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RPP25 [nucleoplasm]
Stable Identifier
R-HSA-5696782
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ribonuclease P protein subunit p25, RPP25_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPP25 [nucleoplasm] (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA processing in the nucleus (Homo sapiens)
RNase P cleaves the 5' end of pre-tRNA (Homo sapiens)
RNase P [nucleoplasm] (Homo sapiens)
RPP25 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BUL9 RPP25
Gene Names
RPP25
Chain
chain:1-199
Reference Genes
BioGPS Gene:54913 RPP25
COSMIC (genes):RPP25 RPP25
CTD Gene:54913 RPP25
dbSNP Gene:54913 RPP25
ENSEMBL:ENSG00000178718.7 RPP25
HGNC:30361 RPP25
KEGG Gene (Homo sapiens):54913 RPP25
Monarch:54913 RPP25
NCBI Gene:54913 RPP25
OMIM:619235 RPP25
UCSC:Q9BUL9 RPP25
Reference Transcript
RefSeq:NM_017793.2 RPP25
Other Identifiers
0006860148
11718300_at
16811745
219143_PM_s_at
219143_s_at
223415_PM_at
223415_at
3633237
3633238
3633239
3633240
3633241
3633242
3633243
54913
55054_at
55083_at
7990442
A_23_P3424
A_33_P3271316
GE55471
GO:0000172
GO:0001682
GO:0003676
GO:0003723
GO:0004526
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005815
GO:0005856
GO:0006364
GO:0006399
GO:0008033
GO:0016787
GO:0030677
GO:0030681
GO:0032991
GO:0033204
GO:0034451
GO:0042254
GO:0043226
GO:0090501
GO:0090502
GO:0140098
HMNXSV003037318
ILMN_1695271
PH_hs_0000908
TC15001653.hg
g8923354_3p_a_at
Participates
as a component of
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RNase P [nucleoplasm] (Homo sapiens)
Inferred To
PSP2 [nucleoplasm]
(Saccharomyces cerevisiae)
RPP25 [nucleoplasm]
(Bos taurus)
RPP25 [nucleoplasm]
(Caenorhabditis elegans)
RPP25 [nucleoplasm]
(Canis familiaris)
RPP25 [nucleoplasm]
(Danio rerio)
RPP25 [nucleoplasm]
(Dictyostelium discoideum)
RPP25 [nucleoplasm]
(Gallus gallus)
RPP25 [nucleoplasm]
(Plasmodium falciparum)
RPP25 [nucleoplasm]
(Sus scrofa)
Ghost homologue of RPP25 [nucleoplasm]
(Schizosaccharomyces pombe)
rpp25 [nucleoplasm]
(Xenopus tropicalis)
Homologues of RPP25 [nucleoplasm]
(Plasmodium falciparum)
Rpp25 [nucleoplasm]
(Drosophila melanogaster)
Rpp25 [nucleoplasm]
(Mus musculus)
Rpp25 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_060263.2
OpenTargets
ENSG00000178718
HPA
ENSG00000178718-RPP25
GeneCards
Q9BUL9
Ensembl
ENST00000322177
,
ENSG00000178718
,
ENSP00000317691
PRO
Q9BUL9
Pharos - Targets
Q9BUL9
PDB
6AHR
,
6LT7
,
6CWX
,
6AHU
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.556
3
UniProt:Q00403 GTF2B
1
GTF2B [nucleoplasm]
(R-HSA-65888)
0.556
3
UniProt:Q96CV9 OPTN
5
OPTN [recycling endosome membrane]
(R-HSA-8854141)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [cytosol]
(R-HSA-9687907)
0.556
3
UniProt:P21673 SAT1
1
SAT1 [cytosol]
(R-HSA-351236)
0.556
8
UniProt:P00441 SOD1
5
SOD1 [extracellular region]
(R-HSA-350705)
2xHC-SOD1 [mitochondrial intermembrane space]
(R-HSA-3777108)
SOD1 [mitochondrial intermembrane space]
(R-HSA-3777082)
SOD1 [cytosol]
(R-HSA-350697)
2xHC-SOD1 [cytosol]
(R-HSA-3299726)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
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