Reactome | RPP25 [nucleoplasm]

RPP25 [nucleoplasm]

Stable Identifier

R-HSA-5696782

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Ribonuclease P protein subunit p25, RPP25_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BUL9 RPP25

Gene Names

RPP25

Chain

chain:1-199

Reference Genes

BioGPS Gene:54913 RPP25

COSMIC (genes):RPP25 RPP25

CTD Gene:54913 RPP25

dbSNP Gene:54913 RPP25

ENSEMBL:ENSG00000178718 RPP25

HGNC:30361 RPP25

Monarch:54913 RPP25

NCBI Gene:54913 RPP25

OMIM:619235 RPP25

UCSC:Q9BUL9 RPP25

Reference Transcript

RefSeq:NM_017793.2 RPP25

Other Identifiers

11718300_at

16811745

219143_PM_s_at

219143_s_at

223415_PM_at

223415_at

3633237

3633238

3633239

3633240

3633241

3633242

3633243

54913

55054_at

55083_at

7990442

A_23_P3424

A_33_P3271316

GE55471

GO:0000172

GO:0001682

GO:0003676

GO:0003723

GO:0003824

GO:0004526

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0006364

GO:0006399

GO:0008033

GO:0016787

GO:0030681

GO:0033204

GO:0034451

GO:0043226

GO:0140098

HMNXSV003037318

ILMN_1695271

PH_hs_0000908

TC15001653.hg

g8923354_3p_a_at

Participates

as a component of

Inferred To

ALBA1 [nucleoplasm] (Plasmodium falciparum)

PSP2 [nucleoplasm] (Saccharomyces cerevisiae)

RPP25 [nucleoplasm] (Bos taurus)

RPP25 [nucleoplasm] (Caenorhabditis elegans)

RPP25 [nucleoplasm] (Canis familiaris)

RPP25 [nucleoplasm] (Gallus gallus)

RPP25 [nucleoplasm] (Sus scrofa)

Ghost homologue of RPP25 [nucleoplasm] (Danio rerio)

Ghost homologue of RPP25 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of RPP25 [nucleoplasm] (Xenopus tropicalis)

ALBA2 [nucleoplasm] (Plasmodium falciparum)

Homologues of RPP25 [nucleoplasm] (Plasmodium falciparum)

Rpp25 [nucleoplasm] (Drosophila melanogaster)

Rpp25 [nucleoplasm] (Mus musculus)

Rpp25 [nucleoplasm] (Rattus norvegicus)

drpp25 [nucleoplasm] (Dictyostelium discoideum)

Cross References

ENSEMBL

ENST00000322177, ENSP00000317691

OpenTargets

ENSG00000178718

HPA

ENSG00000178718-RPP25

PRO

Q9BUL9

Pharos - Targets

Q9BUL9

PDB

6AHR, 6AHU, 6LT7, 6CWX

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00441 SOD1	5	2xHC-SOD1 [cytosol] (R-HSA-3299726) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [extracellular region] (R-HSA-350705)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q00403 GTF2B	1	GTF2B [nucleoplasm] (R-HSA-65888)	0.556	3
UniProt:Q01658 DR1	1	DR1 [nucleoplasm] (R-HSA-3662280)	0.556	3
UniProt:P21673 SAT1	1	SAT1 [cytosol] (R-HSA-351236)	0.556	8
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.556	3
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.556	3
UniProt:P21741 MDK	1	MDK [extracellular region] (R-HSA-2160953)	0.527	2
UniProt:Q92995 USP13	2	USP13 [nucleoplasm] (R-HSA-6781924) USP13 [cytosol] (R-HSA-6781893)	0.527	2

Cite Us!