genes

BioGPS Gene:539 ATP5PO

COSMIC (genes):ATP5PO ATP5PO

CTD Gene:539 ATP5PO

dbSNP Gene:539 ATP5PO

ENSEMBL:ENSG00000241837 ATP5O

HGNC:850 ATP5PO

KEGG:hsa:539 ATP5PO

Monarch:539 ATP5PO

NCBI Gene:539 ATP5PO

OMIM:600828 ATP5PO

UCSC:P48047 ATP5PO

Reference Transcript

RefSeq:NM_001697.2 ATP5PO

Other Identifiers

11720328_a_at

11755346_x_at

11757727_x_at

16925293

200818_PM_at

200818_at

37029_at

3929934

3929935

3929938

3929941

3929942

3929943

3929944

3929945

3929946

3929948

3929950

3929951

3929952

3929953

3929954

3929955

3929956

3929957

3929958

539

8070160

A_23_P143474

GE78950

GO:0003824

GO:0005215

GO:0005515

GO:0005634

GO:0005739

GO:0005743

GO:0005886

GO:0006754

GO:0015986

GO:0016020

GO:0016874

GO:0042776

GO:0043226

GO:0045259

GO:0045265

GO:0046933

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003036129

ILMN_1791332

PH_hs_0024783

PH_hs_0033202

TC21000938.hg

TC21001056.hg

X83218_at

g4502302_3p_at

g4502302_3p_s_at

Participates

as a member of

Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ATP5 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

atp5po [mitochondrial inner membrane] (Danio rerio)

atp5po [mitochondrial inner membrane] (Dictyostelium discoideum)

atp5 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

Atp5po [mitochondrial inner membrane] (Mus musculus)

Atp5po [mitochondrial inner membrane] (Rattus norvegicus)

atp-3 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP5PO [mitochondrial inner membrane] (Bos taurus)

ATP5PO [mitochondrial inner membrane] (Canis familiaris)

ATP5PO [mitochondrial inner membrane] (Gallus gallus)

ATP5PO [mitochondrial inner membrane] (Sus scrofa)

ATPsynO [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000290299, ENST00000290299

OpenTargets

ENSG00000241837

HPA

ENSG00000241837-ATP5PO

PRO

P48047

Pharos - Targets

P48047

GlyGen

P48047

HMDB Protein

HMDBP01275

PDB

8H9V, 8H9P, 8H9U, 8H9E, 8H9T, 8H9S, 8H9L, 8H9I, 8KI3

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	6
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.527	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3
UniProt:P51451 BLK	2	MyrG2-BLK [plasma membrane] (R-HSA-9606871) BLK [cytosol] (R-HSA-983580)	0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	9
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2

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