Reactome | MRPL21 [mitochondrial inner membrane]

MRPL21 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368231

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

39S ribosomal protein L21, mitochondrial, RM21_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q7Z2W9 MRPL21

Gene Names

MRPL21

Chain

transit peptide:1-39, chain:40-205

Reference Genes

BioGPS Gene:219927 MRPL21

COSMIC - genes:MRPL21 MRPL21

CTD Gene:219927 MRPL21

dbSNP Gene:219927 MRPL21

ENSEMBL:ENSG00000197345 MRPL21

HGNC:14479 MRPL21

KEGG:hsa:219927 MRPL21

Monarch:219927 MRPL21

NCBI Gene:219927 MRPL21

OMIM:611834 MRPL21

UCSC:Q7Z2W9 MRPL21

Reference Transcript

Other Identifiers

11719482_a_at

16741314

219927

225315_PM_at

225315_at

2593628

3379714

3379715

3379716

3379717

3379718

3379719

3379720

3379721

3379722

3379723

3379724

3379725

3379726

3379727

3379728

3379729

3379733

3379734

3379735

44059_at

74792_at

7949995

A_23_P115955

GE87260

GO:0003723

GO:0003735

GO:0005198

GO:0005737

GO:0005739

GO:0005743

GO:0005762

GO:0005840

GO:0006412

GO:0032543

GO:1990904

HMNXSV003002568

HMNXSV003054903

Hs.286.2.A1_3p_at

ILMN_1654250

ILMN_1744835

ILMN_2348050

PH_hs_0018483

TC11002011.hg

TC11003226.hg

Participates

as a component of

39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

MRPL21 [mitochondrial inner membrane] (Bos taurus)

MRPL21 [mitochondrial inner membrane] (Gallus gallus)

MRPL21 [mitochondrial inner membrane] (Sus scrofa)

mRpL21 [mitochondrial inner membrane] (Drosophila melanogaster)

mrpl21 [mitochondrial inner membrane] (Danio rerio)

mrpl21 [mitochondrial inner membrane] (Xenopus tropicalis)

LOC119868876 [mitochondrial inner membrane] (Canis familiaris)

mrpl-21 [mitochondrial inner membrane] (Caenorhabditis elegans)

Mrpl21 [mitochondrial inner membrane] (Mus musculus)

Mrpl21 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_852616.1, NP_852615.1

OpenTargets

ENSG00000197345

ENSEMBL

ENSG00000197345, ENST00000450904, ENST00000362034, ENSP00000389400, ENSP00000354580

HPA

ENSG00000197345-MRPL21

GeneCards

MRPL21

PRO

Q7Z2W9

Pharos - Targets

Q7Z2W9

PDB

6VLZ, 6ZM6, 7A5I, 8XT2, 7A5J, 7OIA, 7OIC, 7OI8, 7OI7, 7OG4, 7ODT, 8XT3, 5OOL, 7O9M, 8K2A, 7L20, 6NU2, 7QH7, 3J7Y, 7QI6, 8QU5, 6ZSE, 8QU1, 7OF3, 7OF5, 6ZSC, 6ZSD, 6I9R, 7OF7, 7OF6, 6ZS9, 8K2B, 6ZSB, 6ZM5, 3J9M, 8XT0, 7A5G, 9CN3, 7A5F, 8ANY, 7A5H, 7OID, 7OIB, 7ODS, 7OI6, 7OI9, 7ODR, 8XT1, 7PO4, 6VMI, 5OOM, 7OIE, 7O9K, 7A5K, 6NU3, 8QSJ, 8OIT, 7QH6, 7QI4, 7OF0, 7QI5, 8RRI, 7L08, 7OF4, 7OF2, 8OIR, 6ZSG, 7PD3, 6ZSA, 8PK0

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46199 MTIF2	1	MTIF2 [mitochondrial matrix] (R-HSA-5368271)	0.643	4
UniProt:Q9NSE4 IARS2	1	IARS2 [mitochondrial matrix] (R-HSA-379571)	0.527	2
UniProt:Q8NFP9 NBEA	2	NBEA [cytosol] (R-HSA-9667627) NBEA [nucleoplasm] (R-HSA-9667634)	0.527	3
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [extracellular region] (R-HSA-9017791) YBX1 [nucleoplasm] (R-HSA-72041)	0.527	2
UniProt:Q9BQ52 ELAC2	3	ELAC2 [cytosol] (R-HSA-9708824) ELAC2 [mitochondrial matrix] (R-HSA-6786837) ELAC2 [nucleoplasm] (R-HSA-5696766)	0.527	2
UniProt:Q15031 LARS2	1	LARS2(1-?) [mitochondrial matrix] (R-HSA-379635)	0.527	2
UniProt:P49590 HARS2	1	HARS2 [mitochondrial matrix] (R-HSA-379581)	0.527	3
UniProt:Q5TEU4 NDUFAF5	1	NDUFAF5 [mitochondrial inner membrane] (R-HSA-5689127)	0.527	2
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.527	2

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