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K63polyUb-SUDS3 [nucleoplasm]
Stable Identifier
R-HSA-6782790
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SDS3_HUMAN, Sin3 histone deacetylase corepressor complex component, SDS3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP17 deubiquitinates SUDS3 (Homo sapiens)
USP17:K63polyUb-SUDS3 [nucleoplasm] (Homo sapiens)
K63polyUb-SUDS3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H7L9 SUDS3
Gene Names
SUDS3, SAP45, SDS3
Chain
initiator methionine:, chain:2-328
Reference Genes
BioGPS Gene:64426 SUDS3
COSMIC (genes):SUDS3 SUDS3
CTD Gene:64426 SUDS3
dbSNP Gene:64426 SUDS3
ENSEMBL:ENSG00000111707 SUDS3
ENSEMBL_homo_sapiens_GENE:ENSG00000111707.12 SUDS3
HGNC:29545 SUDS3
KEGG Gene (Homo sapiens):64426 SUDS3
Monarch:64426 SUDS3
NCBI Gene:64426 SUDS3
OMIM:608250 SUDS3
UCSC:Q9H7L9 SUDS3
Reference Transcript
RefSeq:NM_022491.2 SUDS3
Other Identifiers
11721516_at
11721517_s_at
11721518_at
16757720
224974_PM_at
224974_at
233841_PM_s_at
233841_s_at
2843472
2843476
2843477
3433844
3433845
3433846
3433848
3433849
3433851
3433855
3433856
3433858
3433860
3433861
3433865
3433866
3433867
3433868
3433869
3433870
3433871
3433875
49355_at
64426
7959080
8110415
83820_at
86160_at
A_23_P334990
GE57012
GO:0000122
GO:0000228
GO:0003824
GO:0004407
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006915
GO:0012501
GO:0016604
GO:0016787
GO:0019899
GO:0021762
GO:0023052
GO:0030336
GO:0030512
GO:0036211
GO:0042826
GO:0043226
GO:0045892
GO:0048856
GO:0048870
GO:0070822
GO:0140096
GO:1902455
GO:1902459
HMNXSV003008364
Hs.20104.0.S1_3p_x_at
Hs.20104.1.S1_3p_a_at
ILMN_1757754
PH_hs_0025055
TC12000928.hg
Participates
as a component of
USP17:K63polyUb-SUDS3 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
SUDS3 [nucleoplasm]
Inferred To
sds3 [nucleoplasm]
(Schizosaccharomyces pombe)
Suds3 [nucleoplasm]
(Mus musculus)
Suds3 [nucleoplasm]
(Rattus norvegicus)
dep1 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of K63polyUb-SUDS3 [nucleoplasm]
(Dictyostelium discoideum)
Homologues of K63polyUb-SUDS3 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of K63polyUb-SUDS3 [nucleoplasm]
(Schizosaccharomyces pombe)
DEP1 [nucleoplasm]
(Saccharomyces cerevisiae)
SDS3 [nucleoplasm]
(Drosophila melanogaster)
SDS3 [nucleoplasm]
(Saccharomyces cerevisiae)
SUDS3 [nucleoplasm]
(Canis familiaris)
SUDS3 [nucleoplasm]
(Sus scrofa)
suds3 [nucleoplasm]
(Danio rerio)
K63polyUb-SUDS3 [nucleoplasm]
(Bos taurus)
K63polyUb-SUDS3 [nucleoplasm]
(Dictyostelium discoideum)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [nucleoplasm]) at unknown position
Modification
K63polyUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_071936.2
OpenTargets
ENSG00000111707
HPA
ENSG00000111707-SUDS3
GeneCards
Q9H7L9
Ensembl
ENSP00000443988
,
ENST00000543473
,
ENSG00000111707
PRO
Q9H7L9
Pharos - Targets
Q9H7L9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13547 HDAC1
2
HDAC1 [nucleoplasm]
(R-HSA-205021)
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(R-HSA-4616030)
0.837
8
UniProt:Q09028 RBBP4
1
RBBP4 [nucleoplasm]
(R-HSA-212223)
0.643
5
UniProt:Q92769 HDAC2
2
monoSUMO1-K462-HDAC2 [nucleoplasm]
(R-HSA-4615958)
HDAC2 [nucleoplasm]
(R-HSA-205135)
0.643
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q16576 RBBP7
1
RBBP7 [nucleoplasm]
(R-HSA-212227)
0.527
4
UniProt:Q9H160 ING2
2
monoSUMO1-K195-ING2 [nucleoplasm]
(R-HSA-4086075)
ING2 [nucleoplasm]
(R-HSA-3215167)
0.527
3
UniProt:Q96ST3 SIN3A
2
SIN3A [nucleoplasm]
(R-HSA-351657)
monoSUMO1-SIN3A [nucleoplasm]
(R-HSA-4086071)
0.527
2
UniProt:P51610 HCFC1
2
HCFC1 [nucleoplasm]
(R-HSA-1592209)
K48polyUb,K63polyUb-HCFC1 [nucleoplasm]
(R-HSA-5690821)
0.499
2
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