Reactome | TAB3 [endosome membrane]

TAB3 [endosome membrane]

Stable Identifier

R-HSA-450247

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Mitogen-activated protein kinase kinase kinase 7-interacting protein 3

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8N5C8 TAB3

Gene Names

TAB3, MAP3K7IP3

Chain

initiator methionine:, chain:2-712

Reference Genes

BioGPS Gene:257397 TAB3

COSMIC (genes):TAB3 TAB3

CTD Gene:257397 TAB3

dbSNP Gene:257397 TAB3

ENSEMBL:ENSG00000157625 TAB3

HGNC:30681 TAB3

KEGG:hsa:257397 TAB3

Monarch:257397 TAB3

NCBI Gene:257397 TAB3

OMIM:300480 TAB3

UCSC:Q8N5C8 TAB3

Reference Transcript

Other Identifiers

11741815_a_at

11741816_s_at

11746378_a_at

11746379_a_at

11752679_a_at

1552927_PM_at

1552927_at

1552928_PM_s_at

1552928_s_at

1558518_PM_at

1558518_at

17109901

227357_PM_at

227357_at

257397

4003961

4003962

4003963

4003964

4003965

4003966

4003967

4003968

4003969

4003970

4003971

4003972

4003973

4003975

4003976

4003977

4003978

4003979

4003980

4003983

4003984

4003985

4003986

4003987

4003988

4003989

4003990

4003992

4003993

4003994

4003996

4003998

4004010

47843_at

76839_at

8171901

88365_at

A_23_P305033

A_32_P162150

A_33_P3251347

GE562106

GE87145

GO:0005515

GO:0005783

GO:0005829

GO:0005886

GO:0008270

GO:0010008

GO:0010507

GO:0038061

GO:0042742

GO:0043123

GO:0043130

GO:0043226

GO:0046872

GO:0060090

GO:0070062

GO:0070530

GO:0098542

HMNXSV003011075

HMNXSV003023596

HMNXSV003039976

Hs.135055.0.A1_3p_at

Hs2.365565.1.S1_3p_s_at

Hs2.365565.2.S1_3p_x_at

ILMN_1671351

ILMN_1748272

PH_hs_0017470

PH_hs_0029904

PH_hs_0039191

TC0X000941.hg

Participates

as a member of

TAB2/3 [endosome membrane] (Homo sapiens)

Other forms of this molecule

TAB3 [plasma membrane]

TAB3 [cytosol]

Inferred To

Tab3 [endosome membrane] (Mus musculus)

Tab3 [endosome membrane] (Rattus norvegicus)

tab3 [endosome membrane] (Xenopus tropicalis)

TAB3 [endosome membrane] (Bos taurus)

TAB3 [endosome membrane] (Canis familiaris)

TAB3 [endosome membrane] (Gallus gallus)

TAB3 [endosome membrane] (Sus scrofa)

Cross References

RefSeq

XP_005274540.2, NP_690000.3

ENSEMBL

ENST00000378932, ENST00000288422, ENST00000378933, ENSP00000368212, ENSP00000368214, ENSP00000368215, ENSP00000288422, ENST00000378930

OpenTargets

ENSG00000157625

HPA

ENSG00000157625-TAB3

PRO

Q8N5C8

Pharos - Targets

Q8N5C8

GlyGen

Q8N5C8

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43318 MAP3K7	10	PolyUb-MAP3K7 [cytosol] (R-HSA-6782968) MAP3K7 [plasma membrane] (R-HSA-9012677) p-T187-MAP3K7 [cytosol] (R-HSA-206014) K63polyUb-34,158-TAK1 [cytosol] (R-HSA-5607643) K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] (R-HSA-5607649) p-MAP3K7 [cytosol] (R-HSA-168163) MAP3K7 [endosome membrane] (R-HSA-450315) p-T184,T187-MAP3K7 [endosome membrane] (R-HSA-450332) MAP3K7 [cytosol] (R-HSA-168156) p-T184,T187-MAP3K7 [cytosol] (R-HSA-202527)	0.773	5
UniProt:Q14457 BECN1	4	BECN1 [cytosol] (R-HSA-1632841) p-S15-BECN1 [cytosol] (R-HSA-5682391) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) K63polyUb-BECN1 [cytosol] (R-HSA-6782989)	0.655	9
UniProt:Q15750 TAB1	6	TAB1 [cytosol] (R-HSA-167923) TAB1 [endosome membrane] (R-HSA-450238) TAB1(1-444) [cytosol] (R-HSA-9729751) TAB1(1-132) [cytosol] (R-HSA-9729698) TAB1(133-504) [cytosol] (R-HSA-9729724) TAB1(445-504) [cytosol] (R-HSA-9729691)	0.643	5
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3